Svein Gunnar Gundersen
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View article: PREDICTORS FOR PARTICIPATION IN MASS-TREATMENT AND FEMALE GENITAL SCHISTOSOMIASIS RE-INVESTIGATION, AND THE EFFECT OF PRAZIQUANTEL TREATMENT IN SOUTH AFRICAN ADOLESCENTS
PREDICTORS FOR PARTICIPATION IN MASS-TREATMENT AND FEMALE GENITAL SCHISTOSOMIASIS RE-INVESTIGATION, AND THE EFFECT OF PRAZIQUANTEL TREATMENT IN SOUTH AFRICAN ADOLESCENTS Open
Objective Female Genital Schistosomiasis (FGS) causes intravaginal lesions and symptoms that could be mistaken for sexually transmitted diseases or cancer. In adults, FGS lesions are refractory to treatment. The effect of treatment has nev…
View article: Five-year results of a treatment program for chronic hepatitis B in Ethiopia
Five-year results of a treatment program for chronic hepatitis B in Ethiopia Open
Background In sub-Saharan Africa, less than 1% of treatment-eligible chronic hepatitis B (CHB) patients receive antiviral therapy. Experiences from local CHB programs are needed to inform treatment guidelines and policies on the continent.…
View article: Female Genital Schistosomiasis Lesions Explored Using Circulating Anodic Antigen as an Indicator for Live Schistosoma Worms
Female Genital Schistosomiasis Lesions Explored Using Circulating Anodic Antigen as an Indicator for Live Schistosoma Worms Open
Background In areas where reinfection with schistosomiasis is rampant, it is not known if the lesions of Female Genital Schistosomaisis are a consequence of live worms, or caused by dead ova. Live schistosome worms regurgitate Circulating …
View article: Co-infections and Comorbidities of Multiple Parasites and Hepatitis B Virus Infections in the Lowland Area of Western Ethiopia: Implications for Integrated Approaches
Co-infections and Comorbidities of Multiple Parasites and Hepatitis B Virus Infections in the Lowland Area of Western Ethiopia: Implications for Integrated Approaches Open
There was a high prevalence of infections in the study area. Morbidities such as undernutrition and anemia were still prominent public health problems. There was a significant association between infection status and undernutrition and ane…
View article: Current status of Schistosoma mansoni infection among previously treated rural communities in the Abbey and Didessa Valleys, Western Ethiopia: Implications for sustainable control
Current status of Schistosoma mansoni infection among previously treated rural communities in the Abbey and Didessa Valleys, Western Ethiopia: Implications for sustainable control Open
Background Schistosoma constitutes a major public health problem and developmental challenges in the majority of developing and subtropical regions. The World Health Organization has set guidelines for the control and elimination of schist…
View article: Additional file 4 of Low awareness and common misconceptions about schistosomiasis in endemic lowland areas in Western Ethiopia: a mixed-methods study
Additional file 4 of Low awareness and common misconceptions about schistosomiasis in endemic lowland areas in Western Ethiopia: a mixed-methods study Open
Additional file 4: Supplementary file 4 Data.xlsx
View article: Field performance of HBsAg rapid diagnostic tests in rural Ethiopia
Field performance of HBsAg rapid diagnostic tests in rural Ethiopia Open
Point-of-care rapid diagnostic tests (POC-RDTs) are widely used to screen and diagnose hepatitis B virus (HBV) infection and are often the only available diagnostic tools in resource-limited settings. The aim of this study was to evaluate …
View article: A systematic review of handheld tools in lieu of colposcopy for cervical neoplasia and female genital schistosomiasis
A systematic review of handheld tools in lieu of colposcopy for cervical neoplasia and female genital schistosomiasis Open
Background Visualization of the lesions in the lower genital tract is the mainstay for diagnosis of the four lesions found in female genital schistosomiasis (FGS), but colposcopes are generally not available in low‐resource settings. Objec…
View article: The cost of a school based mass treatment of schistosomiasis in Ugu District, KwaZulu Natal, South Africa in 2012
The cost of a school based mass treatment of schistosomiasis in Ugu District, KwaZulu Natal, South Africa in 2012 Open
Low coverage exacerbates the cost of the programme and makes a decision to support such a programme difficult. However, a normative costing study based on the integration of the programme within the Department of Health should be conducted.
