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View article: The role of cuproptosis in the occurrence and development of gastric cancer
The role of cuproptosis in the occurrence and development of gastric cancer Open
Gastric cancer has emerged as a major global public health threat due to its high incidence and mortality rates. Despite advances in diagnostic and therapeutic approaches, treatment outcomes remain unsatisfactory with frequent disease recu…
View article: Reservoir computing utilizing <scp> HfO <sub>2</sub> </scp> ‐based ferroelectric neuromorphic devices with <scp> WO <sub> <i>x</i> </sub> </scp> nano insertion layers for efficient speech recognition
Reservoir computing utilizing <span> HfO <sub>2</sub> </span> ‐based ferroelectric neuromorphic devices with <span> WO <sub> <i>x</i> </sub> </span> nano insertion layers for efficient speech recognition Open
Reservoir computing (RC) presents a computationally efficient alternative to conventional recurrent neural networks (RNNs) for temporal‐data processing. Traditional bio‐inspired auditory systems often face constraints due to limited comput…
View article: Plant‐Derived Exosome‐Like Nanoparticles: Innovative Nanomedicine for Therapeutic Applications
Plant‐Derived Exosome‐Like Nanoparticles: Innovative Nanomedicine for Therapeutic Applications Open
Plant‐derived exosome‐like nanoparticles (PELNs) have demonstrated substantial potential and promising prospects in the realms of disease prevention and therapy. Composed of a diverse array of bioactive constituents and secondary metabolit…
View article: Test mass charge management in the detection of gravitational waves in space based on UV micro-LED
Test mass charge management in the detection of gravitational waves in space based on UV micro-LED Open
As an alternative to the ultraviolet light emitting diode(UV LED), the feasibility of utilizing UV micro-LED in the charge management in the detection of gravitational waves in space is experimentally studied. Compared with UV LED, micro-L…
View article: Research on degradation characteristics of 253 nm AlGaN-based micro-LEDs for charge management application
Research on degradation characteristics of 253 nm AlGaN-based micro-LEDs for charge management application Open
Ultraviolet-C micro-light-emitting diodes (UVC micro-LEDs) are promising as a superior alternative to existing UV light sources for charge management in the aspect of gravitational wave detection due to their better performance. However, t…
View article: Test Mass Charge Management in the Detection of Gravitational Waves in Space Based on Ultraviolet Micro-Light-Emitting Diode
Test Mass Charge Management in the Detection of Gravitational Waves in Space Based on Ultraviolet Micro-Light-Emitting Diode Open
As an alternative to the ultraviolet light-emitting diode (UV LED), the feasibility of utilizing UV micro-LED in the charge management in the detection of gravitational waves in space is experimentally studied. Compared with UV LED, micro-…
View article: cGAS/STING pathway and gastrointestinal cancer: Mechanisms and diagnostic and therapeutic targets (Review)
cGAS/STING pathway and gastrointestinal cancer: Mechanisms and diagnostic and therapeutic targets (Review) Open
The health of individuals is seriously threatened by intestinal cancer, which includes pancreatic, colorectal, esophageal, gastric and gallbladder cancer. Most gastrointestinal cancers do not have typical and specific early symptoms, and l…
View article: <scp>3D MR</scp> fingerprinting for dynamic contrast‐enhanced imaging of whole mouse brain
<span>3D MR</span> fingerprinting for dynamic contrast‐enhanced imaging of whole mouse brain Open
Purpose Quantitative MRI enables direct quantification of contrast agent concentrations in contrast‐enhanced scans. However, the lengthy scan times required by conventional methods are inadequate for tracking contrast agent transport dynam…
View article: Numerical simulation of deep ultraviolet LED, micro-LED, and nano-LED with different emission wavelengths based on FDTD
Numerical simulation of deep ultraviolet LED, micro-LED, and nano-LED with different emission wavelengths based on FDTD Open
The current low external quantum efficiency (EQE) of deep ultraviolet (DUV) LEDs and micro-LEDs is largely attributed to their low light extraction efficiency (LEE). To address this issue and increase the LEE of DUV devices, various strate…
View article: NaMa: Neighbor-Aware Multi-Modal Adaptive Learning for Prostate Tumor Segmentation on Anisotropic MR Images
NaMa: Neighbor-Aware Multi-Modal Adaptive Learning for Prostate Tumor Segmentation on Anisotropic MR Images Open
Accurate segmentation of prostate tumors from multi-modal magnetic resonance (MR) images is crucial for diagnosis and treatment of prostate cancer. However, the robustness of existing segmentation methods is limited, mainly because these m…
View article: Accurate 3D Prediction of Missing Teeth in Diverse Patterns for Precise Dental Implant Planning
Accurate 3D Prediction of Missing Teeth in Diverse Patterns for Precise Dental Implant Planning Open
In recent years, the demand for dental implants has surged, driven by their high success rates and esthetic advantages. However, accurate prediction of missing teeth for precise digital implant planning remains a challenge due to the intri…
View article: Structure-aware registration network for liver DCE-CT images
