Ye Guo
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Author Swipe
View article: Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)
Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review) Open
View article: Central nervous system involvement-positive disease in consolidation/maintenance stage is a poor prognostic factor in pediatric T-cell acute lymphoblastic leukemia: a Chinese single-center report
Central nervous system involvement-positive disease in consolidation/maintenance stage is a poor prognostic factor in pediatric T-cell acute lymphoblastic leukemia: a Chinese single-center report Open
Background The incidence of central nervous system (CNS) leukemia is approximately 5%-10% in pediatric T-cell acute lymphoblastic leukemia (T-ALL), typically conferring a poor prognosis. Materials and Methods We further investigated the re…
View article: Relapse risk and outcome of discontinuing asparaginase in children with acute lymphoblastic leukemia
Relapse risk and outcome of discontinuing asparaginase in children with acute lymphoblastic leukemia Open
Asparaginase is a cornerstone of pediatric acute lymphoblastic leukemia (ALL) therapy, but treatment discontinuation due to toxicity may increase relapse risk and compromise outcomes. We retrospectively analyzed 993 pediatric ALL patients …
View article: Diagnostic value of pathogen metagenomic next-generation sequencing (mNGS) for early bloodstream infections in pediatric allogeneic hematopoietic stem cell transplantation recipients
Diagnostic value of pathogen metagenomic next-generation sequencing (mNGS) for early bloodstream infections in pediatric allogeneic hematopoietic stem cell transplantation recipients Open
Background: Early bloodstream infection (EBSI) remains a principal determinant of morbidity and mortality after paediatric allogeneic haematopoietic stem-cell transplantation (allo-HSCT). Metagenomic next-generation sequencing (mNGS) offer…
View article: Mini-ATG/TBI conditioning regimen facilitates cure of acquired aplastic anemia in children via unrelated umbilical cord blood transplantation
Mini-ATG/TBI conditioning regimen facilitates cure of acquired aplastic anemia in children via unrelated umbilical cord blood transplantation Open
Introduction: Umbilical cord blood transplantation (UCBT) represents a alternative therapeutic option for patients with acquired aplastic anemia (AA) lacking a HLA-matched sibling donor. However, high incidences of graft failure and acute …
View article: Cembrane-Based Diterpenoids Isolated from the Soft Coral Sarcophyton sp.
Cembrane-Based Diterpenoids Isolated from the Soft Coral Sarcophyton sp. Open
This research explored the chemical composition of the soft coral Sarcophyton sp., leading to the discovery of six previously unreported cembranoids, sarcophynoids D–I (1–6), and three known analog compounds (7–9). Structural elucidation o…
View article: D3-Talker: Dual-Branch Decoupled Deformation Fields for Few-Shot 3D Talking Head Synthesis
D3-Talker: Dual-Branch Decoupled Deformation Fields for Few-Shot 3D Talking Head Synthesis Open
A key challenge in 3D talking head synthesis lies in the reliance on a long-duration talking head video to train a new model for each target identity from scratch. Recent methods have attempted to address this issue by extracting general f…
View article: Developing and validating a nomogram for predicting endoscopic hemostasis failure in cirrhotic patients with esophageal variceal bleeding
Developing and validating a nomogram for predicting endoscopic hemostasis failure in cirrhotic patients with esophageal variceal bleeding Open
Background and aims This study aimed to create and validate a model to predict the failure of endoscopic hemostasis in Chinese cirrhosis patients with acute esophagogastric variceal bleeding (EGVB), enabling early identification of high-ri…
View article: Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer
Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer Open
BACKGROUND Non-small cell lung cancer (NSCLC) is the most prevalent subtype of lung cancer, accounting for approximately 85% of all lung cancer cases and remaining a major cause of cancer-related mortality worldwide. Despite advances in di…
View article: Editorial: Head and neck squamous cell carcinoma: navigating the dawn of personalized medicine