View article: Prevalence and intensity of neglected tropical diseases (schistosomiasis and soil-transmitted helminths) amongst rural female pupils in Ugu district, KwaZulu-Natal, South Africa
Prevalence and intensity of neglected tropical diseases (schistosomiasis and soil-transmitted helminths) amongst rural female pupils in Ugu district, KwaZulu-Natal, South Africa Open
prevalence; intensity; schistosomiasis; soil-transmitted helminths; Ascaris lumbricoides; Trichuris trichiura; Schistosoma haematobium; parasite control programme; water contact.
View article: High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor?
High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor? Open
Background . Recent studies have identified chewing of khat ( Catha edulis ) as an independent risk factor for liver injury; however, the pathogenetic mechanism remains poorly understood. Case series have found markers of autoimmune hepati…
View article: Seasonal variations in Schistosoma haematobium egg excretion in school-age girls in rural KwaZulu-Natal Province, South Africa
Seasonal variations in Schistosoma haematobium egg excretion in school-age girls in rural KwaZulu-Natal Province, South Africa Open
Background. A predominant feature of Schistosoma haematobium infection is urinary egg excretion, and microscopic egg detection remains the accepted standard field diagnostic tool. Praziquantel is the drug of choice for schistosomiasis, and…
View article: Seasonal variations in Schistosoma haematobium egg excretion in school-age girls in rural KwaZulu-Natal Province, South Africa
Seasonal variations in Schistosoma haematobium egg excretion in school-age girls in rural KwaZulu-Natal Province, South Africa Open
This unique study shows that schistosomiasis prevalence determined by microscopy exhibits seasonal variation, with a higher prevalence in the hot rainy season. Precise community prevalence estimations are key in decisions to treat communit…
View article: Unexplained chronic liver disease in Ethiopia: a cross-sectional study
Unexplained chronic liver disease in Ethiopia: a cross-sectional study Open
The aetiology of CLD in eastern Ethiopia is largely unexplained. The widespread use of khat in the region, together with histopathological findings indicating toxic liver injury, suggests an association which warrants further investigation.
View article: Khat chewing increases the risk for developing chronic liver disease
Khat chewing increases the risk for developing chronic liver disease Open
A significant association was observed between chewing khat and the risk for developing CLD, and in men the association was strong and dose-dependent, suggesting a causal relationship; as the prevalence of khat chewing is increasing worldw…
View article: Environmental factors influencing the distribution and prevalence of<i>Schistosoma haematobium</i>in school attenders of ILembe and uThungulu Health Districts, KwaZulu-Natal Province, South Africa
Environmental factors influencing the distribution and prevalence of<i>Schistosoma haematobium</i>in school attenders of ILembe and uThungulu Health Districts, KwaZulu-Natal Province, South Africa Open
Schistosoma haematobium infection is reported to facilitate the development of urogenital diseases. Its symptoms include haematuria, dysuria and tiredness, and it may cause cognitive decline in children. The prevalence of S. haematobium in…
View article: Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa
Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa Open
NCT02344498 ( ClinicalTrials.gov identifier). Registered 16 January 2015.
View article: Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa
Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa Open
Schistosomiasis and soil-transmitted helminthiasis are among the most prevalent neglected tropical diseases and may lead to severe consequences. We assessed the extent of co-infection between Schistosoma haematobium and the soil-transmitte…
View article: Are non‐invasive fibrosis markers for chronic hepatitis B reliable in sub‐Saharan Africa?
Are non‐invasive fibrosis markers for chronic hepatitis B reliable in sub‐Saharan Africa? Open
Background In the absence of liver biopsy, the World Health Organization recommends non‐invasive tests, such as aspartate aminotransferase to platelet ratio index and FIB ‐4, to assess liver fibrosis in patients with chronic hepatitis B. H…
View article: NEW E-LEARNING TOOL FOR FEMALE GENITAL SCHISTOSOMIASIS: A SUPPLEMENT TO THE WHO POCKET ATLAS OF FGS
NEW E-LEARNING TOOL FOR FEMALE GENITAL SCHISTOSOMIASIS: A SUPPLEMENT TO THE WHO POCKET ATLAS OF FGS Open
Background Schistosomiasis affects 261 million people worldwide, most of them in Africa. Female genital schistosomiasis (FGS) may cause abnormal vaginal discharge, contact bleeding, genital tumours, infertility, ectopic pregnancies and inc…