Guoqiu Xu
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View article: Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis
Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis Open
Thiabendazole demonstrates promising anticancer potential in LUAD, influencing key genes and immune pathways. It may serve as an effective therapeutic agent targeting both cancer cells and the tumor microenvironment.
View article: Neoadjuvant Chemoimmunotherapy in Non-small-cell Lung Cancer Patients: Effects on Pulmonary Function and Incidence of Postoperative Pulmonary Complications—A Multicentre Real-World Study
Neoadjuvant Chemoimmunotherapy in Non-small-cell Lung Cancer Patients: Effects on Pulmonary Function and Incidence of Postoperative Pulmonary Complications—A Multicentre Real-World Study Open
Objectives To evaluate the effects of neoadjuvant chemoimmunotherapy on pulmonary function and the incidence of postoperative pulmonary complications in real-world non-small-cell lung cancer patients. Methods A retrospective analysis of st…
View article: The utility of three-dimensional computed tomography bronchography and angiography technology in pulmonary sequestration surgery
The utility of three-dimensional computed tomography bronchography and angiography technology in pulmonary sequestration surgery Open
Our findings preliminarily establish 3D-CTBA as a reliable strategy for PS surgery, effectively addressing the dual challenges of aberrant vessel identification and parenchymal preservation, particularly in complex cases (e.g., patients wi…
View article: Intraprocedural O-arm Computed Tomography guided Navigation with Ventilatory Strategy for Atelectasis Electromagnetic Navigation Bronchoscopic Biopsy of Peripheral Lung Lesions: an IDEAL stage 2a study
Intraprocedural O-arm Computed Tomography guided Navigation with Ventilatory Strategy for Atelectasis Electromagnetic Navigation Bronchoscopic Biopsy of Peripheral Lung Lesions: an IDEAL stage 2a study Open
Background: To improve the accuracy of electromagnetic navigation bronchoscopy (ENB) in the diagnosis of pulmonary nodules, we developed an innovative method to modify ENB, which first combines Intraprocedural Computed tomography (CT) guid…
View article: Intraprocedural computed tomography-guided navigation with ventilatory strategy for atelectasis (ICNVA): a modified electromagnetic navigation bronchoscopy
Intraprocedural computed tomography-guided navigation with ventilatory strategy for atelectasis (ICNVA): a modified electromagnetic navigation bronchoscopy Open
ICNVA-ENB can reduce the CT-body divergence and appears to be safe and accurate for patients with peripheral lung lesions.
View article: Intraprocedural CT guided Navigation with Ventilatory Strategy for Atelectasis (ICNVA): a modified electromagnetic navigation bronchoscopy
Intraprocedural CT guided Navigation with Ventilatory Strategy for Atelectasis (ICNVA): a modified electromagnetic navigation bronchoscopy Open
Background: CT-body divergence limits the accuracy of electromagnetic navigation bronchoscopy (ENB) in peripheral lung lesions diagnosis. We developed intraprocedural CT guided Navigation with Ventilatory Strategy for Atelectasis (ICNVA) E…
View article: Combining intraprocedural CT guided navigation with ventilatory strategy for atelectasis: A modified electromagnetic navigation bronchoscopy
Combining intraprocedural CT guided navigation with ventilatory strategy for atelectasis: A modified electromagnetic navigation bronchoscopy Open
CT-body divergence limits the accuracy of electromagnetic navigation bronchoscopy(ENB) in peripheral lung lesions diagnosis. Finding one effective and safe method to eliminating CT-body divergence may improve ENB accuracy. Thus, we develop…
View article: The Anti-Non-Small Cell Lung Cancer Cell Activity by a mTOR Kinase Inhibitor PQR620
The Anti-Non-Small Cell Lung Cancer Cell Activity by a mTOR Kinase Inhibitor PQR620 Open
In non-small-cell lung carcinoma (NSCLC), aberrant activation of mammalian target of rapamycin (mTOR) contributes to tumorigenesis and cancer progression. PQR620 is a novel and highly-potent mTOR kinase inhibitor. We here tested its potent…
View article: AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth
AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth Open
View article: One-stage video-assisted thoracic surgery for bilateral multiple pulmonary nodules
One-stage video-assisted thoracic surgery for bilateral multiple pulmonary nodules Open
Through rigorous preoperative assessment, it was demonstrated that one-stage VATS is safe and feasible for patients with BMPNs. Patients can avoid progression of the contralateral tumor, the trauma of the second operation, and the various …