Guillaume Nicolas
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View article: Systematic review and meta‐analysis of the efficacy and safety of [ <sup>177</sup> <scp>Lu</scp> ]Lu‐edotreotide ([ <sup>177</sup> <scp>Lu</scp> ]Lu‐ <scp>DOTATOC</scp> ) for the treatment of neuroendocrine tumors
Systematic review and meta‐analysis of the efficacy and safety of [ <sup>177</sup> <span>Lu</span> ]Lu‐edotreotide ([ <sup>177</sup> <span>Lu</span> ]Lu‐ <span>DOTATOC</span> ) for the treatment of neuroendocrine tumors Open
[ 177 Lu]Lu‐edotreotide is a radiopharmaceutical therapy (RPT) targeting somatostatin receptors, which are commonly overexpressed on neuroendocrine tumors (NETs). This systematic literature review and meta‐analysis describes the efficacy a…
View article: Intravenous iron for iron deficiency in heart failure with preserved ejection fraction. A multivariate analysis
Intravenous iron for iron deficiency in heart failure with preserved ejection fraction. A multivariate analysis Open
View article: First-in-human administration of [61Cu]Cu-NODAGA-LM3 and head-to-head comparison with [68Ga]Ga-DOTA-TOC PET/CT as part of the phase I/II COPPER PET in NET study
First-in-human administration of [61Cu]Cu-NODAGA-LM3 and head-to-head comparison with [68Ga]Ga-DOTA-TOC PET/CT as part of the phase I/II COPPER PET in NET study Open
View article: Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors
Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors Open
Neuroendocrine tumors (NETs) pose a considerable challenge due to their increasing incidence and frequently late-stage diagnosis. The arrival of multikinase inhibitors (MKIs) into clinical practice has brought notable progress in the manag…
View article: <scp>NETest</scp> ® 2.0—A decade of innovation in neuroendocrine tumor diagnostics
<span>NETest</span> ® 2.0—A decade of innovation in neuroendocrine tumor diagnostics Open
Gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are challenging to diagnose and manage. Because there is a critical need for a reliable biomarker, we previously developed the NETest, a liquid biopsy test that quantifies the expr…
View article: Energy assessment during pole vaulting using inertial motion capture: a preliminary study
Energy assessment during pole vaulting using inertial motion capture: a preliminary study Open
View article: Spinal muscular atrophy is also a disorder of spermatogenesis
Spinal muscular atrophy is also a disorder of spermatogenesis Open
Background Spinal muscular atrophy (SMA) patients benefit from pre-mRNA splicing modifiers targeting the SMN2 gene, which aims to increase functional SMN production. The animal toxicity affecting spermatogenesis associated with one such tr…
View article: First-in-human administration of [161Tb]Tb-SibuDAB and comparative dosimetry with standard [177Lu]Lu-PSMA-I&T as part of the PROGNOSTICS phase Ia study
First-in-human administration of [161Tb]Tb-SibuDAB and comparative dosimetry with standard [177Lu]Lu-PSMA-I&T as part of the PROGNOSTICS phase Ia study Open
View article: Énergie de flexion en saut à la perche utilisant la capture de mouvement et la théorie des tige de Kirchhoff-Cosserat
Énergie de flexion en saut à la perche utilisant la capture de mouvement et la théorie des tige de Kirchhoff-Cosserat Open
International audience
View article: Spinal muscular atrophy is also a disorder of spermatogenesis
Spinal muscular atrophy is also a disorder of spermatogenesis Open
Background Spinal muscular atrophy (SMA) patients benefit from pre-mRNA splicing modifiers targeting the SMN2 gene, which aims to increase functional SMN production. The animal toxicity affecting spermatogenesis associated with one such tr…
View article: Dosimetry and pharmacokinetics of [177Lu]Lu-satoreotide tetraxetan in patients with progressive neuroendocrine tumours
Dosimetry and pharmacokinetics of [177Lu]Lu-satoreotide tetraxetan in patients with progressive neuroendocrine tumours Open
Purpose To evaluate the dosimetry and pharmacokinetics of the novel radiolabelled somatostatin receptor antagonist [ 177 Lu]Lu-satoreotide tetraxetan in patients with advanced neuroendocrine tumours (NETs). Methods This study was part of a…
View article: First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum Open
View article: From dry-land to the water: training and testing practices of strength and conditioning coaches in high level French sprint swimmers
From dry-land to the water: training and testing practices of strength and conditioning coaches in high level French sprint swimmers Open
Introduction The aim of this study was to explore training and testing practices from Strength & Conditioning (S&C) coaches who manage groups of high-level French swimmers in elite training centers. The transfer of abilities from d…
View article: Peptide Receptor Radionuclide Therapy Is Effective for Clinical Control of Symptomatic Metastatic Insulinoma: A Long-Term Retrospective Analysis
Peptide Receptor Radionuclide Therapy Is Effective for Clinical Control of Symptomatic Metastatic Insulinoma: A Long-Term Retrospective Analysis Open
Metastatic insulinoma is a rare malignant neuroendocrine tumor characterized by inappropriate insulin secretion, resulting in life-threatening hypoglycemia, which is often difficult to treat. There is currently very limited information abo…
View article: Cell-Free DNA Genomic Profiling and Its Clinical Implementation in Advanced Prostate Cancer
Cell-Free DNA Genomic Profiling and Its Clinical Implementation in Advanced Prostate Cancer Open
