Gul-e-Saba Chaudhry
YOU?
Author Swipe
View article: Morpho-Physiological Responses of Selected Vegetables in Hydroponic and Soil-Based Systems Under Climatic Stress
Morpho-Physiological Responses of Selected Vegetables in Hydroponic and Soil-Based Systems Under Climatic Stress Open
An extreme climatic change due to anthropogenic activities causes disruptions in ecosystems and threatens the planet’s overall balance. Hydroponic is smart and sustainable agriculture practice that aims to produce two times more yield than…
View article: DIETARY DETERMINANTS OF HEMOGLOBIN LEVELS AMONG YOUNG ADULTS: EVIDENCE FROM A CROSS-SECTIONAL STUDY
DIETARY DETERMINANTS OF HEMOGLOBIN LEVELS AMONG YOUNG ADULTS: EVIDENCE FROM A CROSS-SECTIONAL STUDY Open
Objectives: Nutrition plays a crucial role throughout all stages of life, but young adulthood is particularly significant for establishing healthy eating habits that can persist into the future. Globally, iron-deficiency anemia stands as t…
View article: Therapeutic Potential of Fabaceae Species: A Phytochemical and Bioactivity Investigation
Therapeutic Potential of Fabaceae Species: A Phytochemical and Bioactivity Investigation Open
Introduction: The increasing prevalence of chronic diseases and infectious ailments necessitates the exploration of novel therapeutic agents. This study aims to elucidate selected Fabaceae species’ phytochemical composition and biological …
View article: The Albizia julibrissin and Caesalpinia decapetala extracts induces potential enzymes and cell growth inhibition via anti-acetylcholinesterase, anti-lipase, anti-glycation and cytotoxicity activity
The Albizia julibrissin and Caesalpinia decapetala extracts induces potential enzymes and cell growth inhibition via anti-acetylcholinesterase, anti-lipase, anti-glycation and cytotoxicity activity Open
Introduction: Medicinal plants are dynamic source of human health because of their therapeutic potential in treating various ailments. This study aimed to determine the anti-acetylcholinesterase, anti-lipase, anti-glycation and anti-cancer…
View article: Synergistic Antiproliferative Activity of Newly Synthesized Benzimidazole-Based Silver(I) Complexes on MCF-7 and T47D Cell Lines, CT-DNA Interactions Supported by Computational Studies
Synergistic Antiproliferative Activity of Newly Synthesized Benzimidazole-Based Silver(I) Complexes on MCF-7 and T47D Cell Lines, CT-DNA Interactions Supported by Computational Studies Open
This article reports the synthesis, characterization, and antitumor properties of newly synthesized benzimidazole-based Ag(I)-(BNHCs) complexes from their proligands. All of the compounds underwent comprehensive characterization using tech…
View article: Proximate and mineral analysis of the mushroom biscuits
Proximate and mineral analysis of the mushroom biscuits Open
Mushroom is a rich source of nutrients and is widely consumed in Asian countries. Biscuits can be easily fortified with mushroom-rich flour to provide convenient foods to supplement protein in the diet. The research study evaluated the pro…
View article: Aaptamine attenuates the action of statin on PCSK9 and LDLR expression as well as LDL-C uptake in human liver cells
Aaptamine attenuates the action of statin on PCSK9 and LDLR expression as well as LDL-C uptake in human liver cells Open
Atherosclerosis is characterized by the buildup of lipid deposits and plaque formation resulting from consistently elevated levels of LDL-cholesterol (LDL-C) in the blood. This study investigates the effects of aaptamine on the regulation …
View article: Cytotoxic effect and apoptotic induction of tricyclohexyltin p-methoxycinnamate on HT-29 colorectal cancer cells: Implications for anticancer therapeutics
Cytotoxic effect and apoptotic induction of tricyclohexyltin p-methoxycinnamate on HT-29 colorectal cancer cells: Implications for anticancer therapeutics Open
Colorectal cancer’s escalating prevalence in Malaysia prompts the exploration of innovative anticancer agents; amidst this backdrop, tricyclohexyltin p-methoxycinnamate emerges as a synthesized organotin complex with unique bioactive prope…
