Guangyu Zhou
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View article: Patterns and trends of medication use among patients with bipolar disorder in Northeast China: A study from a large psychiatric center (2013−2022)
Patterns and trends of medication use among patients with bipolar disorder in Northeast China: A study from a large psychiatric center (2013−2022) Open
In China, manic/hypomanic episodes remained the predominant episode type. Combination therapy, particularly with three medications, was most commonly used for treatment of bipolar disorder patients and the patterns were episode-specific. L…
View article: The Application and Ethical Implication of Generative AI in Mental Health: Systematic Review
The Application and Ethical Implication of Generative AI in Mental Health: Systematic Review Open
Background Mental health disorders affect an estimated 1 in 8 individuals globally, yet traditional interventions often face barriers, such as limited accessibility, high costs, and persistent stigma. Recent advancements in generative arti…
View article: The Relationship Between Self-Compassion and Resilience in the General Population: Protocol for a Systematic Review and Meta-Analysis
The Relationship Between Self-Compassion and Resilience in the General Population: Protocol for a Systematic Review and Meta-Analysis Open
Background Resilience can protect individuals from the negative impact of adversity, facilitating a swift recovery. The exploration of protective factors contributing to resilience has been a central focus of research. Self-compassion, a p…
View article: A longitudinal investigation of mental health outcomes after the <scp>Henan</scp> floods in <scp>China</scp>: Examining predictors of resilience trajectories
A longitudinal investigation of mental health outcomes after the <span>Henan</span> floods in <span>China</span>: Examining predictors of resilience trajectories Open
A heavy rainstorm struck Henan, China, in July 2021. Previous studies have indicated that natural disasters have a wide range of psychological sequelae, but little research has been done on the psychological effects of floods specifically.…
View article: #3798 A MULTICENTER CLINICAL STUDY OF CELLULOSE TRIACETATE MEMBRANES AND POLYSULFONE MEMBRANE DIALYZERS IN MAINTENANCE HEMODIALYSIS PATIENTS
#3798 A MULTICENTER CLINICAL STUDY OF CELLULOSE TRIACETATE MEMBRANES AND POLYSULFONE MEMBRANE DIALYZERS IN MAINTENANCE HEMODIALYSIS PATIENTS Open
Background and Aims With the continuous improvement of dialysis membrane materials, polysulfone (PS) has replaced traditional cellulose membranes with excellent biocompatibility and dominates the market applications. In our clinical work, …
View article: Research on the Application of Beijing Opera Character Modeling in Children’s Picture Books
Research on the Application of Beijing Opera Character Modeling in Children’s Picture Books Open
Children"s understanding and inheritance of traditional Chinese culture and innovation of Chinese children"s picture book art form are of great significance to carry forward traditional culture and strengthen confidence in Chinese culture.…
View article: The influence of physical exercise on college students’ life satisfaction: The chain mediating role of self-control and psychological distress
The influence of physical exercise on college students’ life satisfaction: The chain mediating role of self-control and psychological distress Open
Objective To explore the relationship between physical exercise and life satisfaction among college students and test the dual mediating role of self-control and psychological distress between them. Methods A sample of 526 Chinese college …
View article: Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinoma
Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinoma Open
Background Aberrant DNA methylation may offer opportunities in revolutionizing cancer screening and diagnosis. We sought to identify a non-invasive DNA methylation-based screening approach using cell-free DNA (cfDNA) for early detection of…
View article: Editorial: Recent Advances of Evidence-Based Neuropsychology
Editorial: Recent Advances of Evidence-Based Neuropsychology Open
Neuropsychology stands at the intersection of brain and behavior. This distinctive position gives it the unique opportunity to provide insights into the pathophysiological mechanisms underlying some physical and mental health disorders tha…
View article: COVID-19 Stress and Addictive Social Media Use (SMU): Mediating Role of Active Use and Social Media Flow
COVID-19 Stress and Addictive Social Media Use (SMU): Mediating Role of Active Use and Social Media Flow Open
The ongoing COVID-19 pandemic is likely to enhance the risk of addictive social media use (SMU) as people spend more time online maintaining connectivity when face-to-face communication is limited. Stress is assumed to be a critical predic…
View article: Social Media Use and Mental Health during the COVID‐19 Pandemic: Moderator Role of Disaster Stressor and Mediator Role of Negative Affect