Structure-aware registration network for liver DCE-CT images Open
Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with …
View article: Transport Pathways and Kinetics of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI
Transport Pathways and Kinetics of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI Open
Background: Recent studies have suggested the glymphatic system as a solute transport pathway and waste removal mechanism in the brain. Imaging intracisternally administered tracers provides the opportunity of assessing various aspects of …
View article: Transport Pathways and Kinetics of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI
Transport Pathways and Kinetics of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI Open
Recent studies have suggested the glymphatic system as a key mechanism of waste removal in the brain. Dynamic contrast-enhanced MRI (DCE-MRI) using intracisternally administered contrast agents is a promising tool for assessing glymphatic …
View article: A Novel Unified Conditional Score-based Generative Framework for Multi-modal Medical Image Completion
A Novel Unified Conditional Score-based Generative Framework for Multi-modal Medical Image Completion Open
Multi-modal medical image completion has been extensively applied to alleviate the missing modality issue in a wealth of multi-modal diagnostic tasks. However, for most existing synthesis methods, their inferences of missing modalities can…
View article: Learning towards Synchronous Network Memorizability and Generalizability for Continual Segmentation across Multiple Sites
Learning towards Synchronous Network Memorizability and Generalizability for Continual Segmentation across Multiple Sites Open
In clinical practice, a segmentation network is often required to continually learn on a sequential data stream from multiple sites rather than a consolidated set, due to the storage cost and privacy restriction. However, during the contin…
View article: Three‐dimensional high‐resolution T<sub>1</sub> and T<sub>2</sub> mapping of whole macaque brain at 9.4 T using magnetic resonance fingerprinting
Three‐dimensional high‐resolution T<sub>1</sub> and T<sub>2</sub> mapping of whole macaque brain at 9.4 T using magnetic resonance fingerprinting Open
Purpose Quantitative T 1 and T 2 mapping in non‐human primates with whole‐brain coverage is challenged by the requirement of sub‐millimeter resolution and the inhomogeneity of the transmit magnetic field (B 1 + ) covering a large field of …
View article: Dynamic oxygen‐17 MRI with adaptive temporal resolution using golden‐means‐based 3D radial sampling
Dynamic oxygen‐17 MRI with adaptive temporal resolution using golden‐means‐based 3D radial sampling Open
Purpose The aim of this study was to develop a high‐resolution 3D oxygen‐17 ( 17 O) MRI method to delineate the kinetics of 17 O‐enriched water (H 2 17 O) across the entire mouse brain after a bolus injection via the tail vein. Methods The…
View article: Quantification of creatine kinase reaction rate in mouse hindlimb using phosphorus‐31 magnetic resonance spectroscopic fingerprinting
Quantification of creatine kinase reaction rate in mouse hindlimb using phosphorus‐31 magnetic resonance spectroscopic fingerprinting Open
The goal of this study was to evaluate the accuracy, reproducibility, and efficiency of a 31 P magnetic resonance spectroscopic fingerprinting ( 31 P‐MRSF) method for fast quantification of the forward rate constant of creatine kinase (CK)…
View article: High-Resolution Dynamic <sup>31</sup>P-MR Spectroscopic Imaging for Mapping Mitochondrial Function
High-Resolution Dynamic <sup>31</sup>P-MR Spectroscopic Imaging for Mapping Mitochondrial Function Open
Abnormal mitochondrial metabolism is a key cellular dysfunction in many prevalent diseases such as diabetes and heart disease; however, current understanding of mitochondrial function is mostly gained from studies on isolated mitochondria …
View article: Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Imaging
Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Imaging Open
One of the greatest challenges in nanomedicine is the low efficiency with which nanoparticles are delivered to lesions such as tumors in vivo. Here, we show that Physalis mottle virus (PhMV)-like nanoparticles can be developed as bimodal c…
View article: Assessing tissue metabolism by phosphorous-31 magnetic resonance spectroscopy and imaging: a methodology review
Assessing tissue metabolism by phosphorous-31 magnetic resonance spectroscopy and imaging: a methodology review Open
Many human diseases are caused by an imbalance between energy production and demand. Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) provide the unique opportunity for in vivo assessment of several fundamental ev…
View article: Dysprosium-Modified Tobacco Mosaic Virus Nanoparticles for Ultra-High-Field Magnetic Resonance and Near-Infrared Fluorescence Imaging of Prostate Cancer
Dysprosium-Modified Tobacco Mosaic Virus Nanoparticles for Ultra-High-Field Magnetic Resonance and Near-Infrared Fluorescence Imaging of Prostate Cancer Open
The increasing prevalence of ultra-high-field magnetic resonance imaging (UHFMRI) in biomedical research and clinical settings will improve the resolution and diagnostic accuracy of MRI scans. However, better contrast agents are needed to …