Gregory H. Borschel
YOU?
Author Swipe
View article: Journal of Brachial Plexus and Peripheral Nerve Injury
Journal of Brachial Plexus and Peripheral Nerve Injury Open
► nerve transfer ► peripheral nerve surgery ► ulnar nerve ► median nerve ► plastic surgery ► ulnar nerve trauma ► anterior interosseous nerve ► deep motor branch ulnar nerve
View article: Parent-Reported Outcomes Following Type B Ulnar Polydactyly Excision in the Clinic Versus the Operating Room
Parent-Reported Outcomes Following Type B Ulnar Polydactyly Excision in the Clinic Versus the Operating Room Open
Background: Ulnar polydactyly is the presence of an extra finger on the post-axial aspect of the hand. It is one of the most common congenital abnormalities and causes aesthetic and functional impairments that can be treated with surgical …
View article: SO9. New Hope For Patients With Neurotrophic Keratopathy: Molecular Interactions Governing Nerve-mediated Control Of Corneal Epithelial Renewal And Wound Healing
SO9. New Hope For Patients With Neurotrophic Keratopathy: Molecular Interactions Governing Nerve-mediated Control Of Corneal Epithelial Renewal And Wound Healing Open
PURPOSE: Corneal clarity, essential for vision, is maintained by limbal stem cells (LSCs), which generate transparent limbal epithelial cells. Corneal sensory nerves, beyond their protective role, are believed to stimulate LSCs via unknown…
View article: 153. Exploring NGF Mechanisms in Innervation-dependent Corneal Healing: Novel Therapies for Neurotrophic Keratopathy
153. Exploring NGF Mechanisms in Innervation-dependent Corneal Healing: Novel Therapies for Neurotrophic Keratopathy Open
View article: 27. A Novel Rodent Model for Neurotrophic Keratopathy: Retro-orbital Nasociliary Neurotomy
27. A Novel Rodent Model for Neurotrophic Keratopathy: Retro-orbital Nasociliary Neurotomy Open
View article: Biohacking Nerve Repair: Novel Biomaterials, Local Drug Delivery, Electrical Stimulation, and Allografts to Aid Surgical Repair
Biohacking Nerve Repair: Novel Biomaterials, Local Drug Delivery, Electrical Stimulation, and Allografts to Aid Surgical Repair Open
The regenerative capacity of the peripheral nervous system is limited, and peripheral nerve injuries often result in incomplete healing and poor outcomes even after repair. Transection injuries that induce a nerve gap necessitate microsurg…
View article: Corneal Nerve Assessment by Aesthesiometry: History, Advancements, and Future Directions
Corneal Nerve Assessment by Aesthesiometry: History, Advancements, and Future Directions Open
The measurement of corneal sensation allows clinicians to assess the status of corneal innervation and serves as a crucial indicator of corneal disease and eye health. Many devices are available to assess corneal sensation, including the C…
View article: 07. The Mechanism of NGF Signaling In Innervation-dependent Corneal Epithelial Renewal: New Topical Treatment For Neurotrophic Keratopathy
07. The Mechanism of NGF Signaling In Innervation-dependent Corneal Epithelial Renewal: New Topical Treatment For Neurotrophic Keratopathy Open
Background: Corneal clarity is essential for vision. Limbal stem cells (LSCs), the source of transparent corneal epithelial cells, are located in the basal epithelium of the limbus at the corneal-conjunctival interface, where they interact…
View article: 46. The Role Of Early Latissimus Dorsi Tendon Transfers For Shoulder Movement And Stability In Neonatal Brachial Plexus Injury
46. The Role Of Early Latissimus Dorsi Tendon Transfers For Shoulder Movement And Stability In Neonatal Brachial Plexus Injury Open
Purpose: Neonatal brachial plexus injury (BPI) is a rare but devastating complication of birth. An upper trunk BPI can result in the loss of shoulder external rotation and abduction and often leads to glenohumeral joint dysplasia (GJD). Th…
View article: A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair
A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair Open
JOURNAL/nrgr/04.03/01300535-202501000-00036/figure1/v/2025-06-04T152002Z/r/image-tiff Axonal regeneration following surgical nerve repair is slow and often incomplete, resulting in poor functional recovery which sometimes contributes to li…
View article: Corneal Neurotization: Preoperative Patient Workup and Surgical Decision-making
Corneal Neurotization: Preoperative Patient Workup and Surgical Decision-making Open
Background: The use of sensory nerve transfers to the anesthetic cornea has transformed the treatment of neurotrophic keratopathy by restoring ocular surface sensation and activating dysfunctional epithelial repair mechanisms. However, des…
View article: The Role of Early Latissimus Dorsi Tendon Transfers for Shoulder Movement and Stability in Neonatal Brachial Plexus Injury
The Role of Early Latissimus Dorsi Tendon Transfers for Shoulder Movement and Stability in Neonatal Brachial Plexus Injury Open
INTRODUCTION: Neonatal brachial plexus injury (BPI) is a rare but devastating complication of birth. An upper trunk BPI can result in the loss of shoulder external rotation and abduction and often leads to glenohumeral joint dysplasia (GJD…
View article: Surgical Management of Sirenomelia: A Case Study
Surgical Management of Sirenomelia: A Case Study Open
Background: Sirenomelia is a rare congenital condition characterized by fusion of the lower limbs. Patients with sirenomelia generally do not survive long after birth because the condition is associated with multisystem organ dysfunction d…
View article: The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal
The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal Open
The cornea is the window through which we see the world. Corneal clarity is required for vision, and blindness occurs when the cornea becomes opaque. The cornea is covered by unique transparent epithelial cells that serve as an outermost c…
View article: 56. Foretinib Enhances Myelination of Neurons in Vitro
56. Foretinib Enhances Myelination of Neurons in Vitro Open
BACKGROUND: Nerve injuries cause significant functional impairment. Despite advanced diagnostic methods and microsurgical procedures, recovery after peripheral nerve repair is often disappointing. Therefore, new therapeutics are needed to …
View article: Schwann Cells Are Key Regulators of Corneal Epithelial Renewal
Schwann Cells Are Key Regulators of Corneal Epithelial Renewal Open
Limbal SCs are required for innervation-dependent corneal epithelial renewal.
