Guanghao Chen
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View article: Lineage plasticity and signal dysregulation define the cellular trajectory of osteoarthritis progression
Lineage plasticity and signal dysregulation define the cellular trajectory of osteoarthritis progression Open
This study aims to explore the plastic changes in cell lineages during the progression of osteoarthritis (OA) and their relationship with dysregulation of signaling pathways and provide new molecular targets for precise treatment. Single-c…
View article: Target-tunable colorimetric sensor array based with mixed-valence cerium-centered metal-organic framework nanozyme for on-site sensitive detection of pyridaphenthion bioaccumulation in crops
Target-tunable colorimetric sensor array based with mixed-valence cerium-centered metal-organic framework nanozyme for on-site sensitive detection of pyridaphenthion bioaccumulation in crops Open
Pyridaphenthion, as a broad-spectrum insecticide, warrants attention regarding its residue in crops and toxicity. Herein, a mixed-valence cerium-based metal-organic framework (CeMOF) nanozyme was synthesized via in-situ partial oxidation. …
View article: Upcycling of tobacco waste for solid-liquid co-production via hydrothermal treatment: Fuel application and fertilizer investigation
Upcycling of tobacco waste for solid-liquid co-production via hydrothermal treatment: Fuel application and fertilizer investigation Open
View article: The role of three-dimensional reconstruction in partial nephrectomy for ipsilateral multifocal renal tumors: a multicenter retrospective study
The role of three-dimensional reconstruction in partial nephrectomy for ipsilateral multifocal renal tumors: a multicenter retrospective study Open
PURPOSE: This study aims to evaluate the clinical impact of three-dimensional (3D) reconstruction in partial nephrectomy for ipsilateral multifocal renal tumors (MIRTs), focusing on surgical precision, ischemia management, and postoperativ…
View article: Pseudogene pair-based prognostic model reveals LAT as a biomarker of immune response in head and neck squamous cell carcinoma
Pseudogene pair-based prognostic model reveals LAT as a biomarker of immune response in head and neck squamous cell carcinoma Open
A pseudogene pair-based survival prediction model for HNSCC was developed and validated, providing valuable insights for HNSCC treatment. LAT may serve as a novel biomarker for predicting immune response.
View article: Integrating transcriptomic data with metabolic model unravels the electron transfer mechanisms of Methanosarcina barkeri
Integrating transcriptomic data with metabolic model unravels the electron transfer mechanisms of Methanosarcina barkeri Open
Methanogenic archaea, particularly Methanosarcina, are pivotal to the global carbon cycle and renewable energy production due to their versatile metabolic capabilities. Although transcriptomic analysis is widely employed to identify key ge…
View article: Integrated single-cell sequencing for the development of a GJA4-based precision immuno-prognostic model in melanoma
Integrated single-cell sequencing for the development of a GJA4-based precision immuno-prognostic model in melanoma Open
View article: Material intelligence by the convergence of artificial intelligence and robotic platforms
Material intelligence by the convergence of artificial intelligence and robotic platforms Open
View article: Comparable immune escape capacity between KP.2 and other SARS-CoV-2 variants in the central Chinese population after the first COVID-19 booster
Comparable immune escape capacity between KP.2 and other SARS-CoV-2 variants in the central Chinese population after the first COVID-19 booster Open
The neutralisation ability of homologous and heterologous booster vaccinations against the KP.2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. Therefore, we aimed to evaluate the neutralisation of the O…
View article: Optimizing China's Fertility Policies: Strategies Informed by International Practices
Optimizing China's Fertility Policies: Strategies Informed by International Practices Open
This paper mainly discusses how to solve the problem of declining fertility rate in China. On the basis of combing through the current fertility situation in China, it is found that there are problems such as insufficient fertility subsidi…
View article: Dual-functional Blumea balsamifera leaves-derived carbon nano preservative for fresh-cut apples preservation
Dual-functional Blumea balsamifera leaves-derived carbon nano preservative for fresh-cut apples preservation Open
View article: Achieving efficient photo-enzyme coupling via a novel diketone derivative to expand the scope of enzyme action
Achieving efficient photo-enzyme coupling via a novel diketone derivative to expand the scope of enzyme action Open
This study presents a novel visible light‑responsive diketone derivative, 3‑terphthalic acid azoacetylacetone (BDC‑AA), designed to extend fungal laccase (EC 1.10.3.2) catalytic activity. Experimental results show that BDC‑AA binds specifi…
View article: Integrating transcriptomic data with metabolic model unravels the electron transfer mechanisms of <i>Methanosarcina barkeri</i>
Integrating transcriptomic data with metabolic model unravels the electron transfer mechanisms of <i>Methanosarcina barkeri</i> Open
Methanogenic archaea, particularly Methanosarcina , are pivotal to the global carbon cycle and renewable energy production due to their versatile metabolic capabilities. Although transcriptomic analysis is widely employed to identify key g…
View article: Comparable Immune Escape Capacity Between KP.2 and Other SARS-CoV-2 Variants in the Central Chinese Population After the First COVID-19 Booster
Comparable Immune Escape Capacity Between KP.2 and Other SARS-CoV-2 Variants in the Central Chinese Population After the First COVID-19 Booster Open
