Guoqing Du
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View article: Comment on “Bacterial extracellular vesicle as a predictive biomarker for postoperative delirium status after spinal surgery: a prospective cohort study”
Comment on “Bacterial extracellular vesicle as a predictive biomarker for postoperative delirium status after spinal surgery: a prospective cohort study” Open
View article: Comment on “The influence of familiarity between the surgeon and their assistant on patient outcomes: a prospective observational cohort study”
Comment on “The influence of familiarity between the surgeon and their assistant on patient outcomes: a prospective observational cohort study” Open
View article: Benefits of Simultaneous Pacing Left Anterior/Posterior Fascicular Areas Combined with Atrioventricular Node Ablation in a Persistent Atrial Fibrillation Patient with Heart Failure: A Case Report
Benefits of Simultaneous Pacing Left Anterior/Posterior Fascicular Areas Combined with Atrioventricular Node Ablation in a Persistent Atrial Fibrillation Patient with Heart Failure: A Case Report Open
A 50-year-old male had intermittent episodes of dyspnea for 7 days with persistent atrial fibrillation (AF) for 2 years. New York Heart Association (NYHA) functional class is IV status. The echocardiographic evaluation (Philps EPIQ 7C, S5-…
View article: A Transformer Based on Feedback Attention Mechanism for Diagnosis of Coronary Heart Disease Using Echocardiographic Images
A Transformer Based on Feedback Attention Mechanism for Diagnosis of Coronary Heart Disease Using Echocardiographic Images Open
View article: Exploring Bioinformatics Tools to Analyze the Role of CDC6 in the Progression of Polycystic Ovary Syndrome to Endometrial Cancer by Promoting Immune Infiltration
Exploring Bioinformatics Tools to Analyze the Role of CDC6 in the Progression of Polycystic Ovary Syndrome to Endometrial Cancer by Promoting Immune Infiltration Open
Cell division cycle 6 (CDC6) is essential for the initiation of DNA replication in eukaryotic cells and contributes to the development of various human tumors. Polycystic ovarian syndrome (PCOS) is a reproductive endocrine disease in women…
View article: Experimental Study on the Horizontal Bearing Characteristic of a Strip-Walled Underground Diaphragm Wall
Experimental Study on the Horizontal Bearing Characteristic of a Strip-Walled Underground Diaphragm Wall Open
Researching and developing a new type of diaphragm wall foundation can solve the probl em that the traditional diaphragm wall structure may not meet the high standards of safety and stability of underground structures in some specific engi…
View article: The molecular mechanism investigation of HBP-A slows down meniscus hypertrophy and mineralization by the damage mechanical model
The molecular mechanism investigation of HBP-A slows down meniscus hypertrophy and mineralization by the damage mechanical model Open
Objective This study aimed to determine if HBP-A slows down meniscus hypertrophy and mineralization due to abnormal mechanical damage and if the therapeutic effects of HBP-A are mediated through p38-MAPK signaling pathways. Methods In vivo…
View article: Left bundle branch area pacing combined with implantable cardioverter-defibrillator treatment for heart failure after myocardial infarction
Left bundle branch area pacing combined with implantable cardioverter-defibrillator treatment for heart failure after myocardial infarction Open
View article: Morphology and transverse alignment of the patella have no effect on knee gait characteristics in healthy Chinese adults over the age of 40 years
Morphology and transverse alignment of the patella have no effect on knee gait characteristics in healthy Chinese adults over the age of 40 years Open
Background: The influence of patella morphology and horizontal alignment on knee joint kinematics and kinetics remains uncertain. This study aimed to assess patella morphology and transverse alignment in relation to knee kinetics and kinem…
View article: Development of a prognostic model based on different disulfidptosis related genes typing for kidney renal clear cell carcinoma
Development of a prognostic model based on different disulfidptosis related genes typing for kidney renal clear cell carcinoma Open
Background: Kidney renal clear cell carcinoma (KIRC) is a common and clinically significant subtype of kidney cancer. A potential therapeutic target in KIRC is disulfidptosis, a novel mode of cell death induced by disulfide stress. The aim…
View article: PET-SQL: A Prompt-Enhanced Two-Round Refinement of Text-to-SQL with Cross-consistency
PET-SQL: A Prompt-Enhanced Two-Round Refinement of Text-to-SQL with Cross-consistency Open
Recent advancements in Text-to-SQL (Text2SQL) emphasize stimulating the large language models (LLM) on in-context learning, achieving significant results. Nevertheless, they face challenges when dealing with verbose database information an…
View article: The correlation between coagulation biomarkers, bone turnover markers, and bone mineral density in Chinese adults aged ≥ 50 years
The correlation between coagulation biomarkers, bone turnover markers, and bone mineral density in Chinese adults aged ≥ 50 years Open
Introduction Osteoporosis patients undergoing surgery often have significant bleeding, which is closely related to coagulation function. This study aimed to assess the correlation between bone turnover markers (BTMs), bone mineral density …
View article: Benchmarking the Text-to-SQL Capability of Large Language Models: A Comprehensive Evaluation
Benchmarking the Text-to-SQL Capability of Large Language Models: A Comprehensive Evaluation Open
Large Language Models (LLMs) have emerged as a powerful tool in advancing the Text-to-SQL task, significantly outperforming traditional methods. Nevertheless, as a nascent research field, there is still no consensus on the optimal prompt t…
View article: Right atrial papillary fibroelastoma arising from the Chiari network detected by echocardiography: a case report.
