Guobing Wang
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View article: Letter to the editor comments on ʻPBK as a Novel Biomarker with Excellent Diagnostic and Prognostic Value in HCC Associated with Immune Infiltration and Methylationʼ
Letter to the editor comments on ʻPBK as a Novel Biomarker with Excellent Diagnostic and Prognostic Value in HCC Associated with Immune Infiltration and Methylationʼ Open
This manuscript presents a letter to the editor addressing the study by Lv et al. (J Mol Histol 56(2):129, 2025), which identifies PDZ-binding kinase (PBK) as a diagnostic and prognostic biomarker for hepatocellular carcinoma (HCC). While …
View article: Letter to the editor: “high variability in the assessment of physical function following total hip arthroplasty: a systematic review”
Letter to the editor: “high variability in the assessment of physical function following total hip arthroplasty: a systematic review” Open
View article: Analysis of the Coupling Laws between Thermal Insulation Performance and Mechanical Properties of a New Vitrified Microbead (VMB) Smart Insulation Mortar for Reinforcing Existing Masonry Structures
Analysis of the Coupling Laws between Thermal Insulation Performance and Mechanical Properties of a New Vitrified Microbead (VMB) Smart Insulation Mortar for Reinforcing Existing Masonry Structures Open
In masonry structure reinforcement projects, exterior wall reinforcement with steel mesh and insulation layer construction are typically carried out independently. Mixing insulation materials into mortar achieves both thermal insulation an…
View article: Letter to the editor regarding the article ʻEvaluating the impact of radical prostatectomy and pathological upgrading on prognosis in non-clinically significant prostate cancerʼ
Letter to the editor regarding the article ʻEvaluating the impact of radical prostatectomy and pathological upgrading on prognosis in non-clinically significant prostate cancerʼ Open
View article: Predictive modeling analysis of the degree and scope of damage impacts on villagers' self-built houses due to uneven unsaturated soil site vibrations induced by self-dropping heavy hammer percussive hole formation construction
Predictive modeling analysis of the degree and scope of damage impacts on villagers' self-built houses due to uneven unsaturated soil site vibrations induced by self-dropping heavy hammer percussive hole formation construction Open
View article: Potential Influence of Different Stress Release Rates on Lining Cracking in Tunnel Engineering
Potential Influence of Different Stress Release Rates on Lining Cracking in Tunnel Engineering Open
The core problem of tunnel stability in the process of tunnel excavation lies in the controllable degree of stress release of the surrounding rock stratum, and stress release rate not only affects the judgment of the tunnel support timing,…
View article: Scutellaria Barbata inhibits epithelial-mesenchymal transformation through PI3K/AKT and MDM2 thus inhibiting the proliferation, migration and promoting apoptosis of Cervical Cancer cells
Scutellaria Barbata inhibits epithelial-mesenchymal transformation through PI3K/AKT and MDM2 thus inhibiting the proliferation, migration and promoting apoptosis of Cervical Cancer cells Open
Background Cervical cancer is the fourth most common malignant tumor among women with high morbidity and mortality. We found the active ingredients, action targets and pathways of Scutellaria Barbata against cervical cancer cells, and veri…
View article: Elevated ACP2 expression indicates unfavorable outcomes in gliomas
Elevated ACP2 expression indicates unfavorable outcomes in gliomas Open
View article: Exploring novel biomarkers and immunotherapeutic targets for biofeedback therapies to reveal the tumor-associated immune microenvironment through a multimetric analysis of kidney renal clear cell carcinoma
Exploring novel biomarkers and immunotherapeutic targets for biofeedback therapies to reveal the tumor-associated immune microenvironment through a multimetric analysis of kidney renal clear cell carcinoma Open
This study presents an innovative prognostic framework for KIRC based on multi-omics approaches, seamlessly incorporating CRs. This model holds promise for improving the accuracy of prognosis prediction for KIRC patients, laying a robust f…
View article: Anecic Earthworms and Residue Management Synergistically Enhance Soil Carbon Sequestration via Macroaggregate Formation
Anecic Earthworms and Residue Management Synergistically Enhance Soil Carbon Sequestration via Macroaggregate Formation Open