Social Media Use and Mental Health during the COVID‐19 Pandemic: Moderator Role of Disaster Stressor and Mediator Role of Negative Affect Open
Background Informed by the differential susceptibility to media effects model (DSMM), the current study aims to investigate associations of COVID‐19‐related social media use with mental health outcomes and to uncover potential mechanisms u…
View article: Targeting B7-H3 Immune Checkpoint With Chimeric Antigen Receptor-Engineered Natural Killer Cells Exhibits Potent Cytotoxicity Against Non-Small Cell Lung Cancer
Targeting B7-H3 Immune Checkpoint With Chimeric Antigen Receptor-Engineered Natural Killer Cells Exhibits Potent Cytotoxicity Against Non-Small Cell Lung Cancer Open
Chimeric antigen receptor (CAR)-modified natural killer (NK) cell therapy represents a kind of promising anti-cancer treatment because CAR renders NK cells activation and recognition specificity toward tumor cells. An immune checkpoint mol…
View article: Risk Awareness, Self-Efficacy, and Social Support Predict Secure Smartphone Usage
Risk Awareness, Self-Efficacy, and Social Support Predict Secure Smartphone Usage Open
It is widely acknowledged that non-compliance with smartphone security behaviors is widespread and may cause severe harm to people and devices. In addition to device-based security issues, there are psychological factors involved in these …
View article: Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2
Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2 Open
A newly identified novel coronavirus (SARS-CoV-2) is causing pneumonia-associated respiratory syndrome across the world. Epidemiology, genomics, and pathogenesis of the SARS-CoV-2 show high homology with that of SARS-CoV. Current efforts a…
View article: Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing
Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing Open
Chimeric antigen receptor (CAR) T cells have shown great promise in the treatment of hematological and solid malignancies. However, despite the success of this field, there remain some major challenges, including accelerated T cell exhaust…
View article: Combination of Pulsed Radiofrequency withContinuous Radiofrequency Thermocoagulationat Low Temperature Improves Efficacy andSafety in V2/V3 Primary Trigeminal Neuralgia
Combination of Pulsed Radiofrequency withContinuous Radiofrequency Thermocoagulationat Low Temperature Improves Efficacy andSafety in V2/V3 Primary Trigeminal Neuralgia Open
Background: Primary trigeminal neuralgia (TN) is a common clinical refractory neuralgia. Severe pain is experienced during episodes, severely impacting the patient’s quality of life. Long-term suffering from the disease can lead to anxiety…
View article: Disclosure of Same-Sex Behaviors to Health-care Providers and Uptake of HIV Testing for Men Who Have Sex With Men: A Systematic Review
Disclosure of Same-Sex Behaviors to Health-care Providers and Uptake of HIV Testing for Men Who Have Sex With Men: A Systematic Review Open
To promote HIV-testing and offer optimal care for men who have sex with men (MSM), health-care providers (HCPs) must first be aware of their patients’ sexual behaviors. Otherwise, HCPs may overlook MSM’s risks for HIV infection and their s…
View article: The Relationship between Obesity, Sleep and Physical Activity in Chinese Preschool Children
The Relationship between Obesity, Sleep and Physical Activity in Chinese Preschool Children Open
Background: Pediatric overweight and obesity has become a major public health problem in China. The goal of this study is to understand overweight and obesity in preschool children in Changsha City in the context of their sleep and physica…
View article: Why do oncologists hide the truth? Disclosure of cancer diagnoses to patients in China: A multisource assessment using mixed methods
Why do oncologists hide the truth? Disclosure of cancer diagnoses to patients in China: A multisource assessment using mixed methods Open
Objective In the United States and most European countries, cancer diagnoses are disclosed to patients. In China, however, the trend toward full disclosure has progressed slowly. The present study aimed to explore attitudes toward truth‐te…
View article: Hepatitis B Virus X Protein Reduces Podocyte Adhesion via Downregulation of α3β1 Integrin
Hepatitis B Virus X Protein Reduces Podocyte Adhesion via Downregulation of α3β1 Integrin Open
Background/Aims: Hepatitis B virus (HBV)-associated glomerulonephritis (HBV-GN) is characterized by a reduced number of podocytes due to apoptosis and shedding from the basement membrane. However, the pathological mechanism of HBV-GN is un…
View article: Hepatitis B Virus X Protein Modulates Apoptosis in NRK-52E Cells and Activates Fas/FasL Through the MLK3-MKK7-JNK3 Signaling Pathway
Hepatitis B Virus X Protein Modulates Apoptosis in NRK-52E Cells and Activates Fas/FasL Through the MLK3-MKK7-JNK3 Signaling Pathway Open
Background/Aims: The hepatitis B virus X protein (HBx) contributes to HBV-induced injury of renal tubular cells and induces apoptosis via Fas/FasL up-regulation. However, the mechanism of Fas/FasL activation is unknown. Recent studies indi…