View article: Aaptamine Counteracts Statin-Induced PCSK9 Elevation to Improve LDL Receptor Expression and Cholesterol Uptake
Aaptamine Counteracts Statin-Induced PCSK9 Elevation to Improve LDL Receptor Expression and Cholesterol Uptake Open
Atherosclerosis arises from lipid accumulation and plaque formation, primarily driven by elevated levels of LDL-cholesterol (LDL-C). PCSK9 plays a critical role by degrading LDL receptors (LDL-R), which are responsible for the clearance of…
View article: Advancing Research on Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Scientometric Analysis
Advancing Research on Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Scientometric Analysis Open
Atherosclerosis is characterised by the accumulation of fatty deposits and plaque as a result of a continuously high level of low-density lipoprotein cholesterol (LDL-C) in the blood. The primary objective of this research is to assess the…
View article: Methotrexate-loaded Fe-metal organic frameworks: Synthesis, characterizations, and drug release investigations
Methotrexate-loaded Fe-metal organic frameworks: Synthesis, characterizations, and drug release investigations Open
View article: Comprehensive Review on Mechanistic Insights, Optimal Dosages, and Safety Prospective of Natural Products in Anticancer Therapeutics
Comprehensive Review on Mechanistic Insights, Optimal Dosages, and Safety Prospective of Natural Products in Anticancer Therapeutics Open
Cancer remains a formidable global health challenge, necessitating sustained research efforts to develop innovative and efficacious therapeutic modalities. The exploration of alternative cancer therapies has gained prominence, given the ad…
View article: Cytotoxicity assays for cancer drug screening: methodological insights and considerations for reliable assessment in drug discovery
Cytotoxicity assays for cancer drug screening: methodological insights and considerations for reliable assessment in drug discovery Open
The importance of cytotoxicity assays in in vitro drug discovery investigations has led to their rising profile. Drugs and other substances can disrupt cell membranes, limit protein synthesis, and bind irreversibly to receptors, all of whi…
View article: CCDC 2265862: Experimental Crystal Structure Determination
CCDC 2265862: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2265863: Experimental Crystal Structure Determination
CCDC 2265863: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Combined Multivariate Statistical Techniques and Water Quality Index (WQI) to Evaluate Spatial Variation in Water Quality
Combined Multivariate Statistical Techniques and Water Quality Index (WQI) to Evaluate Spatial Variation in Water Quality Open
In present study, Water Quality Index (WQI) has been assessed of the Rawal Lake which is a major source of drinking water for people in the Federal Capital, Islamabad, and its adjacent city Rawalpindi in Pakistan. For this, the principal c…
View article: Corrigendum: Targeted drug delivery systems: synthesis and <i>in vitro</i> bioactivity and apoptosis studies of gemcitabine-carbon dot conjugates (2020 <i>Biomed. Mater.</i> 15 065004)
Corrigendum: Targeted drug delivery systems: synthesis and <i>in vitro</i> bioactivity and apoptosis studies of gemcitabine-carbon dot conjugates (2020 <i>Biomed. Mater.</i> 15 065004) Open
View article: Review of: "Toxicity of Olea africana in Artemia Salina and Mice"
Review of: "Toxicity of Olea africana in Artemia Salina and Mice" Open
need modification in terms of structure.There is a need to highlight the problem statement of study and results in a precise, concise, and digested form of knowledge.Appreciate the author for raising awareness through conducted studies reg…
View article: Corrigendum: Development of biodegradable thin films for efficient, specific, and controlled delivery of capecitabine (2021 <i>Biomed. Mater.</i> 16 055019)
Corrigendum: Development of biodegradable thin films for efficient, specific, and controlled delivery of capecitabine (2021 <i>Biomed. Mater.</i> 16 055019) Open
