Explanipedia

Cathepsin B‐Responsive Dendronized‐Hyaluronic Acid Nanomedicine for Simultaneous Cancer Theranostics Open

Chunhua Guo, Yujun Zeng, Yuan Ou, Zhongwei Gu, Kui Luo · 2025

Tumor microenvironment‐responsive imaging‐guided therapy has emerged as a novel approach for malignant tumor prognosis and therapy. A multifunctional nanoscale drug delivery system is often employed to realize diagnosis, treatment, monitor…

SocioHGN: A Heterogeneous Graph Networks Augmented by Social Mechanism Open

Zhongwei Gu, Pengfei Shen, Hao Chen · 2025

Analyzing online opinion dynamics during controversial global events presents significant challenges. While existing graph learning models identify structural patterns, they overlook key social mechanisms like collective meaning formation …

SocioHGN: A Heterogeneous Graph Network Augmented by Social Mechanism Open

Zhongwei Gu, Pengfei Shen, Hao Chen · 2025

Analyzing online opinion dynamics during controversial global events presents significant challenges. While existing graph learning models identify structural patterns, they overlook key social mechanisms like collective meaning formation …

Correction to “Homomultivalent Polymeric Nanotraps Disturb Lipid Metabolism Homeostasis and Tune Pyroptosis in Cancer” Open

Jie Zhou, Jiecheng Ji, Xue Li, Yuxin Zhang, Lei Gu , et al. · 2025

A self-adhesive hierarchical nanofiber patch for dynamic and multistage management of full-thickness cutaneous wounds Open

Lihuang Wu, Yuqi Wang, Xinyue Zhao, Tingting Zhao, Junhua Li , et al. · 2025

A Study on Evanescent Wave Humidity Sensor Based on PEG-PMMA Microspheres With Enhanced Performance Open

Yuxin Chen, Yutong Qi, Bao Zhu, Xingchen Zhou, Xuefei Xiao , et al. · 2025

In this study, we demonstrate fabrication of an evanescent wave fiber optic humidity sensor based on PEG-PMMA microsphere film as moisture-sensitive material. A three dimensional stacking structure of PEG-PMMA microspheres is formed by dip…

Supramolecular Biomimetic Topology: Macrophage-Engaged Neoadjuvant Platform for Preoperative Immunotherapy Open

Huayu Wu, Dan Zhong, Zhongwei Gu · 2025

The persistent immunosuppression and spatial heterogeneity of advanced solid tumors necessitate next-generation neoadjuvant platforms capable of reprogramming tumor microenvironments while overcoming resistance to immune checkpoint blockad…

Supramolecular Biomimetic Topology: Macrophage-Engaged Neoadjuvant Platform for Preoperative Immunotherapy Open

Huayu Wu, Dan Zhong, Zhongwei Gu · 2025

The persistent immunosuppression and spatial heterogeneity of advanced solid tumors necessitate next-generation neoadjuvant platforms capable of reprogramming tumor microenvironments while overcoming resistance to immune checkpoint blockad…

Bioreducible Nanocapsules for Folic Acid-Assisted Targeting and Effective Tumor-Specific Chemotherapy [Corrigendum] Open

Qiangying Yi, Jin Ma, Ke Kang, Zhongwei Gu · 2025

[This corrects the article DOI: 10.2147/IJN.S149458.].

Unveiling the Dynamics of Collective Recycling Insights from a Large-Scale Educational Recycling Project in Urban China Open

Yulin Gong, Yuxin Su, Siqin Wang, Zhongwei Gu, Yitong Zhu · 2025

A Novel Fluorescent Probe for Dual Mode Detection of Biogenic Amines and its Application: Real-Time Visual Monitoring of Meat Freshness Open

Jiawei Han, Mengyuan Tang, Zhongwei Gu, Chenlei Sun, Jiawei Han , et al. · 2025

Nucleophilic Addition Triggered Fluorescent Probe for Detection of Diphenyl Chlorophosphate (Dcpp): Real Time Application in Monitoring the Presence of Trace Amounts in the Environment Open

Xiaoqian Liu, Yang Yang, Zhongwei Gu, Haiyang Cui, Jiawei Han , et al. · 2025

Exploration of Bacterial Community Structure Profiling and Functional Characteristics in the Vermicomposting of Wasted Sludge and Kitchen Waste Open

Zhongwei Gu, Lei He, Tao Liu, Meiyan Xing, Leiyu Feng , et al. · 2024

Nowadays, the enormously growing amount of kitchen waste and wasted sludge has greatly received global attention. Vermicomposting has been represented as an eco-friendly and sustainable alternative for organic waste management. This study …

Branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status to boost anti-PD-L1 antibody therapy Open

Zhilin Li, Qianfeng Zhang, Zhiqian Li, Long Ren, Dayi Pan , et al. · 2024

Correction: Multiple pH responsive zwitterionic micelles for stealth delivery of anticancer drugs Open

Jin Ma, Ke Kang, Qiangying Yi, Zhirong Zhang, Zhongwei Gu · 2024

Correction for ‘Multiple pH responsive zwitterionic micelles for stealth delivery of anticancer drugs’ by Jin Ma et al. , RSC Adv. , 2016, 6 , 64778–64790, https://doi.org/10.1039/C6RA11645K.

