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View article: Adoption of a novel biomarker-guided quality improvement treatment bundle for patients with subclinical acute kidney injury after cardiac surgery
Adoption of a novel biomarker-guided quality improvement treatment bundle for patients with subclinical acute kidney injury after cardiac surgery Open
BACKGROUND Evidence-based peri-operative practices can deliver improved patient outcomes, but their benefits may be limited by obstacles to implementation into routine practice. A multicentre randomised controlled trial demonstrated a redu…
View article: Efficient statistical analysis of trial designs: win ratio and related approaches for composite outcomes
Efficient statistical analysis of trial designs: win ratio and related approaches for composite outcomes Open
In randomized controlled clinical trials, composite outcomes are often used to study treatment effects. This approach is popular because it increases the number of observed events, enhancing statistical power while reducing the required pa…
View article: Factors associated with symptom-to-surgery time in patients undergoing surgical repair for acute type A aortic dissection: an exploratory analysis from a prospective cohort study
Factors associated with symptom-to-surgery time in patients undergoing surgical repair for acute type A aortic dissection: an exploratory analysis from a prospective cohort study Open
Objectives The primary objective of this study was to investigate perioperative factors associated with symptom-to-surgery (STS) time in patients diagnosed with hyper-acute aortic dissection (AAD). The secondary objective was to develop a …
View article: Effectiveness of Cardiopulmonary Bypass Priming with Albumin, Gelofusine and Crystalloids with Retrograde Autologous Priming in Preventing Microcirculatory Dysfunction in Patients during Coronary Artery Bypass Graft Surgery - (PRIME) a Double-Blind Randomized Trial
Effectiveness of Cardiopulmonary Bypass Priming with Albumin, Gelofusine and Crystalloids with Retrograde Autologous Priming in Preventing Microcirculatory Dysfunction in Patients during Coronary Artery Bypass Graft Surgery - (PRIME) a Double-Blind Randomized Trial Open
Introduction Cardiopulmonary bypass (CPB) can cause endothelial dysfunction, leading to edema formation, disturbed microcirculatory perfusion, and impaired tissue oxygenation. Together, these factors contribute to organ dysfunction in pati…
View article: National Institute of Academic Anaesthesia (NIAA) research grants: analysis of awardee characteristics and preliminary grant outputs
National Institute of Academic Anaesthesia (NIAA) research grants: analysis of awardee characteristics and preliminary grant outputs Open
NIAA grants were geographically diverse and supported a broad range of research types. Most funded research was published in high-impact journals. However, a notable lack of diversity was observed among applicants, both successful and unsu…
View article: 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery
2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery Open
sponsorship: European Association of Cardiothoracic Anaesthesiology and Intensive Care, and the European Board of Cardiovascular Perfusion, European Association for Cardio-Thoracic Surgery
View article: 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery
2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery Open
The current document presents a revision of the 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery, emerging from a collaborative effort among the EBCP, EACTAIC and EACTS to establish guidance for unified c…
View article: Time critical diagnoses and transfers of patients with acute type A aortic dissection in the <scp>UK</scp> : national audit of current practice*
Time critical diagnoses and transfers of patients with acute type A aortic dissection in the <span>UK</span> : national audit of current practice* Open
Summary Background Type A aortic dissection repair is one of the most common emergency cardiac surgical procedures undertaken in the UK and has a high mortality. Early diagnosis and prompt surgery by an expert cardiac surgical team is cruc…
View article: Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery
Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery Open
IMPORTANCE Supplementing potassium in an effort to maintain high-normal serum concentrations is a widespread strategy used to prevent atrial fibrillation after cardiac surgery (AFACS), but is not evidence-based, carries risks, and is costl…
View article: Cardiac arrest in adult cardiology patients receiving anaesthetic care: analysis from the 7th National Audit Project ( <scp>NAP7</scp> ) of the Royal College of Anaesthetists
Cardiac arrest in adult cardiology patients receiving anaesthetic care: analysis from the 7th National Audit Project ( <span>NAP7</span> ) of the Royal College of Anaesthetists Open
Summary Background The 7th National Audit Project of the Royal College of Anaesthetists studied peri‐operative cardiac arrest because of existing knowledge gaps in this important topic. This applies in particular to cardiology patients rec…
View article: PeriOperative Quality Initiative (POQI) international consensus statement on perioperative arterial pressure management
PeriOperative Quality Initiative (POQI) international consensus statement on perioperative arterial pressure management Open
Arterial pressure monitoring and management are mainstays of haemodynamic therapy in patients having surgery. This article presents updated consensus statements and recommendations on perioperative arterial pressure management developed du…
View article: Comparison between propofol and total inhalational anaesthesia on cardiovascular outcomes following on-pump cardiac surgery in higher-risk patients: a randomised controlled pilot and feasibility study
Comparison between propofol and total inhalational anaesthesia on cardiovascular outcomes following on-pump cardiac surgery in higher-risk patients: a randomised controlled pilot and feasibility study Open
