G. B. Frost
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View article: Telomerase Reverse Transcriptase Degradation Via a Rationally Designed Covalent Proteolysis Targeting Chimera
Telomerase Reverse Transcriptase Degradation Via a Rationally Designed Covalent Proteolysis Targeting Chimera Open
View article: Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera
Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera Open
Expression of telomerase reverse transcriptase (TERT) is a hallmark of cancer, maintaining telomere length and integrity to enable replicative immortality. However, TERT also serves multiple enzyme-dependent and -independent functions to s…
View article: Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera
Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera Open
Expression of telomerase reverse transcriptase (TERT) is a hallmark of cancer, maintaining telomere length and integrity to enable replicative immortality. However, TERT also serves multiple enzyme-dependent and -independent functions to s…
View article: Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera
Telomerase Reverse Transcriptase Degradation via a Rationally Designed Covalent Proteolysis Targeting Chimera Open
Expression of telomerase reverse transcriptase (TERT) is a hallmark of cancer, maintaining telomere length and integrity to enable replicative immortality. However, TERT also serves multiple enzyme-dependent and -independent functions to s…
View article: Hydrothermal catalysis of waste greases into green gasoline, jet, and diesel biofuels in continuous flow supercritical water
Hydrothermal catalysis of waste greases into green gasoline, jet, and diesel biofuels in continuous flow supercritical water Open
The production of green gasoline, jet, and diesel biofuels from waste greases was achieved using a novel hydrothermal, continuous‐flow catalytic process operating under supercritical water conditions, with recycled water the only added che…
View article: Mechanistic Model for Enantioselective Intramolecular Alkene Cyanoamidation via Palladium-Catalyzed C–CN Bond Activation
Mechanistic Model for Enantioselective Intramolecular Alkene Cyanoamidation via Palladium-Catalyzed C–CN Bond Activation Open
We studied key aspects of the mechanism of Pd-catalyzed C-CN bond activation and intramolecular enantioselective alkene cyanoamidation. An Abboud-Abraham-Kamlet-Taft (AAKT) linear solvation energy relationship (LSER) model for enantioselec…