Guang-Shen Chiu
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View article: Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2
Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2 Open
View article: Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2
Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2 Open
Cancer cells reprogram their glucose metabolic pathway from oxidative phosphorylation toward aerobic glycolysis. Pyruvate kinase M2 (PKM2), which converts phosphoenolpyruvate (PEP) to pyruvate, is considered the rate-limiting enzyme involv…