Right atrial papillary fibroelastoma arising from the Chiari network detected by echocardiography: a case report. Open
Right atrial papillary fibroelastomas (PFE) originated from the Chiari network (CN) are exceedingly rare. Only 2 cases have been reported in the worldwide literature. We present a case of PFE arising from the right atrial CN detected by tr…
View article: VisionTraj: A Noise-Robust Trajectory Recovery Framework based on Large-scale Camera Network
VisionTraj: A Noise-Robust Trajectory Recovery Framework based on Large-scale Camera Network Open
Trajectory recovery based on the snapshots from the city-wide multi-camera network facilitates urban mobility sensing and driveway optimization. The state-of-the-art solutions devoted to such a vision-based scheme typically incorporate pre…
View article: TPTU-v2: Boosting Task Planning and Tool Usage of Large Language Model-based Agents in Real-world Systems
TPTU-v2: Boosting Task Planning and Tool Usage of Large Language Model-based Agents in Real-world Systems Open
Large Language Models (LLMs) have demonstrated proficiency in addressing tasks that necessitate a combination of task planning and the usage of external tools that require a blend of task planning and the utilization of external tools, suc…
View article: Development and validation of a simple model to predict functionally significant coronary artery disease in Chinese populations: A two-center retrospective study
Development and validation of a simple model to predict functionally significant coronary artery disease in Chinese populations: A two-center retrospective study Open
View article: Efficacy and Safety of Lateral Position Rotation and Pulling Manipulation for Treating Low Back Pain of Sacroiliac Joint Misalignment Origin: Study Protocol for a Randomized Controlled Trial
Efficacy and Safety of Lateral Position Rotation and Pulling Manipulation for Treating Low Back Pain of Sacroiliac Joint Misalignment Origin: Study Protocol for a Randomized Controlled Trial Open
Background: Clinical studies have confirmed that traditional lumbar oblique-pulling manipulation (TLOM) can effectively improve lumbosacral pain caused by sacroiliac joint misalignment. However, the absence of established standards and no…
View article: Exploring the optimal impact force for chronic skeletal muscle injury induced by drop-mass technique in rats
Exploring the optimal impact force for chronic skeletal muscle injury induced by drop-mass technique in rats Open
Introduction: Skeletal muscle injuries are widespread in sports, traffic accidents and natural disasters and some of them with poor prognoses can lead to chronic skeletal muscle damage in the clinic. We induced a chronic skeletal muscle in…
View article: TPTU: Large Language Model-based AI Agents for Task Planning and Tool Usage
TPTU: Large Language Model-based AI Agents for Task Planning and Tool Usage Open
With recent advancements in natural language processing, Large Language Models (LLMs) have emerged as powerful tools for various real-world applications. Despite their prowess, the intrinsic generative abilities of LLMs may prove insuffici…
View article: Preclinical pharmacokinetic and pharmacodynamic evaluation of dasatinib and ponatinib for the treatment of T-cell acute lymphoblastic leukemia
Preclinical pharmacokinetic and pharmacodynamic evaluation of dasatinib and ponatinib for the treatment of T-cell acute lymphoblastic leukemia Open
View article: Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens
Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens Open
Bromo- and extra-terminal domain inhibitors (BETi) have exhibited therapeutic activities in many cancers. However, the mechanisms controlling BETi response and resistance are not well understood. We conducted genome-wide loss-of-function C…
View article: Data from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
Data from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel Open
Purpose: Docetaxel is extensively metabolized by CYP3A4 in the liver but mechanisms by which the drug is taken up into hepatocytes remain poorly understood. We hypothesized that (i) liver uptake of docetaxel is mediated by the polym…
View article: Supplementary Methods, Figures 1 - 4, Tables 1 - 3 from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
Supplementary Methods, Figures 1 - 4, Tables 1 - 3 from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel Open
PDF file, 437KB, Description of determination of docetaxel concentrations; influence of phenol red on OATP1B1-mediated transport of docetaxel; characterization of paclitaxel concentration-dependent transport by OATP1B1 and OATP1B3; docetax…
View article: Data from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
Data from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel Open
Purpose: Docetaxel is extensively metabolized by CYP3A4 in the liver but mechanisms by which the drug is taken up into hepatocytes remain poorly understood. We hypothesized that (i) liver uptake of docetaxel is mediated by the polym…
View article: Supplementary Materials and Methods from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Supplementary Materials and Methods from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues Open
This file contains supplementary information regarding materials and methods including: chemicals and reagents, early drug uptake, NCI60 correlation analysis, quantitative determination of ergothioneine, and culturing keratinocytes.
View article: Supplementary Figures and Tables from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Supplementary Figures and Tables from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues Open
This file contains supplementary information regarding materials and methods including: chemicals and reagents, early drug uptake, NCI60 correlation analysis, quantitative determination of ergothioneine, and culturing keratinocytes.
View article: Data from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Data from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues Open
Resistance to xenobiotic nucleosides used to treat acute myeloid leukemia (AML) and other cancers remains a major obstacle to clinical management. One process suggested to participate in resistance is reduced uptake into tumor cells via nu…
View article: Data from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Data from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues Open
Resistance to xenobiotic nucleosides used to treat acute myeloid leukemia (AML) and other cancers remains a major obstacle to clinical management. One process suggested to participate in resistance is reduced uptake into tumor cells via nu…
View article: Supplementary Figures and Tables from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues
Supplementary Figures and Tables from OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues Open
This file contains supplementary information regarding materials and methods including: chemicals and reagents, early drug uptake, NCI60 correlation analysis, quantitative determination of ergothioneine, and culturing keratinocytes.