J. Gray
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View article: Routine testing for group B streptococcus in pregnancy: protocol for a UK cluster randomised trial (GBS3)
Routine testing for group B streptococcus in pregnancy: protocol for a UK cluster randomised trial (GBS3) Open
Introduction It is unclear whether routine testing of women for group B streptococcus (GBS) colonisation either in late pregnancy or during labour reduces early-onset neonatal sepsis, compared with a risk factor-based strategy. Methods and…
View article: Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT
Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT Open
Background Second trimester miscarriage and preterm birth is a significant global problem. Surgical cervical cerclage is performed to prevent pregnancy loss and preterm birth. It utilises either a monofilament or braided suture. It is hypo…
View article: Should all pregnant women be offered testing for group B streptococcus?
Should all pregnant women be offered testing for group B streptococcus? Open
### What you need to know
Introducing routine testing for group B streptococcus (GBS) for all women in late pregnancy would likely reduce cases of early onset infection in their newborns, but might also increase the number of women given …
View article: Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT
Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT Open
Background Clinical trials show that antimicrobial-impregnated central venous catheters reduce catheter-related bloodstream infection in adults and children receiving intensive care, but there is insufficient evidence for use in newborn ba…
View article: Best Practice Statement: Antimicrobial stewardship strategies for wound management
Best Practice Statement: Antimicrobial stewardship strategies for wound management Open
The aim of this document is to:* Raise awareness of antimicrobial stewardship (AMS) within wound care in the UK* Establish the role of wound care in the wider landscape of AMS* Promote achievable AMS practices for all involved in the care …
View article: P65 Advanced neonatal nurse practitioner (ANNP) review of neonatal antibiotics in 36hours to improve antibiotics stewardship
P65 Advanced neonatal nurse practitioner (ANNP) review of neonatal antibiotics in 36hours to improve antibiotics stewardship Open
Aim To ensure neonates in transitional care and postnatal wards are receiving antibiotics appropriately. NICE CG149 1 advises to consider stopping antibiotics at 36 hours in babies given antibiotics because of risk factors for infection or…
View article: Linking surveillance and clinical data for evaluating trends in bloodstream infection rates in neonatal units in England
Linking surveillance and clinical data for evaluating trends in bloodstream infection rates in neonatal units in England Open
Linkage that combines BSI records from national laboratory surveillance and clinical NNU data sources, and use of probabilistic methods, substantially improved ascertainment of BSI and estimates of BSI trends over time, compared with singl…
View article: Intravenous co-amoxiclav to prevent infection after operative vaginal delivery: the ANODE RCT
Intravenous co-amoxiclav to prevent infection after operative vaginal delivery: the ANODE RCT Open
Background Sepsis is a leading cause of direct and indirect maternal death in both the UK and globally. All forms of operative delivery are associated with an increased risk of sepsis, and the National Institute for Health and Care Excelle…
View article: A Pragmatic Study to Evaluate the Use of a Rapid Diagnostic Test to Detect Group A Streptococcal Pharyngitis in Children With the Aim of Reducing Antibiotic Use in a UK Emergency Department
A Pragmatic Study to Evaluate the Use of a Rapid Diagnostic Test to Detect Group A Streptococcal Pharyngitis in Children With the Aim of Reducing Antibiotic Use in a UK Emergency Department Open
Objective Sore throat is a common presentation to the children's emergency department (ED), and many patients are likely prescribed antibiotics unnecessarily. We aimed to reduce antibiotic prescribing for sore throat in our UK ED through u…