Guohua Sun
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View article: Comprehensive Physiological and Transcriptomic Profiling of Triploid Pacific Oysters (Crassostrea gigas) Under Ammonia Exposure
Comprehensive Physiological and Transcriptomic Profiling of Triploid Pacific Oysters (Crassostrea gigas) Under Ammonia Exposure Open
Ammonia is a common toxic pollutant in aquaculture environments that poses significant threats to the health, growth, and survival of aquatic organisms. This study investigates the physiological and molecular responses of triploid Crassost…
View article: Three-dimensional digital design of orthopedic surgery for idiopathic scoliosis deformity: A case series
Three-dimensional digital design of orthopedic surgery for idiopathic scoliosis deformity: A case series Open
Objective To establish a new method of three-dimensional digital design for orthopedic surgery of idiopathic scoliosis deformity and evaluate its application value in surgical treatment. Methods The clinical data of 11 patients with idiopa…
View article: Effects of polypeptidin feeding on growth and intestinal flora of Apostichopus japonicus
Effects of polypeptidin feeding on growth and intestinal flora of Apostichopus japonicus Open
Apostichopus japonicus (A. japonicus) is known as one of the most popular varieties in aquaculture due to its rich nourishment and potential medicinal value. In recent years, with the abnormal change of marine environment and global climat…
View article: Exploration of Molecular Mechanisms of Immunity in the Pacific Oyster (Crassostrea gigas) in Response to Vibrio alginolyticus Invasion
Exploration of Molecular Mechanisms of Immunity in the Pacific Oyster (Crassostrea gigas) in Response to Vibrio alginolyticus Invasion Open
Over the years, oysters have faced recurring mass mortality issues during the summer breeding season, with Vibrio infection emerging as a significant contributing factor. Tubules of gill filaments were confirmed to be in the hematopoietic …
View article: Comparative Analysis of the Biochemical Composition, Amino Acid, and Fatty Acid Contents of Diploid, Triploid, and Tetraploid Crassostrea gigas
Comparative Analysis of the Biochemical Composition, Amino Acid, and Fatty Acid Contents of Diploid, Triploid, and Tetraploid Crassostrea gigas Open
Tetraploid oysters are artificially produced oysters that do not exist in nature. The successful breeding of 100% triploid oysters resolved the difficulties of traditional drug-induced triploids, such as the presence of drug residues and a…
View article: The investigation on stress mechanisms of Sepia esculenta larvae in the context of global warming and ocean acidification
The investigation on stress mechanisms of Sepia esculenta larvae in the context of global warming and ocean acidification Open
Sepia esculenta is a tasty and nutritious cephalopod. But the trend toward global warming is accelerating with massive emissions of greenhouse gases. An increase in seawater temperature and a decrease in pH are a great challenge for artifi…
View article: Transcriptome sequencing reveals the characteristics of spermatogenesis and testis development in Amphioctopus fangsiao
Transcriptome sequencing reveals the characteristics of spermatogenesis and testis development in Amphioctopus fangsiao Open
Spermatogenesis is the production of spermatozoa by the testes, a process that is associated with reproduction in males. Amphioctopus fangsiao is an economically important species from the northern coast of China, and little research has b…
View article: Exploring Endoplasmic Reticulum Stress Pathways in Apostichopus japonicus Under Heat Stress Based on Transcriptome Analysis
Exploring Endoplasmic Reticulum Stress Pathways in Apostichopus japonicus Under Heat Stress Based on Transcriptome Analysis Open
Background High summer temperatures caused by changes in the global environment have significant impacts on marine organisms. The sea cucumber Apostichopus japonicus is a representative marine benthic organism and an economically important…
View article: Weighted Gene Co-Expression Network Analysis Based on Stimulation by Lipopolysaccharides and Polyinosinic:polycytidylic Acid Provides a Core Set of Genes for Understanding Hemolymph Immune Response Mechanisms of Amphioctopus fangsiao
Weighted Gene Co-Expression Network Analysis Based on Stimulation by Lipopolysaccharides and Polyinosinic:polycytidylic Acid Provides a Core Set of Genes for Understanding Hemolymph Immune Response Mechanisms of Amphioctopus fangsiao Open
The primary influencer of aquaculture quality in Amphioctopus fangsiao is pathogen infection. Both lipopolysaccharides (LPS) and polyinosinic:polycytidylic acid (Poly I:C) are recognized by the pattern recognition receptor (PRR) within imm…
View article: Investigating the molecular mechanism of sterility in female triploid Pacific oyster (Crassostrea gigas)
Investigating the molecular mechanism of sterility in female triploid Pacific oyster (Crassostrea gigas) Open
The emergence of triploid oysters has freed the oyster market from the problem of interruptions in the breeding season, allowing for year-round availability. However, according to recent statistics, the phenomenon of fertility in triploid …
View article: Comparative analysis of biochemical composition, amino acids, and fatty acids among diploid, triploid, and tetraploid Crassostrea gigas
Comparative analysis of biochemical composition, amino acids, and fatty acids among diploid, triploid, and tetraploid Crassostrea gigas Open
Tetraploid oysters are artificially produced oysters that do not exist in nature. The successful breeding of 100% triploid oysters resolved the difficulties with traditional drug–induced triploids such as the presence of drug residues and …
View article: Investigating the Mechanism of Low-Salinity Environmental Adaptation in Sepia esculenta Larvae through Transcriptome Profiling
Investigating the Mechanism of Low-Salinity Environmental Adaptation in Sepia esculenta Larvae through Transcriptome Profiling Open
