Guillem López de Egea
YOU?
Author Swipe
View article: First report of a DIM-1-producing <i>Pseudomonas aeruginosa</i> in Spain: genomic characterization and resistance determinants
First report of a DIM-1-producing <i>Pseudomonas aeruginosa</i> in Spain: genomic characterization and resistance determinants Open
This study reports the first DIM-1-producing Pseudomonas aeruginosa identified in Spain. The multidrug-resistant ST233 clone harbored the bla DIM-1 gene within the class 1 integron In1592, together with aminoglycoside resistance genes aph(…
View article: Effectiveness of the BioFire FilmArray for the rapid detection of bloodstream infection in haematological patients with febrile neutropenia (the ONFIRE study): study protocol of a prospective, multicentre observational study at three reference university hospitals in Spain
Effectiveness of the BioFire FilmArray for the rapid detection of bloodstream infection in haematological patients with febrile neutropenia (the ONFIRE study): study protocol of a prospective, multicentre observational study at three reference university hospitals in Spain Open
Introduction Bloodstream infection (BSI) due to multidrug-resistant Gram-negative bacilli is a serious global health problem that has a profound impact on severely immunosuppressed neutropenic haematological patients. Prompt institution of…
View article: Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations
Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations Open
iSDSE incidence is increasing and associated with older patients with comorbidities. Genetically, SDSE is diverse with a high capacity to integrate MGEs carrying resistance determinants. Mouse model studies showed the enhanced virulence of…
View article: Assessing sepsis-induced immunosuppression to predict positive blood cultures
Assessing sepsis-induced immunosuppression to predict positive blood cultures Open
Introduction Bacteremia is a life-threatening condition that can progress to sepsis and septic shock, leading to significant mortality in the emergency department (ED). The standard diagnostic method, blood culture, is time-consuming and p…
View article: A New Integrative and Mobilizable Element Is a Major Contributor to Tetracycline Resistance in Streptococcus dysgalactiae subsp. equisimilis
A New Integrative and Mobilizable Element Is a Major Contributor to Tetracycline Resistance in Streptococcus dysgalactiae subsp. equisimilis Open
Tetracycline resistance in streptococci is mainly due to ribosomal protection mediated by the tet(M) gene that is usually located in the integrative and conjugative elements (ICEs) of the Tn916-family. In this study, we analyzed the genes …
View article: An Overview of Macrolide Resistance in Streptococci: Prevalence, Mobile Elements and Dynamics
An Overview of Macrolide Resistance in Streptococci: Prevalence, Mobile Elements and Dynamics Open
Streptococcal infections are usually treated with beta-lactam antibiotics, but, in case of allergic patients or reduced antibiotic susceptibility, macrolides and fluoroquinolones are the main alternatives. This work focuses on studying mac…
View article: Deciphering mobile genetic elements disseminating macrolide resistance in <i>Streptococcus pyogenes</i> over a 21 year period in Barcelona, Spain
Deciphering mobile genetic elements disseminating macrolide resistance in <i>Streptococcus pyogenes</i> over a 21 year period in Barcelona, Spain Open
Objectives To phenotypically and genetically characterize the antibiotic resistance determinants and associated mobile genetic elements (MGEs) among macrolide-resistant (MR) Streptococcus pyogenes [Group A streptococci (GAS)] clinical isol…