Guillaume Devailly
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View article: The future of systems genetics in farm animal sciences, a route out of the data jungle
The future of systems genetics in farm animal sciences, a route out of the data jungle Open
Farm animal species are under intense selection on relatively small population sizes. Genetic and genomic selection has provided remarkable genetic gains in the last century. Nevertheless, current methods aiming to link genome to phenome i…
View article: Author response of: The future of systems genetics in farm animal sciences, a route out of the data jungle. Round#1
Author response of: The future of systems genetics in farm animal sciences, a route out of the data jungle. Round#1 Open
View article: Travaux autour de la méthylation de l’ADN et de la régulation de l’expression des gènes chez les vertébrés
Travaux autour de la méthylation de l’ADN et de la régulation de l’expression des gènes chez les vertébrés Open
DNA methylation on CpG dinucleotides is involved in the regulation of gene expression and the repression of transposable elements in vertebrates. Methylated cytosines are more mutagenic than other bases in the genome. DNA methylation has l…
View article: The future of systems genetics in farm animal sciences
The future of systems genetics in farm animal sciences Open
Farm animal species are under intense selection on relatively small population sizes. Genetic and genomic selection has provided remarkable genetic gains in the last century. Nevertheless, current methods aiming to link genome to phenome i…
View article: Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression: a pilot study
Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression: a pilot study Open
Climate change, with its repercussions on agriculture, is one of the most important adaptation challenges for livestock production. Poultry production is a major source of proteins for human consumption all over the world. With a growing h…
View article: Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression
Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression Open
Climate change, with its repercussions on agriculture, is one of the most important adaptation challenges for livestock production. Poultry production is a major source of proteins for human consumption all over the world. With a growing h…
View article: Divergent selection for feed efficiency in pigs altered the duodenum transcriptomic response to feed intake and its DNA methylation profiles
Divergent selection for feed efficiency in pigs altered the duodenum transcriptomic response to feed intake and its DNA methylation profiles Open
The duodenum is a key organ for the hunger/satiety loop and nutrient sensing. We investigated how the duodenum transcriptome and DNA methylation profiles are affected by feed intakes in pigs. We observed thousands of changes in gene expres…
View article: Epigénétique, gènes et environnement : quelle importance pour les pratiques d’élevage et les méthodes de sélection des volailles ?
Epigénétique, gènes et environnement : quelle importance pour les pratiques d’élevage et les méthodes de sélection des volailles ? Open
L'épigénétique est communément définie comme l’étude de l'ensemble des mécanismes moléculaires impliqués dans la régulation de l’expression des gènes qui sont réversibles et transmissibles au cours du développement et parfois entre générat…
View article: Disruption of the primocolonizing microbiota alters epithelial homeostasis and imprints stem cells in the colon of neonatal piglets
Disruption of the primocolonizing microbiota alters epithelial homeostasis and imprints stem cells in the colon of neonatal piglets Open
The gut microbiota plays a key role in the postnatal development of the intestinal epithelium. However, the bacterial members of the primocolonizing microbiota driving these effects are not fully identified and the mechanisms underlying th…
View article: Transgenerational epigenetics in quail: whole genome DNA methylation analysis
Transgenerational epigenetics in quail: whole genome DNA methylation analysis Open
View article: Supplementary Figure S3 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S3 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in HEK-293T and HepG2 cells rapidly results in cell cycle blockade in G2/M phases and mitotic catastrophe events.
View article: Supplementary Table S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Table S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
List of all up-regulated genes in Tif1γ-/--primary MEFs compared to control-primary MEFs (fold {greater than or equal to}1.70).
View article: Supplementary Figure S3 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S3 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in HEK-293T and HepG2 cells rapidly results in cell cycle blockade in G2/M phases and mitotic catastrophe events.
View article: Supplementary Table S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Table S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
List of all up-regulated genes in Tif1γ-/--primary MEFs compared to control-primary MEFs (fold {greater than or equal to}1.70).
View article: Supplementary Figure S2 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S2 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in primary mouse embryonic fibroblasts rapidly results in cell cycle blockade in G2/M phases, spindle checkpoint activation and mitotic catastrophe events.
View article: Data from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Data from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
The transcription accessory factor TIF1γ/TRIM33/RFG7/PTC7/Ectodermin functions as a tumor suppressor that promotes development and cellular differentiation. However, its precise function in cancer has been elusive. In the present st…
View article: Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
View article: Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Supplementary Figure Legends from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
View article: Supplementary Figure S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in spontaneously immortalized mouse embryonic fibroblasts rapidly results in cell cycle blockade in G2/M phases, spindle checkpoint activation and mitotic catastrophe events.
View article: Supplementary Methods and References from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Methods and References from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Description of additional methods and procedures used in the study. Also includes Supplementary References.
View article: Data from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Data from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
The transcription accessory factor TIF1γ/TRIM33/RFG7/PTC7/Ectodermin functions as a tumor suppressor that promotes development and cellular differentiation. However, its precise function in cancer has been elusive. In the present st…
View article: Supplementary Figure S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S1 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in spontaneously immortalized mouse embryonic fibroblasts rapidly results in cell cycle blockade in G2/M phases, spindle checkpoint activation and mitotic catastrophe events.
View article: Supplementary Methods and References from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Methods and References from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Description of additional methods and procedures used in the study. Also includes Supplementary References.
View article: Supplementary Figure S2 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Supplementary Figure S2 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability Open
Inactivation of Tif1γ in primary mouse embryonic fibroblasts rapidly results in cell cycle blockade in G2/M phases, spindle checkpoint activation and mitotic catastrophe events.
View article: Divergent selection for feed efficiency in pigs altered the duodenum transcriptome and DNA methylation profiles, resulting in greater responses to feed intake in the most efficient line
Divergent selection for feed efficiency in pigs altered the duodenum transcriptome and DNA methylation profiles, resulting in greater responses to feed intake in the most efficient line Open
Feed efficiency is a trait of interest in pigs as it contributes to lowering the ecological and economical costs of pig production. A divergent genetic selection experiment from a Large White pig population was performed for 10 generations…
View article: Transgenerational epigenetics in quail
Transgenerational epigenetics in quail Open
View article: PANORAMA : PArticipative desigN to enhance OutdooR Access of farM Animals
PANORAMA : PArticipative desigN to enhance OutdooR Access of farM Animals Open
View article: The phenotype of the gut region is more stably retained than developmental stage in piglet intestinal organoids
The phenotype of the gut region is more stably retained than developmental stage in piglet intestinal organoids Open
Intestinal organoids are innovative in vitro tools to study the digestive epithelium. The objective of this study was to generate jejunum and colon organoids from suckling and weaned piglets in order to determine the extent to which organo…
View article: Visualisation of FAANG data with VizFaDa
Visualisation of FAANG data with VizFaDa Open
International audience
View article: Transfection ADN ou ARNm d’organoïdes intestinaux de porc pour une application en édition de l’épigénome
Transfection ADN ou ARNm d’organoïdes intestinaux de porc pour une application en édition de l’épigénome Open
International audience