Gu‐Wei Ji
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View article: Application of Cutting-edge Medical Case-based Teaching Method in Graduate Neuroanatomy Education
Application of Cutting-edge Medical Case-based Teaching Method in Graduate Neuroanatomy Education Open
Objective: To evaluate the effectiveness of cutting-edge medical case-based teaching method in graduate neuroanatomy education. Methods: Graduate students enrolled in a neuroanatomy course were divided into two groups: a conventional Case-…
View article: Camrelizumab plus sorafenib or apatinib achieved long-term survival in a patient with hepatocellular carcinoma and an Eastern Cooperative Oncology Group performance status of 3: a case report
Camrelizumab plus sorafenib or apatinib achieved long-term survival in a patient with hepatocellular carcinoma and an Eastern Cooperative Oncology Group performance status of 3: a case report Open
This case may provide preliminary support for the potential use of targeted therapy combined with immune checkpoint inhibitors in patients with HCC and an ECOG performance status of 3.
View article: Acoustic-based machine learning approaches for depression detection in Chinese university students
Acoustic-based machine learning approaches for depression detection in Chinese university students Open
Background Depression is major global public health problems among university students. Currently, the evaluation and monitoring of depression predominantly depend on subjective and self-reported methods. There is an urgent necessity to de…
View article: Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target
Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target Open
Background/Aims: Identifying patients with intrahepatic cholangiocarcinoma (ICC) likely to benefit from immunochemotherapy, the new front-line treatment, remains challenging. We aimed to unveil a novel radiotranscriptomic signature that ca…
View article: Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma
Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma Open
We established an ERS prognostic model that can predict patient prognosis. We also found that ERS is closely related to the TME and is mainly manifested in the interaction between tumor-associated endothelial cells (TAEs) and tumor-associa…
View article: Early identification of hepatocellular carcinoma patients at high-risk of recurrence using the ADV score: a multicenter retrospective study
Early identification of hepatocellular carcinoma patients at high-risk of recurrence using the ADV score: a multicenter retrospective study Open
The ADV score might become a valuable marker for screening patients at high-risk of HCC recurrence with a cut-off value of 5.7 log, which might help surgeons, pathologists, and HCC patients make appropriate clinical decisions.
View article: Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma
Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma Open
Background:Hepatocellular carcinomais one of the most common tumors worldwide. Various factors in the tumor microenvironment can lead to the activation of endoplasmic reticulum stress, thereby affecting the occurrence and development of tu…
View article: Single-cell RNA-sequencing atlas reveals an FABP1-dependent immunosuppressive environment in hepatocellular carcinoma
Single-cell RNA-sequencing atlas reveals an FABP1-dependent immunosuppressive environment in hepatocellular carcinoma Open
Background Single-cell RNA sequencing, also known as scRNA-seq, is a method profiling cell populations on an individual cell basis. It is particularly useful for more deeply understanding cell behavior in a complicated tumor microenvironme…
View article: Translating imaging traits of mass-forming intrahepatic cholangiocarcinoma into the clinic: From prognostic to therapeutic insights
Translating imaging traits of mass-forming intrahepatic cholangiocarcinoma into the clinic: From prognostic to therapeutic insights Open
The progress toward clinical translation of imaging biomarkers for mass-forming intrahepatic cholangiocarcinoma (MICC) is slower than anticipated. Questions remain on the biologic behaviour of MICC underlying imaging traits. In this study,…
View article: Imaging features based on CT and MRI for predicting prognosis of patients with intrahepatic cholangiocarcinoma: a single-center study and meta-analysis
Imaging features based on CT and MRI for predicting prognosis of patients with intrahepatic cholangiocarcinoma: a single-center study and meta-analysis Open
Background To evaluate the prognostic role of imaging features based on CT and MRI in intrahepatic cholangiocarcinoma (ICC). Methods Two hundred and four patients from a single-center database who underwent radical ICC surgery from 2010 to…
View article: A comprehensive framework of the right posterior section for tailored anatomical liver resection based on three-dimensional simulation system
A comprehensive framework of the right posterior section for tailored anatomical liver resection based on three-dimensional simulation system Open
Precise preoperative planning with an individualized surgical approach based on our framework allows safe anatomical liver resections for cases with lesions in the right posterior section.
