Gregg E. Dinse
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View article: Decreased cigarette smoking may partially explain the increased prevalence of antinuclear antibodies in the United States
Decreased cigarette smoking may partially explain the increased prevalence of antinuclear antibodies in the United States Open
Introduction Despite well-known harmful health effects of smoking, research supports an inverse association with some autoimmune diseases. High-titer antinuclear antibodies (ANA) are associated with autoimmune diseases, and ANA prevalence …
View article: Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system
Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system Open
In this article, we provide a proof of concept evaluating the utility of the U.S. Tox21 high-throughput screening approach to assess the hazard of chemical mixtures using 2 estrogen receptor (ER) assays. A subset of chemicals identified in…
View article: Anti-dense fine speckled 70 (DFS70) autoantibodies: correlates and increasing prevalence in the United States
Anti-dense fine speckled 70 (DFS70) autoantibodies: correlates and increasing prevalence in the United States Open
Objective Recent studies report high-titer anti-dense fine speckled 70 (DFS70) autoantibodies in persons with inflammatory conditions, but the clinical significance remains unclear. Our goals were to estimate anti-DFS70 autoantibody preval…
View article: Hygiene Hypothesis Indicators and Prevalence of Antinuclear Antibodies in US Adolescents
Hygiene Hypothesis Indicators and Prevalence of Antinuclear Antibodies in US Adolescents Open
Autoimmunity prevalence, as measured by antinuclear antibodies (ANA), is increasing in U.S. adolescents. Improved hygiene and cleaner environments in childhood may reduce exposure to infections and other immune challenges, resulting in imp…
View article: Early-life Farm Exposure and Ovarian Reserve in a US Cohort of Women
Early-life Farm Exposure and Ovarian Reserve in a US Cohort of Women Open
Background: In a previous exploratory study, we reported lower concentrations of the ovarian reserve biomarker anti-Müllerian hormone (AMH) in adulthood with prenatal farm exposure. We now examine this association as well as childhood farm…
View article: Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999–2004
Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999–2004 Open
Dinse GE, Jusko TA, Whitt IZ, Co CA, Parks CG, Satoh M, Chan EKL, Rose KM, Walker NJ, Birnbaum LS, Zeldin DC, Weinberg CR, Miller FW. 2016. Associations between selected xenobiotics and antinuclear antibodies in the National Health and Nut…