Greg D. Learn
YOU?
Author Swipe
View article: Corrigendum to “A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders”
Corrigendum to “A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders” Open
The authors note that text was omitted from the conclusions section of the published abstract. The full, corrected abstract is provided below: Abstract Introduction: Powder hemostats are valuable adjuncts to minimize intra-operative and po…
View article: Mesenchymal Stem Cell Delivery via Topographically Tenoinductive Collagen Biotextile Enhances Regeneration of Segmental Tendon Defects
Mesenchymal Stem Cell Delivery via Topographically Tenoinductive Collagen Biotextile Enhances Regeneration of Segmental Tendon Defects Open
Background: Successful management of massive rotator cuff (RC) tendon tears represents a treatment challenge because of the limited intrinsic healing capacity of native tendons and the risk of repair failure. Biologic augmentation of massi…
View article: Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections <i>In Vivo</i>
Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections <i>In Vivo</i> Open
While orthopedic implant-associated infections are rare, revision surgeries resulting from infections incur considerable healthcare costs and represent a substantial research area clinically, in academia, and in industry. In recent years, …
View article: A PMMA bone cement composite that functions as a drug-refillable depot for localized, multi-window chemotherapeutic treatment of bone cancer
A PMMA bone cement composite that functions as a drug-refillable depot for localized, multi-window chemotherapeutic treatment of bone cancer Open
Standard chemotherapy for primary and secondary bone tumors typically involves systemic administration of chemotherapeutic drugs, such as doxorubicin (DOX). However, non-targeted delivery increases dose requirements, and results in off-tar…
View article: Poly(methyl methacrylate) Bone Cement Composite Can Be Refilled with Antibiotics after Implantation in Femur or Soft Tissue
Poly(methyl methacrylate) Bone Cement Composite Can Be Refilled with Antibiotics after Implantation in Femur or Soft Tissue Open
While periprosthetic joint infections (PJIs) result in a small percentage of patients following arthroplasties, they are challenging to treat if they spread into bone and soft tissue. Treatment involves delivering antibiotics using poly(me…
View article: Nonthermal Plasma Treatment Improves Uniformity and Adherence of Cyclodextrin-Based Coatings on Hydrophobic Polymer Substrates
Nonthermal Plasma Treatment Improves Uniformity and Adherence of Cyclodextrin-Based Coatings on Hydrophobic Polymer Substrates Open
Low surface energy substrates, which include many plastics and polymers, present challenges toward achieving uniform, adherent coatings, thus limiting intended coating function. These inert materials are common in various applications due …
View article: Cyclodextrin polymer coatings resist protein fouling, mammalian cell adhesion, and bacterial attachment
Cyclodextrin polymer coatings resist protein fouling, mammalian cell adhesion, and bacterial attachment Open
Undesired attachment of proteins, cells/bacteria, and organisms on material surfaces is problematic in industrial and health care settings. In this study, polymer coatings are synthesized from subunits of cyclodextrin, an additive/excipien…
View article: Using nonthermal plasma treatment to improve quality and durability of hydrophilic coatings on hydrophobic polymer surfaces
Using nonthermal plasma treatment to improve quality and durability of hydrophilic coatings on hydrophobic polymer surfaces Open
Low surface energy substrates, which include many polymers in medicine/industry, present challenges toward achieving uniform, adherent, durable coatings, thus limiting intended coating function. Examples include hydrophobic polymers such a…
View article: Nonthermal plasma treatment of polymers modulates biological fouling but can cause material embrittlement
Nonthermal plasma treatment of polymers modulates biological fouling but can cause material embrittlement Open
Plasma-based treatment is a prevalent strategy to alter biological response and enhance biomaterial coating quality at the surfaces of biomedical devices and implants, especially polymeric materials. Plasma, an ionized gas, is often though…
View article: Use of affinity allows anti‐inflammatory and anti‐microbial dual release that matches suture wound resolution
Use of affinity allows anti‐inflammatory and anti‐microbial dual release that matches suture wound resolution Open
Surgical sutures are vulnerable to bacterial infections and biofilm formation. At the suture site, pain and undesirable, excess inflammation are additionally detrimental to wound healing. The development of a polymerized cyclodextrin (pCD)…
View article: Woven collagen biotextiles enable mechanically functional rotator cuff tendon regeneration during repair of segmental tendon defects <i>in vivo</i>
Woven collagen biotextiles enable mechanically functional rotator cuff tendon regeneration during repair of segmental tendon defects <i>in vivo</i> Open
Despite advancements in surgical techniques and materials for rotator cuff repair procedures, primary repair failures remain common. This study examines the use of electrochemically aligned collagen (ELAC) threads woven into biotextile sca…
View article: Bone Cements: An Additive to PMMA Bone Cement Enables Postimplantation Drug Refilling, Broadens Range of Compatible Antibiotics, and Prolongs Antimicrobial Therapy (Adv. Healthcare Mater. 21/2018)
Bone Cements: An Additive to PMMA Bone Cement Enables Postimplantation Drug Refilling, Broadens Range of Compatible Antibiotics, and Prolongs Antimicrobial Therapy (Adv. Healthcare Mater. 21/2018) Open
Insoluble polymerized cyclodextrin microparticles entrap antibiotics in bone cement. The cement is then implanted into total joint replacements and is used to treat prolonged infections. In article 1800812, Horst A. von Recum and co-worker…