View article: Analysis of the Effect of Nonlocal Factors on the Vibration of Euler-Bernoulli Beams
Analysis of the Effect of Nonlocal Factors on the Vibration of Euler-Bernoulli Beams Open
Currently, the Euler-Bernoulli beam theory relies mainly on the classical continuous medium and local elasticity theories in vibration analysis, but fails to take into account the length interactions between atomic lattices, which makes it…
View article: Presumptive Study of Temperature and Residual Strength of Desulfurization Tower Structure During and after Fire
Presumptive Study of Temperature and Residual Strength of Desulfurization Tower Structure During and after Fire Open
Currently, the presumption of temperature and residual strength of structural components of desulfurization tower during and after fire has become one of the key difficulties in the analysis of structural safety of desulfurization tower. T…
View article: Forest Development Determines the Compositions and Structures of Soil Invertebrate Communities in Reclaimed Coastal Lands
Forest Development Determines the Compositions and Structures of Soil Invertebrate Communities in Reclaimed Coastal Lands Open
Soil fauna is integral to facilitating material cycles, energy flows, and the conservation of biodiversity in terrestrial ecosystems. However, the impacts of forest development on the compositions and structures of soil invertebrates remai…
View article: Forest Development Alters the Compositions and Structures of Soil Macrofauna Communities in Reclaimed Coastal Lands
Forest Development Alters the Compositions and Structures of Soil Macrofauna Communities in Reclaimed Coastal Lands Open
Soil fauna is integral to facilitating material cycles, energy flows, and the conservation of biodiversity in terrestrial ecosystems. However, the impacts of forest development on the compositions and structures of surface soil macrofauna …
View article: Analysis of a Steel Frame Structure in Loess Area for Correcting Deflection and Stopping Tilting Reinforcement
Analysis of a Steel Frame Structure in Loess Area for Correcting Deflection and Stopping Tilting Reinforcement Open
Currently, Surface water infiltration saturates the soil layer of the building foundation, is causing uneven settlement of the pile foundation of the building, resulting in obvious tilting and deformation of the upper main structure. The p…
View article: Analysis of Maintenance Methods and Process Improvement of Vacuum Laser Collimation System for Dams
Analysis of Maintenance Methods and Process Improvement of Vacuum Laser Collimation System for Dams Open
The method and process of vacuum laser collimation system maintenance is one of the key technologies directly related to the accuracy of dam vacuum laser collimation system measurement value. Taking the maintenance methods and processes of…
View article: Nano-indentation study of dislocation evolution in GaN-based laser diodes
Nano-indentation study of dislocation evolution in GaN-based laser diodes Open
The slip systems and motion behavior of dislocations induced by nano-indentation technique in GaN-based LDs were investigated. Dislocations with burgers vector of b = 1/3 3> were introduced on either {11 $$\overline{2}$$ 2} 3>, or …
View article: Differences in Fine Root Foraging Traits of Two Dominant Tree Species (Cunninghamia lanceolata and Quercus acutissima) in Subtropical Forests
Differences in Fine Root Foraging Traits of Two Dominant Tree Species (Cunninghamia lanceolata and Quercus acutissima) in Subtropical Forests Open
Root biomass and length growth, functional traits, and their responses to soil nutrient availability are crucial for resource acquisition under environmental change. Previous studies have focused on the response of root morphological, arch…
View article: XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis
XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis Open
X-ray repair cross-complementation group 1 (XRCC1) is a pivotal contributor to base excision repair, and its dysregulation has been implicated in the oncogenicity of various human malignancies. However, a comprehensive pan-cancer analysis …
View article: Utility of four machine learning approaches for identifying ulcerative colitis and Crohn's disease
Utility of four machine learning approaches for identifying ulcerative colitis and Crohn's disease Open
PBRPs-based MLP-ANN model exhibited good performance in discriminating between UC and CD and revealing the disease activity; however, a larger sample size and more models need to be considered for further research.
