Gulnara Kurmanalina
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View article: Characteristics of the needs of older people in Kazakhstan: a cross-sectional muliticentre study
Characteristics of the needs of older people in Kazakhstan: a cross-sectional muliticentre study Open
Objectives Shrinking caregiver workforces and rising demand among the oldest age groups necessitate urgent healthcare reforms. In Kazakhstan, high fertility sustains population growth, though care pressures are increasing as the share of o…
View article: Chemotherapy-Induced Endothelial Dysfunction: a Bibliometric Analysis of Research Trends from 1994 to 2024
Chemotherapy-Induced Endothelial Dysfunction: a Bibliometric Analysis of Research Trends from 1994 to 2024 Open
Chemotherapy-induced endothelial damage is a complex issue characterized by cardiovascular toxicity and cellular injury. This study aims to analyze primary research areas related to chemotherapy-induced endothelial dysfunction,…
View article: Phase II Cardiac Rehabilitation Under Compulsory Insurance in Kazakhstan: A Five-Year Cohort Analysis of Clinical and Economic Outcomes
Phase II Cardiac Rehabilitation Under Compulsory Insurance in Kazakhstan: A Five-Year Cohort Analysis of Clinical and Economic Outcomes Open
Background/Aim of Study: Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality globally. Cardiac rehabilitation (CR) plays a pivotal role in the recovery of post-acute myocardial infarction (AMI) patients. Despite…
View article: Metabolic syndrome in reproductive age: A cross-sectional study
Metabolic syndrome in reproductive age: A cross-sectional study Open
Background: Obesity and metabolic syndrome (MetS), as components of excess body weight, have reached global epidemic levels. Objective: The study aimed to investigate the features of the MetS course in men and women of reproductive age. Ma…
View article: Misdiagnosis of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus in Primary Care: A Report of Two Cases and Literature Review
Misdiagnosis of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus in Primary Care: A Report of Two Cases and Literature Review Open
The coexistence of heart failure (HF) and type 2 diabetes mellitus (T2DM) is common and poses a serious threat to human health because these diseases have a high degree of commonality at the vascular level. However, the diagnosis of HF in …
View article: Cardiotoxicity of Anthracycline-based Chemotherapy in Breast Cancer Patients: A Case Series
Cardiotoxicity of Anthracycline-based Chemotherapy in Breast Cancer Patients: A Case Series Open
In Kazakhstan, breast cancer (BC) remains the leading cause of cancer morbidity and mortality among women. The presented case series aims to summarize cardiovascular events that resulted in anthracycline-based chemotherapy discontinuation …
View article: Role of Clinical Risk Factors and B-Type Natriuretic Peptide in Assessing the Risk of Asymptomatic Cardiotoxicity in Breast Cancer Patients in Kazakhstan
Role of Clinical Risk Factors and B-Type Natriuretic Peptide in Assessing the Risk of Asymptomatic Cardiotoxicity in Breast Cancer Patients in Kazakhstan Open
The asymptomatic progression of chemotherapy-induced cardiotoxicity poses a significant risk to breast cancer patients. In the present single-center cohort study, a predictive model for evaluating the risk of cardiotoxicity during or by th…
View article: Time to act: the challenge of high incidence of diabetes and prediabetes in patients admitted with different cardiovascular diseases phenotypes
Time to act: the challenge of high incidence of diabetes and prediabetes in patients admitted with different cardiovascular diseases phenotypes Open
Background Limited studies have focused on diagnosing type 2 diabetes mellitus (T2DM) and prediabetes in hospitalized patients with cardiovascular diseases (CVD) with their different phenotypes. In addition, HbA1c levels in patients admitt…
View article: Stratifying breast cancer patients by baseline risk of cardiotoxic complications linked to chemotherapy
Stratifying breast cancer patients by baseline risk of cardiotoxic complications linked to chemotherapy Open
