Grigori Joffe
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View article: Changes in depression medication following the initial assessment by specialised psychiatry services in the Helsinki-Uusimaa Region
Changes in depression medication following the initial assessment by specialised psychiatry services in the Helsinki-Uusimaa Region Open
Introduction Depressive disorders often require specialised psychiatric services. Timely, appropriate medication initiation and/or change plays a crucial role in improving patient (pt) outcomes (Kraus et al. Transl Psychiatry 2019;9 127). …
View article: Machine learned text topics improve drop-out risk prediction but not symptom prediction in online psychotherapies for depression and anxiety
Machine learned text topics improve drop-out risk prediction but not symptom prediction in online psychotherapies for depression and anxiety Open
Objective: Internet-delivered cognitive behavior therapies (iCBT) are effective and scalable treatments for depression and anxiety. However, treatment adherence remains a major limitation that could be further understood by applying…
View article: The Overall Anxiety Severity and Impairment Scale as an Outcome Measure in Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders: Observational Study
The Overall Anxiety Severity and Impairment Scale as an Outcome Measure in Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders: Observational Study Open
Background Internet-delivered cognitive behavioral therapy (iCBT) is effective in the treatment of anxiety disorders. iCBT clinical trials use relatively long and time-consuming disorder-specific rather than transdiagnostic anxiety measure…
View article: The Overall Anxiety Severity and Impairment Scale as an Outcome Measure in Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders: Observational Study (Preprint)
The Overall Anxiety Severity and Impairment Scale as an Outcome Measure in Internet-Delivered Cognitive Behavioral Therapy for Anxiety Disorders: Observational Study (Preprint) Open
BACKGROUND Internet-delivered cognitive behavioral therapy (iCBT) is effective in the treatment of anxiety disorders. iCBT clinical trials use relatively long and time-consuming disorder-specific rather than transdiagnostic anxiety measur…
View article: Text Topics and Treatment Response in Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder: Text Mining Study
Text Topics and Treatment Response in Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder: Text Mining Study Open
Background Text mining methods such as topic modeling can offer valuable information on how and to whom internet-delivered cognitive behavioral therapies (iCBT) work. Although iCBT treatments provide convenient data for topic modeling, it …
View article: Effectiveness of mobile-delivered, therapist-assisted cognitive behavioral therapy for insomnia in nationwide routine clinical care in Finland
Effectiveness of mobile-delivered, therapist-assisted cognitive behavioral therapy for insomnia in nationwide routine clinical care in Finland Open
View article: Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study
Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study Open
Background Therapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficacious for generalized anxiety disorder (GAD), but few studies are yet to report its effectiveness in routine care. Objective In this study, we …
View article: Measurement Invariant but Non-Normal Treatment Responses in Guided Internet Psychotherapies for Depressive and Generalized Anxiety Disorders
Measurement Invariant but Non-Normal Treatment Responses in Guided Internet Psychotherapies for Depressive and Generalized Anxiety Disorders Open
Assessment of treatment response in psychotherapies can be undermined by lack of longitudinal measurement invariance (LMI) in symptom self-report inventories, by measurement error, and/or by wrong model assumptions. To understand and compa…
View article: Internet-delivered Cognitive-Behavioral Therapy for Generalized Anxiety Disorder: Its Effectiveness in Nationwide Routine Care (Preprint)
Internet-delivered Cognitive-Behavioral Therapy for Generalized Anxiety Disorder: Its Effectiveness in Nationwide Routine Care (Preprint) Open
BACKGROUND Internet-delivered, therapist-supported Cognitive Behavioral Therapy (iCBT) is efficacious for Generalized Anxiety Disorder (GAD), but few studies have as yet reported its effectiveness in routine care. OBJECTIVE To examine w…
View article: eConsultation between health care professionals in primary health care and specialized medical care