Virus Mimicking Liposomes Incorporated Microneedles Delivery Platform for Efficient Skin Penetration and Enhanced Cellular Uptake Open

Wenyuan Liu, Bo Hou, Dewei Ma, Mingwei Peng, Hongli Mao , et al. · 2024

Preparation of 4A zeolite modified enteromorpha biochar and its application in bacillus thuringiensis microspheres Open

Y. F. Liu, Ming Hui Gao, J. X. Liu, Yaoyu Zhan, Zhongwei Gu , et al. · 2024

The Enteromorpha prolifera biochar and 4A zeolite-modified biochar based on different pyrolysis temperatures were prepared. The biochar of good biocompatibility with Bt was selected by studying the effects of different biochar on the survi…

Engineering Innovative Pullulan-Hyaluronan Water-Soluble Packaging Films for Fast-Disintegrating Hard Capsules Open

Jiliang Song, Fengyu Dai, Zhuohao Gu, Yi Chen, Lanying Li , et al. · 2024

Acid and Crosslinker-Free Self-Assembly Chitosan-Based Sponge with Expandable Property for Hemostasis and Wound Healing Open

Shujun Cao, Peihong Ji, Lili Hao, Hongli Mao, Zhongwei Gu · 2024

Accelerating Disintegration Time of Vegetable Pullulan Capsules Via Phenylboronic Ester Crosslinks Open

Yiyan He, Jiliang Song, Yi Chen, Zhuohao Gu, Fengyu Dai , et al. · 2024

Unraveling Ros Conversion Through Enhanced Enzyme‐Like Activity with Copper‐Doped Cerium Oxide for Tumor Nanocatalytic Therapy Open

Zhengxiang Gu, Dan Zhong, Xingyu Hou, Xuelian Wei, Caikun Liu , et al. · 2023

Nanozyme catalytic therapy for cancer treatments has become one of the heated topics, and the therapeutic efficacy is highly correlated with their catalytic efficiency. In this work, three copper‐doped CeO 2 supports with various structure…

Enzyme‐Responsive Branched Glycopolymer‐Based Nanoassembly for Co‐Delivery of Paclitaxel and Akt Inhibitor toward Synergistic Therapy of Gastric Cancer Open

Xiao-Hai Song, Hao Cai, Zhaochen Shi, Zhiqian Li, Xiuli Zheng , et al. · 2023

Combined chemotherapy and targeted therapy holds immense potential in the management of advanced gastric cancer (GC). GC tissues exhibit an elevated expression level of protein kinase B (AKT), which contributes to disease progression and p…

Enhancing drug penetration in solid tumors via nanomedicine: Evaluation models, strategies and perspectives Open

Dayi Pan, Qiyong Gong, Zhongwei Gu, Kui Luo · 2023

Modulating tumor-stromal crosstalk via a redox-responsive nanomedicine for combination tumor therapy Open

Yuxin Zhang, Jie Zhou, Xiaoting Chen, Zhiqian Li, Lei Gu , et al. · 2023

Enzyme-triggered deep tumor penetration of a dual-drug nanomedicine enables an enhanced cancer combination therapy Open

Lei Gu, Zhenyu Duan, Xue Li, Xin Li, Yinggang Li , et al. · 2023

Cancer cells could be eradicated by promoting generation of excessive intracellular reactive oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and poor penetration of nanomedicines often lead to diverse levels o…

Stimuli-activatable nanomedicine meets cancer theranostics Open

Haonan Li, Feng Yue, Qiang Luo, Zhiqian Li, Xue Li , et al. · 2023

Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics. Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine could be self-assembled, disassembled, or functionally activa…

Customizing Biomimetic Surface Attributes of Dendritic Lipopeptide Nanoplatforms for Extended Circulation Open

Jingjing Wei, Yin Zhou, Yiyan He, Wentao Zhao, Zhiqiang Luo , et al. · 2023

Peptide-Dendrimer-Reinforced Bioinks for 3D Bioprinting of Heterogeneous and Biomimetic in Vitro Models Open

Ke Zhou, Rongjian Ding, Xiwang Tao, Yuwen Cui, Jiquan Yang , et al. · 2023

Co–Assembly of Polymeric Conjugates Sensitizes Neoadjuvant Chemotherapy of Tnbc with Reduced Systemic Toxicity Open

Long Ren, Qian‐Feng Zhang, Wenjia Wang, Xiaoting Chen, Zhiqian Li , et al. · 2023

A Facile Bioorthogonal Chemistry-Based Reversible to Irreversible Strategy to Surmount the Dilemma between Injectability and Stability of Hyaluronic Acid Hydrogels Open

Ming Yuan, Shuangshuang Xu, Yin Zhou, Yi Chen, Jiliang Song , et al. · 2023

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