A majority of modern antitumor pharmaceuticals are accompanied by cardiotoxicity. The study aims to present practical approaches to stratifying the baseline risk of antitumor therapies' cardiotoxicity in patients newly diagnosed wit…
View article: Early Diagnosis of Chemotherapy-Linked Cardiotoxicity in Breast Cancer Patients Using Conventional Biomarker Panel: A Prospective Study Protocol
Early Diagnosis of Chemotherapy-Linked Cardiotoxicity in Breast Cancer Patients Using Conventional Biomarker Panel: A Prospective Study Protocol Open
The prognosis of cancer treatment depends on, among other aspects, the cardiotoxicity of chemotherapy. This research aims to create a feasible algorithm for the early diagnosis of antitumor therapy cardiotoxicity in breast cancer patients.…
View article: Epidemiology, clinical and physiological manifestations of dust lung disease in major industrial centers
Epidemiology, clinical and physiological manifestations of dust lung disease in major industrial centers Open
View article: A first approach to identifying cardiotoxic effects of breast cancer chemotherapeutic treatment in Kazakhstan
A first approach to identifying cardiotoxic effects of breast cancer chemotherapeutic treatment in Kazakhstan Open
As known, the clinical efficacy of chemotherapy is limited by the cardiotoxicity of drugs used. The study aimed to clarify cardiotoxic complications of chemotherapy from the Aktobe Medical Center database for 2018-2019.
View article: Impact of Anemia in Pregnant Women on the Neonatal Conditions
Impact of Anemia in Pregnant Women on the Neonatal Conditions Open
Background. One of the most prevalent illnesses in the world is anemia. Anemia in pregnant women has been a pressing obstetric issue for many years and is one of the most common complications of pregnancy in the world, particularly in deve…
View article: Public Health Rehabilition after Acute Myocardial Infarction: a Randomized Controlled Study
Public Health Rehabilition after Acute Myocardial Infarction: a Randomized Controlled Study Open
Background: Cardiovascular diseases (CVD) are the main causes of death worldwide. The incidence of and mortality from CVD in Kazakhstan is greater than in most neighboring countries warranting urgent public health measures related to both …
View article: Diverse functional responses to high glucose by primary and permanent hybrid endothelial cells in vitro
Diverse functional responses to high glucose by primary and permanent hybrid endothelial cells in vitro Open
Various types of human endothelial cells, including human umbilical vein endothelial cells (HUVECs) and the established hybrid EAhy926 cells, are used in experimental research. Here, we compared the biological properties of HUVECs and EAhy…
View article: Role of Vitamin D in Prevention of Metabolic Syndrome and Cardiovascular Diseases
Role of Vitamin D in Prevention of Metabolic Syndrome and Cardiovascular Diseases Open
Objective: About 90% of cardiovascular diseases can be prevented. In recent years, the role of vitamin D in the prevention of cardiovascular disease and components of metabolic syndrome has been actively discussed. The study aimed to inves…
View article: Pain in People with Advanced Dementia: The Opinions of Kazakh Medical Students
Pain in People with Advanced Dementia: The Opinions of Kazakh Medical Students Open
Slawomir Tobis,1 Agnieszka Neumann-Podczaska,2 Lyudmila Yermukhanova,3 Gulnara Sultanova,4 Gulnara Kurmanalina,5 Kerbez Kimatova,3 Marzena Dworacka,6 Katarzyna Wieczorowska-Tobis2 1Department of Occupational Therapy, Poznan University of M…
View article: <p>Pain in People with Advanced Dementia: The Opinions of Kazakh Medical Students</p>
Pain in People with Advanced Dementia: The Opinions of Kazakh Medical Students Open
PURPOSE: The medical students’ attitude toward pain in people with advanced dementia, while constituting an important factor in care, has rarely been assessed to date. The aim of our study was thus to perform such assessment in medical stu…
View article: Infectious endocarditis сomplicated spondilodiscitis
Infectious endocarditis сomplicated spondilodiscitis Open
This publication presents a clinical case of infectious endocarditis in an adult male aged 60, with manifestation of the disease in the form of spondilodiscitis. The presented observation demonstrates the development of onset of infectious…