eConsultation between health care professionals in primary health care and specialized medical care Open
The synchronous eConsultation is provided by a specialist in a hospital to a GP appointment either by pre-set request or without scheduling. The patient participates in the session. The eConsultation employs video or chat and the program i…
View article: Scheduled Telephone Support for Internet Cognitive Behavioral Therapy for Depression in Patients at Risk for Dropout: Pragmatic Randomized Controlled Trial
Scheduled Telephone Support for Internet Cognitive Behavioral Therapy for Depression in Patients at Risk for Dropout: Pragmatic Randomized Controlled Trial Open
Background Therapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficient in the treatment of depression. However, the optimal mode and intensity of therapist support remain to be identified. Scheduled telephone s…
View article: Scheduled Telephone Support for Internet Cognitive Behavioral Therapy for Depression in Patients at Risk for Dropout: Pragmatic Randomized Controlled Trial (Preprint)
Scheduled Telephone Support for Internet Cognitive Behavioral Therapy for Depression in Patients at Risk for Dropout: Pragmatic Randomized Controlled Trial (Preprint) Open
BACKGROUND Therapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficient in the treatment of depression. However, the optimal mode and intensity of therapist support remain to be identified. Scheduled telephone …
View article: Reducing health inequalities trough digital options in mental health: A physician’s perspective
Reducing health inequalities trough digital options in mental health: A physician’s perspective Open
This article explores the physicians' perspective regarding the potential of computerized cognitive behavioral therapies (cCBTs) to overcome inequalities in the context of mental health care provision. The main benefits were related to the…
View article: Lääkärien suhtautuminen nettiterapiaan positiivista mutta varovaista
Lääkärien suhtautuminen nettiterapiaan positiivista mutta varovaista Open
Nettiterapiat tarjoavat lääkärien näkökulmasta hyväksytyn tavan tarjota hoitoa. Kyselytutkimuksessa lääkärit katsoivat ne kuitenkin alkuvaiheen hoitoa täydentäväksi lisäksi eikä ainoaksi hoitovaihtoehdoksi. Nettiterapiaei saisi jäädä irral…
View article: Standard comparison of local mental health care systems in eight European countries
Standard comparison of local mental health care systems in eight European countries Open
Aims. There is a need of more quantitative standardised data to compare local Mental Health Systems (MHSs) across international jurisdictions. Problems related to terminological variability and commensurability in the evaluation of service…
View article: Identifying Local and Centralized Mental Health Services—The Development of a New Categorizing Variable
Identifying Local and Centralized Mental Health Services—The Development of a New Categorizing Variable Open
The challenges of mental health and substance abuse services (MHS) require shifting of the balance of resources from institutional care to community care. In order to track progress, an instrument that can describe these attributes of MHS …
View article: A Comparison of Mental Health Care Systems in Northern and Southern Europe: A Service Mapping Study
A Comparison of Mental Health Care Systems in Northern and Southern Europe: A Service Mapping Study Open
Mental health services (MHS) have gone through vast changes during the last decades, shifting from hospital to community-based care. Developing the optimal balance and use of resources requires standard comparisons of mental health care sy…
View article: Nuorten mielenterveyspalvelut – määrä, tarjonta ja kohdentuminen Uudenmaan alueella
Nuorten mielenterveyspalvelut – määrä, tarjonta ja kohdentuminen Uudenmaan alueella Open
Nuorten pahoinvointi on ollut keskeisenä huolena viimeaikaisessa tutkimuksessa ja julkisessa keskustelussa. Erityisesti lastensuojelun asiakaslapsille kasautuu paljon kuormittavia tekijöitä. Nuoria lähellä olevat palvelut sekä varhainen pu…
View article: Features of borderline personality disorder as a mediator of the relation between childhood traumatic experiences and psychosis-like experiences in patients with mood disorder
Features of borderline personality disorder as a mediator of the relation between childhood traumatic experiences and psychosis-like experiences in patients with mood disorder Open
