Guillaume Harlé
YOU?
Author Swipe
View article: Metal centers and aromatic moieties in Schiff base complexes: impact on G-quadruplex stabilization and oncogene downregulation
Metal centers and aromatic moieties in Schiff base complexes: impact on G-quadruplex stabilization and oncogene downregulation Open
We present the synthesis and characterization of novel square planar transition metal complexes of Schiff base ligands, which act as guanine quadruplex binders and stabilizers.
View article: Supplementary Figures 1-12 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Supplementary Figures 1-12 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Supplementary Figures and Legends
View article: Supplementary Table 1 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Supplementary Table 1 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Supplementary Table 1
View article: Data from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Data from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated t…
View article: Supplementary Table 1 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Supplementary Table 1 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Supplementary Table 1
View article: Data from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Data from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated t…
View article: Supplementary Figures 1-12 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Supplementary Figures 1-12 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Supplementary Figures and Legends
View article: The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis
The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis Open
Maintaining iron homeostasis is fundamental for almost all living beings, and its deregulation correlates with severe and debilitating pathologies. The process is made more complicated by the omnipresence of iron and by its role as a funda…
View article: The iron maiden. Cytosolic aconitase/IRP1 conformational transition in the regulation of ferritin translation and iron hemostasis
The iron maiden. Cytosolic aconitase/IRP1 conformational transition in the regulation of ferritin translation and iron hemostasis Open
Maintaining iron homeostasis is fundamental for almost all living being, and its deregulation correlates with severe and debilitating pathologies. The process is made more complicated by the omnipresence of iron and by its role as a fundam…
View article: MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions Open
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated t…
View article: Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity
Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity Open
Lymphatic endothelial cells (LECs) present peripheral tissue antigens to induce T cell tolerance. In addition, LECs are the main source of sphingosine-1-phosphate (S1P), promoting naive T cell survival and effector T cell exit from lymph n…
View article: Lymph Node Stromal Cells: Mapmakers of T Cell Immunity
Lymph Node Stromal Cells: Mapmakers of T Cell Immunity Open
Stromal cells (SCs) are strategically positioned in both lymphoid and nonlymphoid organs to provide a scaffold and orchestrate immunity by modulating immune cell maturation, migration and activation. Recent characterizations of SCs have ex…
View article: Effects of corticosterone injections in mid-to-late mouse postnatal development on adult motor activity and coordination
Effects of corticosterone injections in mid-to-late mouse postnatal development on adult motor activity and coordination Open
View article: Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells
Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells Open
View article: Absence of MHC-II expression by lymph node stromal cells results in autoimmunity
Absence of MHC-II expression by lymph node stromal cells results in autoimmunity Open
How lymph node stromal cells (LNSCs) shape peripheral T-cell responses remains unclear. We have previously demonstrated that murine LNSCs, lymphatic endothelial cells (LECs), blood endothelial cells (BECs), and fibroblastic reticular cells…
View article: Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response
Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response Open
View article: Régulations des systèmes nerveux central et immunitaire en condition de stress : rôle de la corticotropin-releasing hormone et de ses récepteurs
Régulations des systèmes nerveux central et immunitaire en condition de stress : rôle de la corticotropin-releasing hormone et de ses récepteurs Open
In stress conditions, the Hypothalamo-Pituitary-Adrenal (HPA) axis activation leads to an overproduction of glucocorticoïds (such as corticosterone in rodent) by adrenal glands and this activation is well characterized. However, various qu…
View article: Central nervous system and immune system regulation in stress condition: role of corticoprin-releasing hormone ans its receptors
Central nervous system and immune system regulation in stress condition: role of corticoprin-releasing hormone ans its receptors Open