View article: The Efficacy of Metformin and Exenatide in Polycystic Ovary Syndrome (PCOS) Patients
The Efficacy of Metformin and Exenatide in Polycystic Ovary Syndrome (PCOS) Patients Open
Introduction: Polycystic Ovary Syndrome (PCOS) is a hormonal disorder that affects 5-10% of women who are their reproductive age. This meta-analysis aims to evaluate the efficacy of metformin and exenatide, respectively, and to compare the…
View article: Iron Deficiency Amongst University Graduates; Prevalence, Diagnosis, and Iron Consumption
Iron Deficiency Amongst University Graduates; Prevalence, Diagnosis, and Iron Consumption Open
Anemia is a worldwide epidemic, and iron deficiency is a leading cause of anemia.We used anthropometric measurements and a multisectioned questionnaire to get as much information about diet as possible.The blood was taken to determine thei…
View article: Cancer and Disease Diagnosis - Biosensor as Potential Diagnostic Tool for Biomarker Detection
Cancer and Disease Diagnosis - Biosensor as Potential Diagnostic Tool for Biomarker Detection Open
Analysis of cancer biomarkers has enormous promise for advancing our molecular understanding of illness and facilitating more precise and timely diagnosis and follow-up care. MicroRNA, exosomes, ctDNA, CTCs, and proteins are only some of t…
View article: Carbon Stock Estimation of Selected Subtropical Broad-Leaved Evergreen Scrub Forest
Carbon Stock Estimation of Selected Subtropical Broad-Leaved Evergreen Scrub Forest Open
This research estimates the carbon stock of the subtropical broad-leaved evergreen scrub forest of Lehtrar, a revenue estate of Kotli Sattian, Rawalpindi, Punjab, Pakistan. A total of six nested co-centric plots of 17.84 m2 each were laid …
View article: Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics
Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics Open
Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the complexity and multi-regulatory cancer progression, cancer is s…
View article: Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies
Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies Open
In the present work, a concise library of 1,3,5-triaryl-2-pyrazolines (2a-2q) was designed and synthesized by employing a multistep strategy, and the newly synthesized compounds were screened for their urease and α-glucosidase inhib…
View article: CCDC 2061050: Experimental Crystal Structure Determination
CCDC 2061050: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2061049: Experimental Crystal Structure Determination
CCDC 2061049: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Characterization and cytotoxicity of low-molecular-weight chitosan and chito-oligosaccharides derived from tilapia fish scales
Characterization and cytotoxicity of low-molecular-weight chitosan and chito-oligosaccharides derived from tilapia fish scales Open
The present study evaluated the physicochemical characterization and cytotoxicity activity of chitosan and chito-oligosaccharides (COSs). The extraction of chitosan and COSs was executed by chemical hydrolysis. The physicochemical characte…
View article: Induction of Apoptosis by Acanthaster planci sp., and Diadema setosum sp., Fractions in Human Cervical Cancer Cell Line, HeLa
Induction of Apoptosis by Acanthaster planci sp., and Diadema setosum sp., Fractions in Human Cervical Cancer Cell Line, HeLa Open
The potent bioactive compounds might be responsible for inducing apoptosis in cancer cells and, thus, the potential to be a successful candidate for exploring upcoming chemotherapeutic drugs.
View article: Xylocarpus Moluccensis Induces Cytotoxicity in Human Hepatocellular Carcinoma HepG2 Cell Line via Activation of the Extrinsic Pathway
Xylocarpus Moluccensis Induces Cytotoxicity in Human Hepatocellular Carcinoma HepG2 Cell Line via Activation of the Extrinsic Pathway Open
Thus, the present study suggests the remarkable potential of active metabolites in the extract of Xylocarpus moluccensis as a future therapeutic agent for the treatment of cancer..