Editorial: Head and neck squamous cell carcinoma: navigating the dawn of personalized medicine Open
View article: MAGdb: a comprehensive high quality MAGs repository for exploring microbial metagenome-assemble genomes
MAGdb: a comprehensive high quality MAGs repository for exploring microbial metagenome-assemble genomes Open
Metagenomic analyses of microbial communities have unveiled a substantial level of interspecies and intraspecies genetic diversity by reconstructing metagenome-assembled genomes (MAGs). The MAG database (MAGdb) boasts an impressive collect…
View article: 1494P Pooled efficacy and safety outcomes with tremelimumab plus durvalumab in participants (pts) with unresectable hepatocellular carcinoma (uHCC) from the combined China extension and global cohorts in the phase III HIMALAYA study
1494P Pooled efficacy and safety outcomes with tremelimumab plus durvalumab in participants (pts) with unresectable hepatocellular carcinoma (uHCC) from the combined China extension and global cohorts in the phase III HIMALAYA study Open
View article: Experiences of Patients with Heart Failure in Transition from Hospital to Home in China: A Qualitative Study
Experiences of Patients with Heart Failure in Transition from Hospital to Home in China: A Qualitative Study Open
The study concludes that there is an urgent need for transitional care reform in China, including standardised discharge protocols, hospital-led telehealth platforms and government-subsidised rehabilitation programmes. These interventions …
View article: LBA48 BURAN: A phase III study of buparlisib (BUP) plus paclitaxel (PAC) in patients with PD-1(PD-L1)-pretreated recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC)
LBA48 BURAN: A phase III study of buparlisib (BUP) plus paclitaxel (PAC) in patients with PD-1(PD-L1)-pretreated recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) Open
View article: Coexistence of human pegivirus infection and poor hematopoietic reconstruction in a lymphoma patient after autologous hematopoietic stem cell transplantation: A case report and literature review
Coexistence of human pegivirus infection and poor hematopoietic reconstruction in a lymphoma patient after autologous hematopoietic stem cell transplantation: A case report and literature review Open
Rationale: Lymphoblastic lymphoma (LBL) is an exceptionally aggressive form of lymphoma. Following the achievement of complete remission through induction therapy, it is imperative to proceed with consolidation and intensive treatment, sub…
View article: D^3-Talker: Dual-Branch Decoupled Deformation Fields for Few-Shot 3D Talking Head Synthesis
D^3-Talker: Dual-Branch Decoupled Deformation Fields for Few-Shot 3D Talking Head Synthesis Open
A key challenge in 3D talking head synthesis lies in the reliance on a long-duration talking head video to train a new model for each target identity from scratch. Recent methods have attempted to address this issue by extracting general f…
View article: Exploring health challenges and coping strategies in young patients undergoing maintenance hemodialysis: a qualitative study
Exploring health challenges and coping strategies in young patients undergoing maintenance hemodialysis: a qualitative study Open
View article: What drives hyperammonemic encephalopathy in AED users: monotherapy risks or polypharmacy perils?
What drives hyperammonemic encephalopathy in AED users: monotherapy risks or polypharmacy perils? Open
Background and objectives Hyperammonemic encephalopathy (HE) is a serious side effect linked to sodium valproate (VPA). Recent case studies indicate that newer antiepileptic drugs (AEDs) might also trigger HE, whether used alone or alongsi…
View article: ABS0261 ALTERED TRYPTOPHAN PATHWAY METABOLISM AND ASSOCIATION WITH RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE IN ANTI-MDA5 POSITIVE DERMATOMYOSITIS
ABS0261 ALTERED TRYPTOPHAN PATHWAY METABOLISM AND ASSOCIATION WITH RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE IN ANTI-MDA5 POSITIVE DERMATOMYOSITIS Open
View article: 439 | ANALYSIS OF A PHASE 1 STUDY OF ZANUBRUTINIB + LENALIDOMIDE IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA
439 | ANALYSIS OF A PHASE 1 STUDY OF ZANUBRUTINIB + LENALIDOMIDE IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA Open
View article: [Genetic and clinical characteristics of children with <i>RAS</i>-mutated juvenile myelomonocytic leukemia].
