Gregory Carter
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View article: The Bayesian Global Sky Model (B-GSM): validation of a data-driven Bayesian simultaneous component separation and calibration algorithm for EoR foreground modelling
The Bayesian Global Sky Model (B-GSM): validation of a data-driven Bayesian simultaneous component separation and calibration algorithm for EoR foreground modelling Open
We introduce the Bayesian Global Sky Model (B-GSM), a novel data-driven Bayesian approach to modelling radio foregrounds at frequencies <400 MHz. B-GSM aims to address the limitations of previous models by incorporating robust error qua…
View article: Machine learning algorithms and their predictive accuracy for suicide and self-harm: Systematic review and meta-analysis
Machine learning algorithms and their predictive accuracy for suicide and self-harm: Systematic review and meta-analysis Open
Background There has been rapid expansion in the development of machine learning algorithms to predict suicidal behaviours. To test the accuracy of these algorithms for predicting suicide and hospital-treated self-harm, we undertook a syst…
View article: Simulation of a ‘suicidal mind’: Using the Integrated Motivational Volitional model of suicide to demonstrate dynamic suicidal states
Simulation of a ‘suicidal mind’: Using the Integrated Motivational Volitional model of suicide to demonstrate dynamic suicidal states Open
Suicidal behaviors are characterised by complex, multi-factorial aetiology. Dynamic simulation models (DSMs) are computational approaches that can explicitly capture salient dimensions of complex suicidal thinking and behavior. This study …
View article: Corrigendum: People who die by suicide without receiving mental health services: a systematic review
Corrigendum: People who die by suicide without receiving mental health services: a systematic review Open
[This corrects the article DOI: 10.3389/fpubh.2021.736948.].
View article: DNA methylation changes in a pharmaco-epigenomic EWAS in depression: comparing fixed and response-guided dosing paradigms for ketamine in the KADS trial
DNA methylation changes in a pharmaco-epigenomic EWAS in depression: comparing fixed and response-guided dosing paradigms for ketamine in the KADS trial Open
DNA methylation is a dynamic biomarker suited to investigate processes, e.g., treatment response. We investigate DNA methylation changes in different dosing paradigms for ketamine (s.c.) vs. midazolam (s.c.) in treatment resistant depresse…
View article: The Bayesian Global Sky Model (B-GSM): A Calibrated Low Frequency Sky Model for EoR Applications
The Bayesian Global Sky Model (B-GSM): A Calibrated Low Frequency Sky Model for EoR Applications Open
We present the Bayesian Global Sky Model (B-GSM), a new absolutely calibrated model of the diffuse Galactic foreground at frequencies below 408 MHz. We assemble a dataset of publicly available diffuse emission maps at frequencies between 4…
View article: Systematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment, and Participant Moderators
Systematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment, and Participant Moderators Open
STUDY PREREGISTRATION INFORMATION: Reducing Self-harm in Adolescents: An Individual Participant Data Meta-analysis; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=152119.
View article: Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study
Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study Open
Background Anxiety disorders and treatment-resistant major depressive disorder (TRD) are often comorbid. Studies suggest ketamine has anxiolytic and antidepressant properties. Aims To investigate if subcutaneous racemic ketamine, delivered…
View article: The Bayesian Global Sky Model (B-GSM): Validation of a Data Driven Bayesian Simultaneous Component Separation and Calibration Algorithm for EoR Foreground Modelling
The Bayesian Global Sky Model (B-GSM): Validation of a Data Driven Bayesian Simultaneous Component Separation and Calibration Algorithm for EoR Foreground Modelling Open
We introduce the Bayesian Global Sky Model (B-GSM), a novel data-driven Bayesian approach to modelling radio foregrounds at frequencies <400~MHz. B-GSM aims to address the limitations of previous models by incorporating robust error quanti…
View article: Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool
Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool Open
Importance: Test accuracy studies often use small datasets to simultaneously select an optimal cutoff score that maximizes test accuracy and generate accuracy estimates. Objective: To evaluate the degree to which using data-driven methods …
View article: Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool
Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool Open
Importance Test accuracy studies often use small datasets to simultaneously select an optimal cutoff score that maximizes test accuracy and generate accuracy estimates. Objective To evaluate the degree to which using data-driven methods to…
View article: Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial – CORRIGENDUM
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial – CORRIGENDUM Open
View article: Correction to: A double-blind, placebo-controlled, randomized trial of PXT3003 for the treatment of Charcot–Marie–Tooth type 1A
Correction to: A double-blind, placebo-controlled, randomized trial of PXT3003 for the treatment of Charcot–Marie–Tooth type 1A Open
View article: Shortening self-report mental health symptom measures through optimal test assembly methods: Development and validation of the Patient Health Questionnaire-Depression-4
Shortening self-report mental health symptom measures through optimal test assembly methods: Development and validation of the Patient Health Questionnaire-Depression-4 Open
Background: The objective of this study was to develop and validate a short form of the Patient Health Questionnaire-9 (PHQ-9), a self-report questionnaire for assessing depressive symptomatology, using objective criteria. Methods: Respons…
View article: Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: A systematic review and individual participant data meta-analysis
Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: A systematic review and individual participant data meta-analysis Open
Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The…
View article: The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis
The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis Open
Background: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9) can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies publish results for only one approach, and previous meta-analyses…
View article: Cognitive outcomes from the randomised, active-controlled Ketamine for Adult Depression Study (KADS)
Cognitive outcomes from the randomised, active-controlled Ketamine for Adult Depression Study (KADS) Open
The findings support the cognitive safety of repeated fixed and escalating doses at least in the short-term in people with treatment resistant MDD.
