Gunnar Blumenstock
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View article: Understanding the pathology workforce: motivations, job satisfaction, and training perspectives in Germany
Understanding the pathology workforce: motivations, job satisfaction, and training perspectives in Germany Open
The growing shortage of pathologists and the increasing workload present significant challenges for the field of pathology. To address these challenges, it is crucial to understand what motivates young doctors to enter pathology training a…
View article: The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at <scp>S102</scp> in colorectal cancer patients, stratified by <i>KRAS</i> mutational status and clinicopathological features
The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at <span>S102</span> in colorectal cancer patients, stratified by <i>KRAS</i> mutational status and clinicopathological features Open
Oncoprotein Y‐box‐binding protein‐1 (YB‐1) is involved in all cancer hallmarks. One of the most studied post‐translational modifications of YB‐1 is phosphorylation on Serine 102 (S102), which is involved in cancer progression. KRAS mutatio…
View article: Benefits of Explorative Saccade Training in Patients with Advanced Glaucomatous Visual Field Defects—A Randomized, Placebo-Controlled Study
Benefits of Explorative Saccade Training in Patients with Advanced Glaucomatous Visual Field Defects—A Randomized, Placebo-Controlled Study Open
Purpose: Patients with advanced glaucoma have visual field defects that impair mobility and quality of life (QoL). We aim to determine the effects of exploratory saccade training (EST) in such patients with bilateral overlapping scotomas t…
View article: High iASPP (PPP1R13L) expression is an independent predictor of adverse clinical outcome in acute myeloid leukemia (AML)
High iASPP (PPP1R13L) expression is an independent predictor of adverse clinical outcome in acute myeloid leukemia (AML) Open
Apoptosis-stimulating proteins of p53 (ASPPs) are a family of proteins that modulate key tumor suppressor pathways via direct interaction with p53. Deregulation of these proteins promotes cancer development and impairs sensitivity to syste…
View article: B7-1 and PlGF-1 are two possible new biomarkers to identify fracture-associated trauma patients at higher risk of developing complications: a cohort study
B7-1 and PlGF-1 are two possible new biomarkers to identify fracture-associated trauma patients at higher risk of developing complications: a cohort study Open
View article: The parkin V380L variant is a genetic modifier of Machado–Joseph disease with impact on mitophagy
The parkin V380L variant is a genetic modifier of Machado–Joseph disease with impact on mitophagy Open
View article: Synthetic, non-person related panoramic radiographs created by generative adversarial networks in research, clinical, and teaching applications
Synthetic, non-person related panoramic radiographs created by generative adversarial networks in research, clinical, and teaching applications Open
Synthetic images can be used for university teaching and patient education without relying on patient-related data. They can also be utilized to upscale existing training datasets to improve the accuracy of AI-based diagnostic systems. The…
View article: Smoking increases risk of complication after musculoskeletal surgery: Analysis of single immune parameter to predict complication risk
Smoking increases risk of complication after musculoskeletal surgery: Analysis of single immune parameter to predict complication risk Open
Smoking is the most significant and modifiable risk factor for a range of conditions, including cancer, cardiovascular and respiratory diseases. Furthermore, it significantly reduces bone mass and increases the risk of fragility fractures …
View article: Analysis of Predictors and Risk Factors of Postpolypectomy Syndrome
Analysis of Predictors and Risk Factors of Postpolypectomy Syndrome Open
Background and aims: Postpolypectomy syndrome (PPS) is a relevant adverse event that can appear after polypectomy. Several publications mention postpolypectomy syndrome using different criteria to define it. The aim of this study is to det…
View article: AZU1: a new promising marker for infection in orthopedic and trauma patients?
AZU1: a new promising marker for infection in orthopedic and trauma patients? Open
Early and reliable detection of infection is vital for successful treatment. Serum markers such as C-reactive protein (CRP) and procalcitonin (PCT) are known to increase with a time lag. Azurocidin 1 (AZU1) has emerged as a promising marke…
View article: Corrigendum: GH responsiveness is not correlated to IGF1 P2 promoter methylation in children with Turner syndrome, GHD and SGA short stature
Corrigendum: GH responsiveness is not correlated to IGF1 P2 promoter methylation in children with Turner syndrome, GHD and SGA short stature Open
[This corrects the article DOI: 10.3389/fendo.2022.897897.].