[Genetic and clinical characteristics of children with <i>RAS</i>-mutated juvenile myelomonocytic leukemia]. Open
Children with NRAS compound mutations have a later onset age compared to those with isolated NRAS mutations. At initial diagnosis, children with NRAS compound mutations have poorer peripheral platelet and fetal hemoglo…
View article: Management approaches for recurrent or metastatic head and neck squamous cell carcinoma after anti-PD-1/PD-L1 immunotherapy
Management approaches for recurrent or metastatic head and neck squamous cell carcinoma after anti-PD-1/PD-L1 immunotherapy Open
Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer globally. For patients with recurrent or metastatic (R/M) HNSCC, immunotherapy represents an important advance in clinical practice as an effective and widely …
View article: Long-term outcome of using Ara-C or not in children’s APL
Long-term outcome of using Ara-C or not in children’s APL Open
The use of cytarabine (Ara-C) in treating acute promyelocytic leukemia (APL) is controversial. This study was conducted to demonstrate the effect of treatment with or without Ara-C on long-term event-free survival (EFS) or overall survival…
View article: Plasma Lipidomics Profiling of Developmental Dysplasia of the Hip in Tibet Plateau
Plasma Lipidomics Profiling of Developmental Dysplasia of the Hip in Tibet Plateau Open
Background Developmental dysplasia of the hip (DDH) is a prevalent pediatric condition with a multifactorial etiology. Its incidence varies geographically, with notably higher rates observed on the Tibet plateau. This study was performed t…
View article: Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection (Adv. Sci. 15/2025)
Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection (Adv. Sci. 15/2025) Open
Accurate Gastric Cancer Detection In this study a bimodal EV‐circRNA analyzer (BEISA) for detecting circular RNA in gastric cancerderived extracellular vesicles (EVs) is developed. BEISA employs RF‐HCR to generate dual fluorescent and elec…
View article: <i>TP53</i> deletion as an MRD‐dependent risk factor in childhood B‐ALL: A post hoc analysis from a prospective cohort
<i>TP53</i> deletion as an MRD‐dependent risk factor in childhood B‐ALL: A post hoc analysis from a prospective cohort Open
The effect of TP53 alterations on childhood B‐cell acute lymphoblastic leukemia (B‐ALL) remains unclear. To investigate the prognostic value of TP53 deletion ( TP53 del ) and TP53 mutation ( TP53 mut ), this post hoc study used fluorescenc…
View article: Treatment decision-making factors and sequencing in recurrent and/or metastatic squamous cell carcinoma of the head and neck
Treatment decision-making factors and sequencing in recurrent and/or metastatic squamous cell carcinoma of the head and neck Open
Treatment options for patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) have evolved over the past decade and have helped improve survival outcomes for patients. Most national and regional g…
View article: A pilot study of endobronchial repairment for bronchopleural fistulas
A pilot study of endobronchial repairment for bronchopleural fistulas Open
Four endobronchial interventional maneuvers, the Vaseline gauze, shape-adjustable silicone plug, sutured silicone tube and covered metallic stent, showed both safe and effective managements for patients with BPFs.
View article: Prevalence and morphology of middle mesial canals in mandibular first molars and their relationship with anatomical aspects of the mesial root: a CBCT analysis
Prevalence and morphology of middle mesial canals in mandibular first molars and their relationship with anatomical aspects of the mesial root: a CBCT analysis Open
The morphology of MMCs is complex, and most of them exhibit confluent canals. In instances where MMCs are present, the MB-ML distance is significantly larger. For effective detection of MMC, a thorough examination of the area within 4 mm b…
View article: Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection
Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection Open
Circular RNAs in extracellular vesicles (EV‐circRNAs) are gaining recognition as potential biomarkers for the diagnosis of gastric cancer (GC). Most current research is focused on identifying new biomarkers and their functional significanc…