Background Psychosis-like experiences (PEs) are common in patients with non-psychotic disorders. Several factors predict reporting of PEs in mood disorders, including mood-associated cognitive biases, anxiety and features of borderline per…
View article: A Comparison of Mental Health Care Systems in Northern and Southern Europe: A Service Mapping Study
A Comparison of Mental Health Care Systems in Northern and Southern Europe: A Service Mapping Study Open
Mental health services (MHS) have gone through vast changes during the last decades, shifting from hospital to community-based care. Developing the optimal balance and use of resources requires standard comparisons of mental health care sy…
View article: Therapeutic alliance in guided internet therapy programs for depression and anxiety disorders – A systematic review
Therapeutic alliance in guided internet therapy programs for depression and anxiety disorders – A systematic review Open
View article: Level of functioning, perceived work ability, and work status among psychiatric patients with major mental disorders
Level of functioning, perceived work ability, and work status among psychiatric patients with major mental disorders Open
Background: Major mental disorders are highly disabling conditions that result in substantial socioeconomic burden. Subjective and objective measures of functioning or ability to work, their concordance, or risk factors for them may differ…
View article: Mediating role of borderline personality disorder traits in the effects of childhood maltreatment on suicidal behaviour among mood disorder patients
Mediating role of borderline personality disorder traits in the effects of childhood maltreatment on suicidal behaviour among mood disorder patients Open
Background: Substantial evidence supports an association between childhood maltreatment and suicidal behaviour. However, few studies have examined factors mediating this relationship among patients with unipolar or bipolar mood disorders. …
View article: A Mediation Analysis of Childhood Maltreatment and Suicidal Behavior among Patients with Depressive or Bipolar Disorders
A Mediation Analysis of Childhood Maltreatment and Suicidal Behavior among Patients with Depressive or Bipolar Disorders Open
Introduction Substantial evidence supports association between childhood maltreatment and suicidal behaviour, however, a limited number of studies have examined psychological mechanisms mediating the relationship among patients with mood d…
View article: Self-reported psychosis-like experiences in patients with mood disorders
Self-reported psychosis-like experiences in patients with mood disorders Open
Background: Self-reported psychosis-like experiences (PEs) may be common in patients with mood disorders, but their clinical correlates are not well known. We investigated their prevalence and relationships with self-reported symptoms of d…
View article: Muutokset aikuisten ympärivuorokautisissa mielenterveyspalveluissa HUS-alueella 2012–2014
Muutokset aikuisten ympärivuorokautisissa mielenterveyspalveluissa HUS-alueella 2012–2014 Open
Lähtökohdat
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\nPsykiatrian sairaansijojen vähetessä mielenterveyskuntoutujille suunnatut asumispalvelut ovat lisääntyneet.
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\nAineisto ja menetelmät
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\nHelsingin ja Uudenmaan sairaanhoitopiirin (HUS) kunnissa …
View article: Kannattaako skitsofreniapotilaan masennuslääkitys
Kannattaako skitsofreniapotilaan masennuslääkitys Open
View article: Relationships between self-reported childhood traumatic experiences, attachment style, neuroticism and features of borderline personality disorders in patients with mood disorders
Relationships between self-reported childhood traumatic experiences, attachment style, neuroticism and features of borderline personality disorders in patients with mood disorders Open
View article: Regional Correlates of Psychiatric Inpatient Treatment
Regional Correlates of Psychiatric Inpatient Treatment Open
Current reforms of mental health and substance abuse services (MHS) emphasize community-based care and the downsizing of psychiatric hospitals. Reductions in acute and semi-acute hospital beds are achieved through shortened stays or by avo…
View article: Add-on mirtazapine improves orgasmic functioning in patients with schizophrenia treated with first-generation antipsychotics
Add-on mirtazapine improves orgasmic functioning in patients with schizophrenia treated with first-generation antipsychotics Open
Add-on mirtazapine appears to relieve orgasmic dysfunction in FGA-treated patients with schizophrenia.