G. Chen
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View article: 74P A single-center, phase II study of surufatinib combined with toripalimab, pemetrexed(A), and platinum (P) in patients with advanced non-squamous non-small cell lung cancer (nsq-NSCLC)
74P A single-center, phase II study of surufatinib combined with toripalimab, pemetrexed(A), and platinum (P) in patients with advanced non-squamous non-small cell lung cancer (nsq-NSCLC) Open
Surufatinib (S, a small-molecule inhibitor of VEGFR1-3, FGFR1 and CSF-1R) has exhibited encouraging efficacy in NSCLC patients (pts) as 3rd line or futher therapy in a phase II trial (NCT04922658). The purpose of this study is to evaluate …
View article: Nomogram for patients with stage I small cell lung cancer: A competing risk analysis
Nomogram for patients with stage I small cell lung cancer: A competing risk analysis Open
Background: Small-cell lung cancer (SCLC), accounting for about 15% of all lung cancers, is a subtype of lung cancer with poor prognosis. It has a 5-year survival rate of 7% and kills an estimated 250,000 people worldwide annually. Althoug…
View article: Education and lung cancer: A Mendelian randomisation study
Education and lung cancer: A Mendelian randomisation study Open
Background: Education has been shown to be inversely associated with the incidence of lung cancer at several conventional observational studies. However, this association may be biased owing to the methodological limitations of traditional…
View article: A Mendelian randomization study of the effects of Crohn’s disease on lung cancer
A Mendelian randomization study of the effects of Crohn’s disease on lung cancer Open
Background: Crohn's disease is associated with increased lung cancer risk in observational studies, but the causality of this association is uncertain. Here we conducted a two-sample Mendelian randomisation (MR) study to examine whether Cr…