View article: Expecting the unexpected: DNA methylation changes after a single dose of ketamine?
Expecting the unexpected: DNA methylation changes after a single dose of ketamine? Open
View article: Global prevalence of psychosocial assessment following hospital-treated self-harm: systematic review and meta-analysis
Global prevalence of psychosocial assessment following hospital-treated self-harm: systematic review and meta-analysis Open
Background Hospital-treated self-harm is common, costly and associated with repeated self-harm and suicide. Providing a comprehensive psychosocial assessment following self-harm is recommended by professional bodies and may improve outcome…
View article: Association of blood-based inflammatory proteins with MADRS change after repeated subcutaneous ketamine injections in treatment-resistant depressive patients
Association of blood-based inflammatory proteins with MADRS change after repeated subcutaneous ketamine injections in treatment-resistant depressive patients Open
View article: Pharmacogenomic interactions of ketamine and BDNF genetic variants in patients with treatment-resistant depression
Pharmacogenomic interactions of ketamine and BDNF genetic variants in patients with treatment-resistant depression Open
View article: Longitudinal analysis of differentially expressed genes in pharmacologically treated patients with treatment-resistant depression
Longitudinal analysis of differentially expressed genes in pharmacologically treated patients with treatment-resistant depression Open
View article: Somatic symptom severity, depression and anxiety associations with pancreatitis and undifferentiated abdominal pain in surgical inpatients
Somatic symptom severity, depression and anxiety associations with pancreatitis and undifferentiated abdominal pain in surgical inpatients Open
Background Somatic Symptom Disorder is a psychiatric diagnosis that describes the experience of physical symptoms and associated distress, that is disproportionate to recognized organic pathology. Somatic symptom severity (SSS) may be asso…
View article: Efficacy of a short message service brief contact intervention (SMS-SOS) in reducing repetition of hospital-treated self-harm: randomised controlled trial
Efficacy of a short message service brief contact intervention (SMS-SOS) in reducing repetition of hospital-treated self-harm: randomised controlled trial Open
Background Hospital-treated self-harm is common and costly, and is associated with repeated self-harm and suicide. Aims To investigate the effectiveness of a brief contact intervention delivered via short message service (SMS) text message…
View article: Global prevalence of psychiatric in- and out-patient treatment following hospital-presenting self-harm: a systematic review and meta-analysis
Global prevalence of psychiatric in- and out-patient treatment following hospital-presenting self-harm: a systematic review and meta-analysis Open
There was no specific funding for this review.
View article: Situational anxiety in head and neck cancer: Rates, patterns and clinical management interventions in a regional cancer setting
Situational anxiety in head and neck cancer: Rates, patterns and clinical management interventions in a regional cancer setting Open
Introduction Research indicates that the immobilisation mask required for radiation therapy (RT) for head and neck cancers can provoke intense anxiety. However, little is known about the rates of this anxiety, whether it changes over a cou…
View article: The many faces of obstructive sleep apnea
The many faces of obstructive sleep apnea Open
Obstructive sleep apnea is a common disorder with many different comorbidities. Patients can present with these comorbidities even when sleep apnea has not been diagnosed due to the low diagnostic rates for obstructive sleep apnea worldwid…
View article: Five healthcare trajectories in the year before suicide and what they tell us about opportunities for prevention: a population-level case series study
Five healthcare trajectories in the year before suicide and what they tell us about opportunities for prevention: a population-level case series study Open
View article: Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm
Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm Open
Background Prior self-harm represents the most significant risk factor for future self-harm or suicide. Aim To evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordinat…
View article: ALSUntangled #71: Nuedexta
ALSUntangled #71: Nuedexta Open
Nuedexta is a combination of dextromethorphan hydrobromide and quinidine sulfate and was approved by the Food and Drug Administration (FDA) in 2010 to treat pseudobulbar affect (PBA). There have since been anecdotal case reports of bulbar …