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The Homeostasis-Enrichment-Plasticity (HEP®) Approach for Premature Infants with Developmental Risks: A Pre-Post Feasibility Study Open
Background: The environmental enrichment (EE) framework has inspired several early intervention (EI) approaches. This study evaluated the feasibility, safety, caregiver acceptance, and satisfaction of implementing the HEP Approach interven…
HEP® (Homeostasis-Enrichment-Plasticity) Approach Changes Sensory–Motor Development Trajectory and Improves Parental Goals: A Single Subject Study of an Infant with Hemiparetic Cerebral Palsy and Twin Anemia Polycythemia Sequence (TAPS) Open
Background: Early intervention (EI) for infants identified as being at high risk for cerebral palsy (CP), or who have been diagnosed with it, is critical for promotion of postnatal brain organization. The aim of this study was to explore t…
Tactile stimulation of young WAG/Rij rats prevents development of depression but not absence epilepsy Open
Investigations in Wistar Albino Glaxo from Rijswijk (WAG/Rij) rats that are susceptible to genetic absence epilepsy have demonstrated that environmental modifications affect absence seizures. Previously, we showed that neonatal tactile sti…
Evaluation of Ayres Sensory Integration<sup>®</sup> Intervention on Sensory Processing and Motor Function in a Child with Rubinstein-Taybi Syndrome: A Case Report Open
The Rubinstein-Taybi Syndrome (RSTS) literature is limited about sensory integration, which is a foundational neurological function of the central nervous system that may affect the development of cognitive, social, and motor skills. The a…
Effects of Topical Cyclosporin A Application on Preventing Epineural Scar Formation in Rats: Experimental Study Open
The aim of this study is to evaluate macroscopic, histopathologic and immunohistochemical effects of topical cyclosporin administration on prevention of epineural scar formation in rats.This experimental study was performed in two groups, …
Use of acellular dermal matrix in peripheral nerve reconstruction: an experimental study on rat sciatic nerve defect Open
The results of this study showed that wrapping ADM around nerve grafts resulted in better outcomes with respect to nerve healing.
Quantifying Neurological Examination in 21st Century Open
Background: Current methods used to measure the muscle strength required to achieve plantar flexion may yield highly variable results depending on the perception of the physician conducting the examination because these tests involve subje…
Quantifying Neurological Examination in 21st Century:Yilmaz-Ilbay Plantar Flexion Test, A Reliable Test for Evaluating Plantar Flexion in L5-S1 Disc Herniation Open
Objectives To evaluate a new examination technique that can quantitatively measure plantar flexion in L5-S1 disc herniation. Materials and methods In this study only subjects with L5-S1 disc herniations were included total number of patien…
Neonatal Tactile Stimulation Downregulates Dendritic Spines in Layer V Pyramidal Neurons of the WAG/Rij Rat Somatosensory Cortex Open
Objective. The aim of our study is to examine the effects of neonatal tactile stimulations on the brain structures that previously defined as the focus of epilepsy in the Wistar-Albino-Glaxo from Rijswijk (WAG/Rij) rat brain with genetic a…
Effects of Postnatal Caffeine Exposure on Absence Epilepsy and Comorbid Depression: Results of a Study in WAG/Rij Rats Open
The present study aims to investigate effect of early caffeine exposure on epileptogenesis and occurrence of absence seizures and comorbid depression in adulthood. For this purpose, Wistar Albino Glaxo from Rijswijk (WAG/Rij) rats were enr…
Neonatal Tactile Stimulation Modulates Dendritic Spine Densities in Somatosensory Cortex of Adult WAG/Rij rats Open
Objective: The aim of our study is to examine the effects of neonatal tactile stimulatons on the brain structures that previously defined as the focus of epilepsy in the Wistar-Albino-Glaxo from Rijswijk (WAG/Rij) rat brain with genetic ab…
Neonatal Tactile Stimulation Modulates Dendritic Spine Densities in Somatosensory Cortex of Adult WAG/Rij rats Open
Objective: The aim of our study is to examine the effects of neonatal tactile stimulatons on the brain structures that previously defined as the focus of epilepsy in the Wistar-Albino-Glaxo from Rijswijk (WAG/Rij) rat brain with genetic ab…
Neonatal Tactile Stimulation Modulates Dendritic Spine Densities in Somatosensory Cortex of Adult WAG/Rij rats Open
Background In previous studies, it has been shown that in early developmental period, the high level of tactile stimulations prevent absence epilepsy development and comorbid depression in Wistar-Albino-Glaxo from Rijswijk (WAG/Rij) rats w…
Neonatal Tactile Stimulations Affect Genetic Generalized Epilepsy and Comorbid Depression-Like Behaviors Open
Recent studies suggest that development of absence epilepsy and comorbid depression might be prevented by increased maternal care of the offspring, in which tactile stimulation induced by licking/grooming and non-nutritive contact seem to …
View article: Side-Effects of Convulsive Seizures and Anti-Seizure Therapy on Bone in a Rat Model of Epilepsy
Side-Effects of Convulsive Seizures and Anti-Seizure Therapy on Bone in a Rat Model of Epilepsy Open
The severe sole effects of seizures on the cortical part of bone were reported in our previous study. However, the side effects of anti-epileptic drug therapy on bones has not been differentiated from the effects of the convulsive seizures…