Sepia esculenta is an economically important mollusk distributed in the coastal waters of China. Juveniles are more susceptible to stimulation by the external environment than mature individuals. The ocean salinity fluctuates due to enviro…
View article: Sequencing-based protein–protein interaction analysis provides an immune gene network for understanding white body immune response mechanisms against Poly I:C stimulation in Amphioctopus fangsiao
Sequencing-based protein–protein interaction analysis provides an immune gene network for understanding white body immune response mechanisms against Poly I:C stimulation in Amphioctopus fangsiao Open
Pathogen threats pose a significant limitation in the culture of marine organisms like cephalopods. Yet, there is a notable lack of immune information regarding cephalopods. Polyriboinosinic polyribocytidylic acid (Poly I:C), a synthetic v…
View article: Genome-wide analysis of DNA methylation reveals significant impact of two typical high temperature stress on biological functions in Apostichopus japonicus
Genome-wide analysis of DNA methylation reveals significant impact of two typical high temperature stress on biological functions in Apostichopus japonicus Open
Sea cucumber Apostichopus japonicus, an important marine benthic animal, is particularly sensitive to environmental temperature stress, which affected the growth, metabolism, and reproduction even survival. In this study, we used whole gen…
View article: The morphological characteristics and modification of the oviducal glands adapted for long-term sperm storage and fertilization in Amphioctopus fangsiao
The morphological characteristics and modification of the oviducal glands adapted for long-term sperm storage and fertilization in Amphioctopus fangsiao Open
Sperm storage is an important reproductive strategy in Amphioctopus fangsiao. Sperm can be stored in the oviducal glands up to eight months before fertilization. However, studies on the underlying storage mechanisms remain limited. In this…
View article: Exploration of immune response mechanisms in cadmium and copper co-exposed juvenile golden cuttlefish (Sepia esculenta) based on transcriptome profiling
Exploration of immune response mechanisms in cadmium and copper co-exposed juvenile golden cuttlefish (Sepia esculenta) based on transcriptome profiling Open
Sepia esculenta is a popular economic cephalopod with high yield, delicious meat, and rich nutrition. With the rapid development of heavy industry and medical industry, a large amount of waste has been released into the ocean recklessly in…
View article: Transcriptome Profiling Based on Larvae at Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding the Metabolic Mechanisms of the Brood-Care Behavior in Octopus ocellatus
Transcriptome Profiling Based on Larvae at Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding the Metabolic Mechanisms of the Brood-Care Behavior in Octopus ocellatus Open
The metabolic processes of organisms are very complex. Each process is crucial and affects the growth, development, and reproduction of organisms. Metabolism-related mechanisms in Octopus ocellatus behaviors have not been widely studied. B…
View article: Comprehensive Analysis of Differentially Expressed mRNA, Non-coding RNA, and Their Competitive Endogenous RNA Network of Pacific Oyster Crassostrea gigas With Different Glycogen Content Between Different Environments
Comprehensive Analysis of Differentially Expressed mRNA, Non-coding RNA, and Their Competitive Endogenous RNA Network of Pacific Oyster Crassostrea gigas With Different Glycogen Content Between Different Environments Open
Glycogen content is a quantitative trait, its phenotype differences are found between individual oysters due to genetic effects and environmental factors which were including food, water temperature, salinity, and so on. In this study, a f…
View article: Transcriptome Profiling Based on Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding Larval Immune Response Mechanisms Against Vibrio anguillarum Infection in Amphioctopus fangsiao
Transcriptome Profiling Based on Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding Larval Immune Response Mechanisms Against Vibrio anguillarum Infection in Amphioctopus fangsiao Open
Immune defense systems are indispensable for living organisms. Within an immune network, problems with any given link can impact the normal life activities of an organism. Amphioctopus fangsiao is a cephalopod that exists widely throughout…
View article: A Ten-year Experience of the Multidisciplinary Management of the Regional Failure of Nasopharyngeal Carcinoma in the Era of IMRT
A Ten-year Experience of the Multidisciplinary Management of the Regional Failure of Nasopharyngeal Carcinoma in the Era of IMRT Open
Objective: To evaluate clinical outcomes of cervical node recurrence/residual tumor of nasopharyngeal carcinoma (NPC) with treatment decisions made by a multidisciplinary treatment (MDT) team. Methods: Between March 2010 and July 2019, pat…
View article: Human papillomavirus (HPV) in Chinese oropharyngeal squamous cell carcinoma (OPSCC): A strong predilection for the tonsil
Human papillomavirus (HPV) in Chinese oropharyngeal squamous cell carcinoma (OPSCC): A strong predilection for the tonsil Open
Objective Compared with Occident's data, the incidence of Human papillomavirus (HPV)‐driven oropharyngeal squamous cell carcinomas (OPSCCs) had been reported as relatively low in Mainland China. The objective of this study was to report th…
View article: The Application of Hemithyroidectomy Plus Central Neck Dissection in the Initial Surgical Treatment of Papillary Thyroid Microcarcinoma
The Application of Hemithyroidectomy Plus Central Neck Dissection in the Initial Surgical Treatment of Papillary Thyroid Microcarcinoma Open
Introduction: Hemithyroidectomy plus central lymph node dissection (CLND) currently is applied commonly as the initial surgical management of patients with papillary thyroid microcarcinoma (PTMC), with or without overt lymph nodes clinical…