View article: Nano-indentation study of dislocation evolution in GaN-based Laser Diodes
Nano-indentation study of dislocation evolution in GaN-based Laser Diodes Open
The slip systems and motion behavior of dislocations induced by nano-indentation technique in GaN-based LDs were investigated. Dislocations with burgers vector of b = 1/3 < 11\(\stackrel{-}{2}\)3> were introduced on either {11\(\stackrel{-…
View article: Unravelling the complexity of kidney renal clear cell carcinoma prognosis: integrating chromatin regulators, gene signatures and associated immune landscapes
Unravelling the complexity of kidney renal clear cell carcinoma prognosis: integrating chromatin regulators, gene signatures and associated immune landscapes Open
Background Kidney-renal clear cell carcinoma (KIRC) is the main subtype of renal cell carcinoma. KIRC exhibits significant resistance to conventional treatments, highlighting the need for pioneering therapeutic approaches. Within this fram…
View article: The Application Effect of Craniotomy through Transsylvian Rolandic Point-Insular Approach on Hypertensive Intracerebral Hemorrhage in Posterior Basal Ganglia
The Application Effect of Craniotomy through Transsylvian Rolandic Point-Insular Approach on Hypertensive Intracerebral Hemorrhage in Posterior Basal Ganglia Open
Objective. To evaluate the hematoma clearance and safety of small bone window craniotomy through the lateral fissure Rolandic point-insular lobe approach for patients with hypertensive intracerebral hemorrhage (HICH) in posterior basal gan…
View article: Exploring Chromatin Regulatory Factor Genes as Novel Biomarkers and Immunotherapy Targets through Multi-Omics Analysis in Kidney Renal Clear Cell Carcinoma to Uncover Tumor Heterogeneity
Exploring Chromatin Regulatory Factor Genes as Novel Biomarkers and Immunotherapy Targets through Multi-Omics Analysis in Kidney Renal Clear Cell Carcinoma to Uncover Tumor Heterogeneity Open
Background: Kidney Renal Clear Cell Carcinoma (KIRC) is the primary subtype of renal cell carcinoma, accounting for a significant proportion of cases, ranging from 75% to 80%, with a cancer-specific mortality rate as high as 24%. Despite s…
View article: Dislocation evolution in GaN-based Laser Diodes under nano-indentation
Dislocation evolution in GaN-based Laser Diodes under nano-indentation Open
The multiplication and motion behavior of dislocations induced by surface damage or the failure of devices in GaN-based LDs were simulated by nano-indentation technique. The results shown that dislocations with burgers vector of b = 1/3 < …
View article: Peripheral blood routine parameters-based MLP-ANN model discrimination of ulcerative colitis from Crohn's disease and prediction of disease activity
Peripheral blood routine parameters-based MLP-ANN model discrimination of ulcerative colitis from Crohn's disease and prediction of disease activity Open
Objective Peripheral blood routine parameters (PBRPs) are promising markers to reveal inflammatory response and immune function of patients with inflammatory bowel disease (IBD). Therefore, this study aimed to discriminate ulcerative colit…
View article: Hotspots and trends of electrochemical biosensor technology: a bibliometric analysis from 2003 to 2023
Hotspots and trends of electrochemical biosensor technology: a bibliometric analysis from 2003 to 2023 Open
In this paper, the research progress of electrochemical biosensors in the last twenty years is summarized using bibliometrics, and the research hotspots and development trends are determined to guide future research.
View article: Increased Fine Root Production Coupled with Reduced Aboveground Production of Plantations Under a Three-Year Experimental Drought
Increased Fine Root Production Coupled with Reduced Aboveground Production of Plantations Under a Three-Year Experimental Drought Open
View article: Drought Increases Fine Root Generation But Decreases Aboveground Production in a Poplar Forest Plantation
Drought Increases Fine Root Generation But Decreases Aboveground Production in a Poplar Forest Plantation Open
View article: Ultrasensitive and Rapid Electrochemical Detection of MiRNA-31 in Saliva Using Cas12a-Based 3D Nano-Harvester with Improved Trans-Cleavage Efficiency
Ultrasensitive and Rapid Electrochemical Detection of MiRNA-31 in Saliva Using Cas12a-Based 3D Nano-Harvester with Improved Trans-Cleavage Efficiency Open