Guojun Wang
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View article: Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy
Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy Open
Immunotherapy has rapidly emerged as a transformative advancement in cancer treatment, becoming essential for managing diverse malignancies. Despite the remarkable clinical efficacy of immunotherapies, including immune checkpoint inhibitor…
View article: Exploring potential mechanistic aspects of “Biaoben acupoint” acupuncture for lumbar disc herniation using 4D proteomics
Exploring potential mechanistic aspects of “Biaoben acupoint” acupuncture for lumbar disc herniation using 4D proteomics Open
Objective To investigate the mechanism of action of “Biaoben acupoint” acupuncture in treating lumbar disc herniation (LDH) by identifying differentially expressed plasma proteins (DEPs) using timsTOF Pro-based 4D data-independent acquisit…
View article: Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infection
Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infection Open
Reassortment between different influenza strains occurs when they co-infect the same host cell. The emergence of a reassortant virus depends on both its intrinsic fitness and extrinsic factors, including pre-existing humoral immunity. The …
View article: Optimization of inductor current stress in DAB converter based on improved particle swarm optimization
Optimization of inductor current stress in DAB converter based on improved particle swarm optimization Open
The DAB converter has been widely employed in the industrial sector due to its characteristic of a wide range of input voltages. Nevertheless, the realization of ZVS and the optimization of inductor current under a broad input voltage rang…
View article: Pathological Characteristics of Pregnant Tree Shrews Infected by Zoonotic Hepatitis E Virus Genotype and the Effect of Estrogen on Virus Replication
Pathological Characteristics of Pregnant Tree Shrews Infected by Zoonotic Hepatitis E Virus Genotype and the Effect of Estrogen on Virus Replication Open
Hepatitis E, caused by the hepatitis E virus (HEV), is a zoonotic disease that extends beyond hepatocellular necrosis to replicate in multiple organs. While most infections are self-limiting, HEV infection during pregnancy is associated wi…
View article: Ionospheric response forecasting and analysis during magnetic storm by a short-term ionogram prediction model
Ionospheric response forecasting and analysis during magnetic storm by a short-term ionogram prediction model Open
During magnetic storm, the ionpsheric plasma vertical distribution would show some variations such as in foF2, h'F, hmF2, et al., and the disturbances may deveop into irregularities as Spread-F in ionogram.We have made a high-definition pr…
View article: Comparative study of additive manufacturing thin-walled component with Al–Mg-Sc-Zr alloy using different arc modes
Comparative study of additive manufacturing thin-walled component with Al–Mg-Sc-Zr alloy using different arc modes Open
Four types of Al–Mg-Sc-Zr deposited metal were produced by wire arc additive manufacturing(WAAM) with conventional CMT(cold metal transfer), CMT + P(CMT pulse), CMT + ADV(CMT advanced) and CMT + PADV(CMT pulse advanced) arc modes, respecti…
View article: The Impact of Different Excavation Support Structures on the Deformation and Stability of Adjacent Station and Tunnels
The Impact of Different Excavation Support Structures on the Deformation and Stability of Adjacent Station and Tunnels Open
This study uses the finite element software Midas GTS NX (2019), combined with actual engineering projects, to establish numerical models and analyze the impact of different support types (pile-anchor support and double-row pile support) o…
View article: Comparative clinical efficacy of acupuncture combined with manipulation and other non-pharmacological interventions in the treatment of lumbar disc herniation: a prospective, multi-arm, randomized, open-label, blinded endpoint trial
Comparative clinical efficacy of acupuncture combined with manipulation and other non-pharmacological interventions in the treatment of lumbar disc herniation: a prospective, multi-arm, randomized, open-label, blinded endpoint trial Open
Objective To compare the clinical efficacy and safety of four intervention methods—traditional Chinese manipulation combined with acupuncture, acupuncture alone, manipulation alone, and traction—for the treatment of lumbar disc herniation …
View article: Progress of material degradation: metals and polymers in deep-sea environments
Progress of material degradation: metals and polymers in deep-sea environments Open
Given the critical need for ocean exploration, improving the durability of materials in the deep-sea has become a paramount concern. The harshness of deep-sea, such as high pressure, variable seawater flow rates, and corrosive media, lead …
View article: Backdoor Attacks and Defenses Targeting Multi-Domain AI Models: A Comprehensive Review