View article: Factors Associated with the COVID-19 Vaccination Status of Higher Education Students: Results of an Online Cross-Sectional Survey at Six Universities in Southwestern Germany
Factors Associated with the COVID-19 Vaccination Status of Higher Education Students: Results of an Online Cross-Sectional Survey at Six Universities in Southwestern Germany Open
This cross-sectional study explored factors associated with the corona virus disease 2019 (COVID-19) vaccination acceptance among higher education students in southwestern Germany. We conducted a cross-sectional online survey at six state-…
View article: GH Responsiveness Is not Correlated to IGF1 P2 Promoter Methylation in Children With Turner Syndrome, GHD and SGA Short Stature
GH Responsiveness Is not Correlated to IGF1 P2 Promoter Methylation in Children With Turner Syndrome, GHD and SGA Short Stature Open
Background The methylation of IGF1 promoter P2 was reported to negatively correlate with serum IGF-1 concentration and rhGH treatment response in children with idiopathic short stature. These findings have not yet been confirmed. Objective…
View article: Central Visual Function and Genotype–Phenotype Correlations in <i>PDE6A</i>-Associated Retinitis Pigmentosa
Central Visual Function and Genotype–Phenotype Correlations in <i>PDE6A</i>-Associated Retinitis Pigmentosa Open
We conclude that the severity of the different disease-causing PDE6A mutations in humans with respect to central visual function may be ranked as follows: c.2053G>A/p.V685M in homozygous state (most severe) > c.998+1G>A/p.? in homozygous s…
View article: Impact of keratoconus stage on outcome after corneal crosslinking
Impact of keratoconus stage on outcome after corneal crosslinking Open
Background This study aimed to analyze if the outcome after corneal crosslinking (CXL) in progressive keratoconus patients depends on the stage at which the procedure is performed. This knowledge would help to improve success of CXL and to…
View article: Impact of Serum Insulin-Like Growth Factor 1 on Hematopoietic Stem Cell Transplantation Outcome in Pediatric Cancer Patients
Impact of Serum Insulin-Like Growth Factor 1 on Hematopoietic Stem Cell Transplantation Outcome in Pediatric Cancer Patients Open
Hematopoietic stem cell transplantation (HSCT) is associated with severe medical complications and variable outcomes depending on the recipient's disease stage and health condition. Biomarkers predicting outcome may have therapeutic releva…
View article: Neurocognitive development in isolated Robin sequence treated with the Tuebingen palatal plate
Neurocognitive development in isolated Robin sequence treated with the Tuebingen palatal plate Open
View article: Prevalence of <i>Candida species</i> in Psoriasis
Prevalence of <i>Candida species</i> in Psoriasis Open
Background Psoriasis patients are more frequently colonised with Candida species . The correlation between fungal colonisation and clinical severity is unclear, but may exacerbate psoriasis and the impact of antipsoriatic therapies on the …
View article: Impact of Keratoconus Stage on Outcome After Corneal Crosslinking
Impact of Keratoconus Stage on Outcome After Corneal Crosslinking Open
Background: This study aimed to analyze if the outcome after corneal crosslinking (CXL) in progressive keratoconus patients depends on the stage in which the procedure is performed. This knowledge would help to improve success of CXL and f…
View article: Can follow up lung ultrasound in Coronavirus Disease-19 patients indicate clinical outcome?
Can follow up lung ultrasound in Coronavirus Disease-19 patients indicate clinical outcome? Open
Purpose To evaluate whether there is a change in findings of coronavirus disease 2019 patients in follow up lung ultrasound and to determine whether these findings can predict the development of severe disease. Materials and methods In thi…
View article: Outcomes after Descemet membrane endothelial keratoplasty over a period of 7 years at a tertiary referral center: endothelial cell density, central corneal thickness, and visual acuity
Outcomes after Descemet membrane endothelial keratoplasty over a period of 7 years at a tertiary referral center: endothelial cell density, central corneal thickness, and visual acuity Open
View article: Specific Point-of-Care Testing of Coagulation in Patients Treated with Dabigatran
Specific Point-of-Care Testing of Coagulation in Patients Treated with Dabigatran Open
Background and Purpose Accurate and rapid assessment of coagulation status is necessary to guide thrombolysis or reversal of anticoagulation in stroke patients, but commercially available point-of-care (POC) assays are not suited for coagu…
View article: Diagnosis of severe growth hormone deficiency in the newborn
Diagnosis of severe growth hormone deficiency in the newborn Open
Objective Severe neonatal growth hormone deficiency (GHD) can cause recurrent hypoglycaemia. Early diagnosis is warranted. The aim of the study was to analyse the GH content in screening cards of 25 affected and 281 healthy newborns. Patie…
View article: Epigenetic activation of O-linked β-N-acetylglucosamine transferase overrides the differentiation blockage in acute leukemia
Epigenetic activation of O-linked β-N-acetylglucosamine transferase overrides the differentiation blockage in acute leukemia Open
View article: Erratum zu: Langzeiterfahrungen des kornealen Crosslinkings bei Patienten mit progredientem Keratokonus an der Universitäts-Augenklinik Tübingen
Erratum zu: Langzeiterfahrungen des kornealen Crosslinkings bei Patienten mit progredientem Keratokonus an der Universitäts-Augenklinik Tübingen Open
View article: The Kids Obesity Prevention Program: Cluster Randomized Controlled Trial to Evaluate a Serious Game for the Prevention and Treatment of Childhood Obesity
The Kids Obesity Prevention Program: Cluster Randomized Controlled Trial to Evaluate a Serious Game for the Prevention and Treatment of Childhood Obesity Open
Background Health games provide opportunities for the treatment and prevention of childhood obesity. We developed a motion-controlled serious game for children that addresses 3 core topics of nutrition, physical activity, and stress coping…
View article: Treatment and outcome of the patients with rhabdomyosarcoma of the biliary tree: Experience of the Cooperative Weichteilsarkom Studiengruppe (CWS)
Treatment and outcome of the patients with rhabdomyosarcoma of the biliary tree: Experience of the Cooperative Weichteilsarkom Studiengruppe (CWS) Open
View article: Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study
Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study Open
Background We evaluated a magnetic resonance (MR)-conditional high-power microwave ablation system. Methods An ex vivo 1.5-T evaluation was conducted by varying the sequence (T1-weighted volume interpolated breath-hold examination, T1w-VIB…
View article: The Kids Obesity Prevention Program: Cluster Randomized Controlled Trial to Evaluate a Serious Game for the Prevention and Treatment of Childhood Obesity (Preprint)
The Kids Obesity Prevention Program: Cluster Randomized Controlled Trial to Evaluate a Serious Game for the Prevention and Treatment of Childhood Obesity (Preprint) Open
BACKGROUND Health games provide opportunities for the treatment and prevention of childhood obesity. We developed a motion-controlled serious game for children that addresses 3 core topics of nutrition, physical activity, and stress copin…
View article: Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes
Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes Open
BACKGROUND:This study investigated the effect of donor-dependent factors on contamination rates of conjunctival swabs of human donor eyes. MATERIAL AND METHODS:From July 2015 to September 2017 a total of 1008 conjunctival swabs from 504 co…