The neutralisation ability of homologous and heterologous booster vaccinations against the KP.2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We evaluated Omicron variants (XBB.1, JN.1, and KP.2) neutr…
View article: Electron transport properties of heterogeneous interfaces in solid electrolyte interphase on lithium metal anodes
Electron transport properties of heterogeneous interfaces in solid electrolyte interphase on lithium metal anodes Open
In rechargeable batteries, electron transport properties of inorganics in the solid-electrolyte interphase (SEI) critically determine the safety, lifespan and capacity loss of batteries. However, the electron transport properties of hetero…
View article: Integrated Single-Cell Sequencing for the Development of a Gja4-Based Precision Immuno-Prognostic Model in Melanoma
Integrated Single-Cell Sequencing for the Development of a Gja4-Based Precision Immuno-Prognostic Model in Melanoma Open
View article: FANNO: Augmenting High-Quality Instruction Data with Open-Sourced LLMs Only
FANNO: Augmenting High-Quality Instruction Data with Open-Sourced LLMs Only Open
View article: Efficient and Effective Immobilization of Thallium and Organic Dyes from Wastewater by Iron Fabricated Hydrochar Derived from Microalgae Biomass
Efficient and Effective Immobilization of Thallium and Organic Dyes from Wastewater by Iron Fabricated Hydrochar Derived from Microalgae Biomass Open
View article: Upcycling on Tobacco Waste for Solid-Liquid Co-Production Via Hydrothermal Treatment: Fuel Application and Fertilizer Investigation
Upcycling on Tobacco Waste for Solid-Liquid Co-Production Via Hydrothermal Treatment: Fuel Application and Fertilizer Investigation Open
View article: Corrigendum to “Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition” [Ecotoxicol. Environ. Saf. 287 (2024) 117315]
Corrigendum to “Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition” [Ecotoxicol. Environ. Saf. 287 (2024) 117315] Open
View article: Milling Tools Running Status Monitoring for Centrifugal Compressor Impeller with Scarce Samples
Milling Tools Running Status Monitoring for Centrifugal Compressor Impeller with Scarce Samples Open
View article: Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition
Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition Open
Lead (Pb), mercury (Hg), and cadmium (Cd) are prevalent and persistent environmental contaminants, causing detrimental effects on millions of individuals worldwide. Our previous research demonstrated that early-life exposure to low-level P…
View article: Research on the Functional Improvement of Ultra-high Pressure Rice Soaked in Ferulic Acid
Research on the Functional Improvement of Ultra-high Pressure Rice Soaked in Ferulic Acid Open
In today s society, with the rising number of diabetes patients, the project group studied the effect of different concentrations of ferulic acid solution and ultra-high pressure processing on rice quality. The results showed that ultra-hi…
View article: FANNO: Augmenting High-Quality Instruction Data with Open-Sourced LLMs Only
FANNO: Augmenting High-Quality Instruction Data with Open-Sourced LLMs Only Open
Instruction fine-tuning stands as a crucial advancement in leveraging large language models (LLMs) for enhanced task performance. However, the annotation of instruction datasets has traditionally been expensive and laborious, often relying…
View article: Single and joint bioaccumulation and toxicity of isoproturon and cadmium in green algae (Chlamydomonas reinhardtii)
Single and joint bioaccumulation and toxicity of isoproturon and cadmium in green algae (Chlamydomonas reinhardtii) Open
Background Xenobiotics like pesticide isoproturon (IPU) and heavy metal cadmium (Cd) are environmental contaminants posing serious impacts on ecosystem. Understanding their toxic and accumulative processes is crucial to uncover insightful …
View article: Non-Precious Triple-Atom Catalysts with Ultra-High Activity for Electrochemical Reduction of Nitrate to Ammonia: A Dft Screening
Non-Precious Triple-Atom Catalysts with Ultra-High Activity for Electrochemical Reduction of Nitrate to Ammonia: A Dft Screening Open
View article: Thiosulfate-Involved S-N Biotransformation Enables the Long-Term Stability of a Novel Sulfur-Cycle Driven Mainstream Anammox Process
Thiosulfate-Involved S-N Biotransformation Enables the Long-Term Stability of a Novel Sulfur-Cycle Driven Mainstream Anammox Process Open
View article: Sulfur-mediated bacteria outperform glycogen-accumulating organisms in carbon-deficient wastewater: Key role of influent C/S0 ratios
Sulfur-mediated bacteria outperform glycogen-accumulating organisms in carbon-deficient wastewater: Key role of influent C/S0 ratios Open
Biological nutrient (including nitrogen and phosphorus) removal is often hindered by the lack of organic carbon (C) sources, which can result in the excessive growth of glycogen-accumulating organisms (GAOs), even in sulfate-containing was…
View article: Directing entanglement spreading by means of a quantum East/West heterojunction structure
Directing entanglement spreading by means of a quantum East/West heterojunction structure Open
We extend the translationally invariant quantum East model to an inhomogeneous chain with East/West heterojunction structure. In analogy to the quantum diffusion of substantial particles, we observe a cyclic entanglement entropy spreading …
View article: Elucidating the function and potential inhibitory impact of monovalent cations on assessing the biodegradability of organic substrates in biochemical sulfide potential (BSP) assay
Elucidating the function and potential inhibitory impact of monovalent cations on assessing the biodegradability of organic substrates in biochemical sulfide potential (BSP) assay Open