Backdoor Attacks and Defenses Targeting Multi-Domain AI Models: A Comprehensive Review Open
Since the emergence of security concerns in artificial intelligence (AI), there has been significant attention devoted to the examination of backdoor attacks. Attackers can utilize backdoor attacks to manipulate model predictions, leading …
View article: A survey on textual emotion cause extraction in social networks
A survey on textual emotion cause extraction in social networks Open
With the rapid development of web technology, Social Networks (SNs) have become one of the most popular platforms for users to exchange views and to express their emotions. More and more people are used to commenting on a certain hot spot …
View article: Microstructure Dependence of Magnetic Properties for Al1.5Fe3Co3Cr1 Multi-Principal-Element Alloy
Microstructure Dependence of Magnetic Properties for Al1.5Fe3Co3Cr1 Multi-Principal-Element Alloy Open
This study focuses on the microstructures and soft-magnetic properties of the Al1.5Fe3Co3Cr1 multi-principal-element alloy (MPEA) in different states. The MPEA was prepared using arc melting and suction-casting, followed by various heat tr…
View article: Numerical Simulation of Extreme Ice Loads on Complex Pile Legs of Offshore Substation Structures
Numerical Simulation of Extreme Ice Loads on Complex Pile Legs of Offshore Substation Structures Open
The sea ice failure mode and ice force amplitude depend on the structural form at the point of interaction, but the impacts of ice load when interacting with marine engineering structures with additional attachments are not yet clear. This…
View article: Structural Optimization and Control System Design for a Rake Dryer
Structural Optimization and Control System Design for a Rake Dryer Open
Optimization of process parameters and process intelligent control of the production process is an important part of the design and development of drying equipment. This research proposed a new type of jacket and conical screw belt composi…
View article: Detecting unknown vulnerabilities in smart contracts using opcode sequences
Detecting unknown vulnerabilities in smart contracts using opcode sequences Open
Unknown vulnerabilities, also known as zero-day vulnerabilities, are vulnerabilities in software, systems, or networks that have not yet been publicly disclosed or fixed. If these vulnerabilities are ever discovered by hackers, intentional…
View article: Effect of different wire composition on microstructure and properties of welded joint of 6XXX extruded alloys
Effect of different wire composition on microstructure and properties of welded joint of 6XXX extruded alloys Open
Er/Zr and Sc/Zr were added into 5xxx series alloy to prepare welding wires, and the welding wires with the different compositions were used to weld 6xxx extruded alloy. The effects of different alloying additions on the microstructure and …
View article: Chaotic Map-Based Authentication and Key Agreement Protocol with Low-Latency for Metasystem
Chaotic Map-Based Authentication and Key Agreement Protocol with Low-Latency for Metasystem Open
With the rapid advancement in exploring perceptual interactions and digital twins, metaverse technology has emerged to transcend the constraints of space-time and reality, facilitating remote AI-based collaboration. In this dynamic metasys…
View article: Toward Answering Federated Spatial Range Queries Under Local Differential Privacy
Toward Answering Federated Spatial Range Queries Under Local Differential Privacy Open
Federated analytics (FA) over spatial data with local differential privacy (LDP) has attracted considerable research attention recently. Existing solutions for this problem mostly employ a uniform grid (UG) structure, which recursively dec…
View article: FRAD: Front-Running Attacks Detection on Ethereum using Ternary Classification Model
FRAD: Front-Running Attacks Detection on Ethereum using Ternary Classification Model Open
With the evolution of blockchain technology, the issue of transaction security, particularly on platforms like Ethereum, has become increasingly critical. Front-running attacks, a unique form of security threat, pose significant challenges…
View article: Molecular characteristics of VP4 and VP7 of a Rotavirus A in cattle in Yunnan Province, China
Molecular characteristics of VP4 and VP7 of a Rotavirus A in cattle in Yunnan Province, China Open
Rotavirus is classified within the family Reoviridae, subfamily Sedoreovirinae, and the genus Rotavirus. This genus encompasses eight groups, denoted as species A to H, with Group A holding particular significance due to its widespread pre…
View article: Research on the Performance Characteristics and Unsteady Flow Mechanism of a Centrifugal Pump under Pitch Motion
Research on the Performance Characteristics and Unsteady Flow Mechanism of a Centrifugal Pump under Pitch Motion Open
Pitch motion is the key factor affecting the performance characteristics of centrifugal pumps on board ships and exacerbates hydraulic excitation to induce the unsteady vibration of pump units. A hydraulic test platform with swing motion i…