Objectives Myocardial revascularisation and cardiopulmonary bypass (CPB) can cause ischaemia-reperfusion injury, leading to myocardial and other end-organ damage. Volatile anaesthetics protect the myocardium in experimental studies. Howeve…
View article: Comparison between Propofol and Total Inhalational Anaesthesia on Cardiovascular Outcomes Following On-pump Cardiac Surgery in Higher-Risk Patients – A Randomised Controlled Pilot and Feasibility Study
Comparison between Propofol and Total Inhalational Anaesthesia on Cardiovascular Outcomes Following On-pump Cardiac Surgery in Higher-Risk Patients – A Randomised Controlled Pilot and Feasibility Study Open
Objectives Myocardial revascularisation and cardiopulmonary bypass (CPB) can cause ischemia-reperfusion injury, leading to myocardial and other end-organ damage. Volatile anaesthetics protect the myocardium in experimental studies, however…
View article: Cardiac arrest in vascular surgical patients receiving anaesthetic care: an analysis from the 7th National Audit Project ( <scp>NAP7</scp> ) of the Royal College of Anaesthetists
Cardiac arrest in vascular surgical patients receiving anaesthetic care: an analysis from the 7th National Audit Project ( <span>NAP7</span> ) of the Royal College of Anaesthetists Open
Summary The 7th National Audit Project of the Royal College of Anaesthetists studied peri‐operative cardiac arrest in the UK. We report the results of the vascular surgery cohort from the 12‐month case registry, from 16 June 2021 to 15 Jun…
View article: Peri‐operative cardiac arrest: epidemiology and clinical features of patients analysed in the 7th National Audit Project of the Royal College of Anaesthetists
Peri‐operative cardiac arrest: epidemiology and clinical features of patients analysed in the 7th National Audit Project of the Royal College of Anaesthetists Open
Summary The 7th National Audit Project of the Royal College of Anaesthetists studied peri‐operative cardiac arrest in the UK, a topic of importance to patients, anaesthetists and surgeons. Here we report the results of the 12‐month registr…
View article: Peri‐operative cardiac arrest: management and outcomes of patients analysed in the 7th National Audit Project of the Royal College of Anaesthetists
Peri‐operative cardiac arrest: management and outcomes of patients analysed in the 7th National Audit Project of the Royal College of Anaesthetists Open
Summary The 7th National Audit Project of the Royal College of Anaesthetists studied peri‐operative cardiac arrest in the UK, a topic of importance to patients, anaesthetists and surgeons. We report the results of the 12‐month registry pha…
View article: The incidence of potentially serious complications during non‐obstetric anaesthetic practice in the United Kingdom: an analysis from the 7th National Audit Project ( <scp>NAP7</scp> ) activity survey
The incidence of potentially serious complications during non‐obstetric anaesthetic practice in the United Kingdom: an analysis from the 7th National Audit Project ( <span>NAP7</span> ) activity survey Open
Summary Complications and critical incidents arising during anaesthesia due to patient, surgical or anaesthetic factors, may cause harm themselves or progress to more severe events, including cardiac arrest or death. As part of the 7th Nat…
View article: Organisation of <scp>UK</scp> hospitals and anaesthetic departments in the treatment of peri‐operative cardiac arrest: an analysis from the 7th National Audit Project ( <scp>NAP7</scp> ) local co‐ordinator baseline survey
Organisation of <span>UK</span> hospitals and anaesthetic departments in the treatment of peri‐operative cardiac arrest: an analysis from the 7th National Audit Project ( <span>NAP7</span> ) local co‐ordinator baseline survey Open
Summary We report the results of the Royal College of Anaesthetists' 7th National Audit Project organisational baseline survey sent to every NHS anaesthetic department in the UK to assess preparedness for treating peri‐operative cardiac ar…
View article: The 7th National Audit Project ( <scp>NAP7</scp> ) baseline survey of individual anaesthetists: preparedness for and experiences of peri‐operative cardiac arrest
The 7th National Audit Project ( <span>NAP7</span> ) baseline survey of individual anaesthetists: preparedness for and experiences of peri‐operative cardiac arrest Open
Summary The Royal College of Anaesthetists' 7th National Audit Project baseline survey assessed knowledge, attitudes, practices and experiences of peri‐operative cardiac arrests among UK anaesthetists and Anaesthesia Associates. We receive…
View article: Peri‐operative tobacco cessation interventions: a systematic review and meta‐analysis
Peri‐operative tobacco cessation interventions: a systematic review and meta‐analysis Open
Summary Tobacco smoking is associated with a substantially increased risk of postoperative complications. The peri‐operative period offers a unique opportunity to support patients to stop tobacco smoking, avoid complications and improve lo…
View article: Patient characteristics, anaesthetic workload and techniques in the <scp>UK</scp> : an analysis from the 7th National Audit Project ( <scp>NAP7</scp> ) activity survey
Patient characteristics, anaesthetic workload and techniques in the <span>UK</span> : an analysis from the 7th National Audit Project ( <span>NAP7</span> ) activity survey Open
Summary Detailed contemporary knowledge of the characteristics of the surgical population, national anaesthetic workload, anaesthetic techniques and behaviours are essential to monitor productivity, inform policy and direct research themes…
View article: Adverse renal effects associated with cardiopulmonary bypass
Adverse renal effects associated with cardiopulmonary bypass Open
Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal dysfunction, one of the most common complications of this surgical cohort. Acute kidney injury (AKI) is associated with increased short-term morbidity a…