View article: Peripheral Nerve Matrix Hydrogel Promotes Recovery after Nerve Transection and Repair
Peripheral Nerve Matrix Hydrogel Promotes Recovery after Nerve Transection and Repair Open
Background: Nerve transection is the most common form of peripheral nerve injury. Treatment of peripheral nerve injury has primarily focused on stabilization and mechanical cues to guide extension of the regenerating growth cone across the…
View article: Delay modulates the immune response to nerve repair
Delay modulates the immune response to nerve repair Open
View article: Evaluation of Cost and Parental Satisfaction in Type B Polydactyly Excision Completed in Office Vs. Operating Room
Evaluation of Cost and Parental Satisfaction in Type B Polydactyly Excision Completed in Office Vs. Operating Room Open
Background/Objective:One in 500 children in the US are born with polydactyly, extra digits on hands or feet. Out of those children, 95% of cases comprise of type B polydactyly, in which the extra digit is attached by neurovascular bundle w…
View article: Outcomes after Anterior Interosseous Nerve to Ulnar Motor Nerve Transfer
Outcomes after Anterior Interosseous Nerve to Ulnar Motor Nerve Transfer Open
Background Ulnar nerve lesions proximal to the elbow can result in loss of intrinsic muscle function of the hand. The anterior interosseous nerve (AIN) to deep motor branch of the ulnar nerve (DBUN) transfer has been demonstrated to provid…
View article: Supraclavicular Approach to the Brachial Plexus.
Supraclavicular Approach to the Brachial Plexus. Open
The supraclavicular dissection of the brachial plexus is reliable with consistent landmarks and can be carried out in a stepwise fashion.
View article: Sustained Release of Tacrolimus From a Topical Drug Delivery System Promotes Corneal Reinnervation
Sustained Release of Tacrolimus From a Topical Drug Delivery System Promotes Corneal Reinnervation Open
Topically applied tacrolimus may provide a readily translatable approach to promote corneal reinnervation.
View article: 72. The Role of TrkA And P75NTR NGF Receptors in Corneal Wound Healing
72. The Role of TrkA And P75NTR NGF Receptors in Corneal Wound Healing Open
Purpose: The cornea is the window through which we see the world and is one of the most densely innervated structures in the body. Besides providing protective sensory input, corneal nerves may also stimulate limbal stem cells (LSCs), gove…
View article: 105. Long Term Surgical and Patient Reported Outcomes After Cross Face Nerve Graft Reconstruction in Pediatric Facial Paralysis
105. Long Term Surgical and Patient Reported Outcomes After Cross Face Nerve Graft Reconstruction in Pediatric Facial Paralysis Open
Purpose: Free functioning muscle transfer is the gold standard for pediatric facial paralysis reconstruction and using the contralateral facial nerve for neurotization via a cross face nerve graft enables spontaneous smile restoration. Out…
View article: VP1: Combined Local Delivery of Tacrolimus and Stem Cells in Fibrin Gel is a Viable Potential Treatment for Enhancing Peripheral Nerve Regeneration
VP1: Combined Local Delivery of Tacrolimus and Stem Cells in Fibrin Gel is a Viable Potential Treatment for Enhancing Peripheral Nerve Regeneration Open
INTRODUCTION: The immunosuppressive and neuroregenerative potential of tacrolimus (FK506) may overcome the rejection of stem cells to enhance nerve regeneration. The aim of this study was to determine the feasibility and effectiveness of c…
View article: VP6: Sustained Topical Release of Tacrolimus Promotes Corneal Reinnervation in Rats
VP6: Sustained Topical Release of Tacrolimus Promotes Corneal Reinnervation in Rats Open
INTRODUCTION: Corneal nerve fibers provide sensibility and maintain ocular surface health. Impaired corneal innervation results in progressive corneal breakdown and vision loss termed neurotrophic keratopathy. Non-surgical therapies that p…
View article: VP2: Mesenchymal Stem Cells and Local Tacrolimus Delivery Synergistically Enhance Neurite Extension
VP2: Mesenchymal Stem Cells and Local Tacrolimus Delivery Synergistically Enhance Neurite Extension Open
INTRODUCTION: Application of mesenchymal stem cells (MSCs) or tacrolimus (FK506), an FDA approved immunosuppressant, to nerve grafts has been a topic of interest to enhance peripheral nerve regeneration. The aim of this study was to invest…
View article: A Biodegradable, Tacrolimus-releasing Nerve Wrap Promotes Peripheral Nerve Regeneration
A Biodegradable, Tacrolimus-releasing Nerve Wrap Promotes Peripheral Nerve Regeneration Open
Axonal regeneration following nerve repair is slow and often incomplete, resulting in poor functional recovery and sometimes lifelong disability. Yet, there are no FDA-approved therapies available to promote nerve regeneration. Tacrolimus …
View article: Schwann Cells Are Required for Efficient Corneal Wound Healing
Schwann Cells Are Required for Efficient Corneal Wound Healing Open
BACKGROUND: Corneal nerves play a crucial role in maintaining corneal health, which includes regulation of activity of limbal stem cell (LSC). Their loss leads to neurotrophic keratopathy (NK), with corneal ulceration, scarring, and ultima…