View article: Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II clinical trial
Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II clinical trial Open
Objective This study aimed to assess the efficacy and safety of camrelizumab plus apatinib in patients with resectable hepatocellular carcinoma (HCC) as neoadjuvant therapy. Methods Initially, 20 patients with HCC were screened and 18 pati…
View article: Development and validation of a gradient boosting machine to predict prognosis after liver resection for intrahepatic cholangiocarcinoma
Development and validation of a gradient boosting machine to predict prognosis after liver resection for intrahepatic cholangiocarcinoma Open
View article: Surgical Strategy for Resecting Hepatocellular Carcinoma in the Caudate Lobe: Isolated or Combined Lobectomy? A Single-Center Study and Meta-Analysis
Surgical Strategy for Resecting Hepatocellular Carcinoma in the Caudate Lobe: Isolated or Combined Lobectomy? A Single-Center Study and Meta-Analysis Open
Zheng-Gang Xu,1– 3,* Fei-Hong Zhang,1– 3,* Dong-Wei Sun,1– 3,* Qi-Tong Zheng,1– 3 Gu-Wei Ji,1– 3 Ke Wang1– 3 1Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 2Key Labo…
View article: Machine Learning to Improve Prognosis Prediction of Early Hepatocellular Carcinoma After Surgical Resection [Corrigendum]
Machine Learning to Improve Prognosis Prediction of Early Hepatocellular Carcinoma After Surgical Resection [Corrigendum] Open
[This corrects the article DOI: 10.2147/JHC.S320172.].
View article: Machine Learning to Improve Prognosis Prediction of Early Hepatocellular Carcinoma After Surgical Resection
Machine Learning to Improve Prognosis Prediction of Early Hepatocellular Carcinoma After Surgical Resection Open
An ML model trained on a large-scale dataset has good predictive performance at individual scale. Such a model is readily integrated into clinical practice and will be valuable in discussing treatment strategies.
View article: Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19+CD24hiCD27+ Breg Cells
Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19+CD24hiCD27+ Breg Cells Open
CD19 + CD24 hi CD27 + memory Breg cells exhibit decreased abundance in patients with chronic graft-versus-host disease (cGVHD) after liver transplantation and produce less IL-10 than those from patients without cGVHD and healthy donors. Du…
View article: <p>Development and Validation of Pre- and Post-Operative Models to Predict Recurrence After Resection of Solitary Hepatocellular Carcinoma: A Multi-Institutional Study</p>
Development and Validation of Pre- and Post-Operative Models to Predict Recurrence After Resection of Solitary Hepatocellular Carcinoma: A Multi-Institutional Study Open
The two models with corresponding user-friendly calculators are useful tools to predict recurrence before and after resection that may facilitate individualized management of solitary HCC.
View article: Machine-learning analysis of contrast-enhanced CT radiomics predicts recurrence of hepatocellular carcinoma after resection: A multi-institutional study
Machine-learning analysis of contrast-enhanced CT radiomics predicts recurrence of hepatocellular carcinoma after resection: A multi-institutional study Open
View article: The proportion of CD19+CD24hiCD27+ regulatory B cells predicts the occurrence of acute allograft rejection in liver transplantation
The proportion of CD19+CD24hiCD27+ regulatory B cells predicts the occurrence of acute allograft rejection in liver transplantation Open
For the first time, our results suggested the potential role of a decreased proportion of circulating mBregs in predicting AR in patients with post liver transplantation.
View article: Middle hepatic vein-oriented hepatectomy for treatment of hepatocellular carcinoma: a preliminary clinical study
Middle hepatic vein-oriented hepatectomy for treatment of hepatocellular carcinoma: a preliminary clinical study Open
View article: Abnormal expression of ANXA2 predicts cholangiocarcinoma's poor prognosis and exacerbates malignancy via activating β-catenin signaling
Abnormal expression of ANXA2 predicts cholangiocarcinoma's poor prognosis and exacerbates malignancy via activating β-catenin signaling Open
View article: Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT Open
Background/Aims: Aberrant expression of Tip60 is associated with progression in many cancers. However, the role of Tip60 in cancer progression remains contradictory. The aim of this study was to investigate the clinical significance, biolo…
View article: A Radiomics Approach Predicts Lymph Node Metastasis and Clinical Outcomes in Intrahepatic Mass-Forming Cholangiocarcinoma
A Radiomics Approach Predicts Lymph Node Metastasis and Clinical Outcomes in Intrahepatic Mass-Forming Cholangiocarcinoma Open
View article: A giant and insidious subphrenic biloma formation due to gallbladder perforation mimicking biliary cystic tumor: A case report
A giant and insidious subphrenic biloma formation due to gallbladder perforation mimicking biliary cystic tumor: A case report Open
Gallbladder perforation (GBP) represents a rare, but potentially life-threatening, complication of acute cholecystitis. GBP is subdivided into three categories whereas the development of biloma is extremely rare. The present case study rep…
View article: miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma
miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma Open
Aim . To investigate the expression of miR-940 in the hepatocellular carcinoma (HCC) and its impact on function and biological mechanism in the HCC cells. Methods . Quantitative RT-PCR analysis was used to quantify miR-940 expression in 46…