Abraham Grant Shain
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View article: α Protein Kinase 3 Is Essential for Neonatal and Adult Cardiac Function
α Protein Kinase 3 Is Essential for Neonatal and Adult Cardiac Function Open
Background ALPK3 (α protein kinase 3) is an atypical kinase highly expressed in human and murine hearts. Biallelic loss‐of‐function mutations in ALPK3 lead to pediatric cardiomyopathy. The specific stages at which ALPK3 is essential for ca…
View article: Myocardial Infarction Injury Is Exacerbated by Nicotine in Vape Aerosol Exposure
Myocardial Infarction Injury Is Exacerbated by Nicotine in Vape Aerosol Exposure Open
Background Vaping is touted as a safer alternative to traditional cigarette smoking, but the full spectrum of harm reduction versus comparable risk remains unresolved. Elevated bioavailability of nicotine in vape aerosol together with know…
View article: Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females
Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females Open
Vaping is marketed as a safe alternative to traditional cigarette smoking, but multiple studies demonstrate deleterious cardiopulmonary effects including cardiac function decline and fibrotic remodeling with alveolar size enlargement. Nico…
View article: Myocardial infarction injury is exacerbated by nicotine in vape aerosol exposure
Myocardial infarction injury is exacerbated by nicotine in vape aerosol exposure Open
Rationale Vaping is touted as a safer alternative to traditional cigarette smoking but the full spectrum of harm reduction versus comparable risk remains unresolved. Elevated bioavailability of nicotine in vape aerosol together with known …