Most men with prostate cancer (PCa), despite potentially curable localized disease at initial diagnosis, progress to metastatic disease. Despite numerous treatment options, choosing the optimal treatment for individual patients remains cha…
View article: Associations between load-velocity profiling and race parameters of elite swimmers in the 100 and 200m freestyle events
Associations between load-velocity profiling and race parameters of elite swimmers in the 100 and 200m freestyle events Open
Introduction Improving swimming performance involves assessments of biomechanical variables of the stroke, and it can be achieved using semi-tethered swimming tests. The aim of this study was thus to investigate the associations between lo…
View article: Early response monitoring during [177Lu]Lu-PSMA I&T therapy with quantitated SPECT/CT predicts overall survival of mCRPC patients: subgroup analysis of a Swiss-wide prospective registry study
Early response monitoring during [177Lu]Lu-PSMA I&T therapy with quantitated SPECT/CT predicts overall survival of mCRPC patients: subgroup analysis of a Swiss-wide prospective registry study Open
View article: Long‐term prognosis of fatty‐acid oxidation disorders in adults: Optimism despite the limited effective therapies available
Long‐term prognosis of fatty‐acid oxidation disorders in adults: Optimism despite the limited effective therapies available Open
Introduction Fatty‐acid oxidation disorders (FAODs) are recessive genetic diseases. Materials and methods We report here clinical and paraclinical data from a retrospective study of 44 adults with muscular FAODs from six French reference c…
View article: <sup>61</sup>Cu-Labeled Radiotracers: Alternative or Choice?
<sup>61</sup>Cu-Labeled Radiotracers: Alternative or Choice? Open
View article: Augmented reality for sentinel lymph node biopsy
Augmented reality for sentinel lymph node biopsy Open
Introduction Sentinel lymph node biopsy for oral and oropharyngeal squamous cell carcinoma is a well-established staging method. One variation is to inject a radioactive tracer near the primary tumor of the patient. After a few minutes, au…
View article: A phase I/II study of the safety and efficacy of [177Lu]Lu-satoreotide tetraxetan in advanced somatostatin receptor-positive neuroendocrine tumours
A phase I/II study of the safety and efficacy of [177Lu]Lu-satoreotide tetraxetan in advanced somatostatin receptor-positive neuroendocrine tumours Open
Purpose We present the results of an open-label, phase I/II study evaluating the safety and efficacy of the novel somatostatin receptor (SSTR) antagonist [ 177 Lu]Lu-satoreotide tetraxetan in 40 patients with previously treated, progressiv…
View article: Interdisciplinary Swiss consensus recommendations on staging and treatment of advanced prostate cancer
Interdisciplinary Swiss consensus recommendations on staging and treatment of advanced prostate cancer Open
The management of prostate cancer is undergoing rapid changes in all disease settings. Novel imaging tools for diagnosis have been introduced, and the treatment of high-risk localized, locally advanced and metastatic disease has changed co…
View article: Clinical features and maternal and fetal outcomes in women with Guillain-Barré syndrome in pregnancy
Clinical features and maternal and fetal outcomes in women with Guillain-Barré syndrome in pregnancy Open
View article: Current clinical management of CIDP with immunoglobulins in France: An expert opinion
Current clinical management of CIDP with immunoglobulins in France: An expert opinion Open
Treatment strategies in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) must be adapted on a case-to-case basis. Validated and reproducible tools for monitoring treatment response are required at diagnosis, when initiating…
View article: Changes in electrophysiological findings suggestive of demyelination following <scp>Guillain‐Barré</scp> syndrome: A retrospective study
Changes in electrophysiological findings suggestive of demyelination following <span>Guillain‐Barré</span> syndrome: A retrospective study Open
Introduction/Aims Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is the most common form of Guillain‐Barré syndrome (GBS) in Western countries. However, electrophysiological descriptions of changes in abnormalities suggesti…
View article: The Emergence of Somatostatin Antagonist–Based Theranostics: Paving the Road Toward Another Success?
The Emergence of Somatostatin Antagonist–Based Theranostics: Paving the Road Toward Another Success? Open
International audience
View article: Biomechanical analysis of the final push of an elite springboard diver
Biomechanical analysis of the final push of an elite springboard diver Open
International audience
View article: Méthodologie d’analyse des échanges d’énergie entre le plongeur et le plongeoir
Méthodologie d’analyse des échanges d’énergie entre le plongeur et le plongeoir Open
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View article: Radiolabeled Somatostatin Analogs—A Continuously Evolving Class of Radiopharmaceuticals
Radiolabeled Somatostatin Analogs—A Continuously Evolving Class of Radiopharmaceuticals Open
Somatostatin receptors (SSTs) are recognized as favorable molecular targets in neuroendocrine tumors (NETs) and neuroendocrine neoplasms (NENs), with subtype 2 (SST2) being the predominantly and most frequently expressed. PET/CT imaging wi…
View article: Models and methods for analyzing interaction in springboard diving
Models and methods for analyzing interaction in springboard diving Open
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