Guang‐Hui Zhao
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View article: LncRNA BACE1-AS delays the propagation of <i>Cryptosporidium parvum</i> through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis
LncRNA BACE1-AS delays the propagation of <i>Cryptosporidium parvum</i> through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis Open
Cryptosporidium spp. are important zoonotic pathogens causing diarrhea in humans and various animals. To date, there are still no effective drugs and vaccines for the prevention and treatment of cryptosporidiosis, mainly due to the absence…
View article: Neospora caninum hijacks host PFKFB3-driven glycolysis to facilitate intracellular propagation of parasites
Neospora caninum hijacks host PFKFB3-driven glycolysis to facilitate intracellular propagation of parasites Open
View article: Pathology of fatal <i>Baylisascaris schroederi</i> infection in a wild giant panda
Pathology of fatal <i>Baylisascaris schroederi</i> infection in a wild giant panda Open
Baylisascaris schroederi McIntosh, 1939 (Ascarididae), a nematode specific to giant pandas ( Ailuropoda melanoleuca ), is a major health threat, particularly to wild populations. A 20-year-old wild adult female giant panda rescued from a C…
View article: <i>Neospora caninum</i> infection specifically suppresses the expression of a host lncRNA <i>XR_001919077.1</i> to facilitate parasite propagation by modulating host cell mitochondrial function and autophagy
<i>Neospora caninum</i> infection specifically suppresses the expression of a host lncRNA <i>XR_001919077.1</i> to facilitate parasite propagation by modulating host cell mitochondrial function and autophagy Open
Neospora caninum is one of the most common pathogens causing reproductive failure in ruminants (e.g., cattle and goats) worldwide. However, due to a poor understanding of the pathogenic mechanisms of N. caninum infection, no effective drug…
View article: Single-cell RNA-sequencing reveals a unique landscape of the tumor microenvironment in obesity-associated breast cancer
Single-cell RNA-sequencing reveals a unique landscape of the tumor microenvironment in obesity-associated breast cancer Open
View article: Epidemiological Survey on Tick Borne Diseases of Pet Dogs in Korla, Northwestern China
Epidemiological Survey on Tick Borne Diseases of Pet Dogs in Korla, Northwestern China Open
Pet dogs pose a potential risk to transmitting zoonotic pathogens by ticks. However information about the prevalence status in pet dogs of tick-borne diseases is currently limited. In this study, 196 blood samples and 223 ticks were collec…
View article: Wild sympatric rodents inhabiting pig farm environments may facilitate the spillover of <i>Enterocytozoon bieneusi</i> from pig farms
Wild sympatric rodents inhabiting pig farm environments may facilitate the spillover of <i>Enterocytozoon bieneusi</i> from pig farms Open
Enterocytozoon bieneusi is a zoonotic pathogen prevalent in mammalian and avian hosts across the globe. Wild small mammals, being abundant worldwide, serve as important sources of zoonotic disease transmission to humans. Here, 227 fecal sa…
View article: Molecular Characterization of Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and Escherichia coli in Dairy Goat Kids with Diarrhea in Partial Regions of Shaanxi Province, China
Molecular Characterization of Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and Escherichia coli in Dairy Goat Kids with Diarrhea in Partial Regions of Shaanxi Province, China Open
Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and Escherichia coli are important diarrheal pathogens threatening the health of humans and various animals. Goats, especially pre-weaned goat kids, that carry these pathoge…
View article: C3a/C3aR Affects the Propagation of Cryptosporidium parvum in the Ileum Tissues of Mice by Regulating the Gut Barrier, Cell Proliferation, and CD4+ T Cell Main Effectors
C3a/C3aR Affects the Propagation of Cryptosporidium parvum in the Ileum Tissues of Mice by Regulating the Gut Barrier, Cell Proliferation, and CD4+ T Cell Main Effectors Open
Cryptosporidium parvum is an important zoonotic protozoon that threatens the health of humans and animals, but the interaction mechanisms between C. parvum and hosts are poorly understood. Our previous study indicated that the expression l…
View article: Single-Cell RNA-Sequencing Reveals a Unique Landscape of the Tumor Microenvironment in Obesity-Associated Breast Cancer
Single-Cell RNA-Sequencing Reveals a Unique Landscape of the Tumor Microenvironment in Obesity-Associated Breast Cancer Open
View article: High genotype diversity and zoonotic potential of <i>Enterocytozoon bieneusi</i> in yaks (<i>Bos grunniens</i>) from Ganzi Tibetan Autonomous Prefecture, Sichuan Province
High genotype diversity and zoonotic potential of <i>Enterocytozoon bieneusi</i> in yaks (<i>Bos grunniens</i>) from Ganzi Tibetan Autonomous Prefecture, Sichuan Province Open
Enterocytozoon bieneusi is a common pathogen in humans and various animals, threatening the breeding industry and public health. However, there is limited information on the molecular characteristics of E. bieneusi in yaks, an economically…
View article: Development and Preliminary Evaluation of a Nanoparticle-Assisted PCR Assay for the Detection of Cryptosporidium parvum in Calves
Development and Preliminary Evaluation of a Nanoparticle-Assisted PCR Assay for the Detection of Cryptosporidium parvum in Calves Open
C. parvum is an important diarrheal pathogen in humans and animals, especially in young hosts. To accurately and rapidly detect C. parvum infection in calves, we established a nano-PCR assay targeting the cgd3_330 gene for the specific det…
View article: Molecular Characterization of Anaplasma spp. among Dairy, Cashmere, and Meat Goats in Shaanxi Province, Northwestern China
Molecular Characterization of Anaplasma spp. among Dairy, Cashmere, and Meat Goats in Shaanxi Province, Northwestern China Open
Anaplasma spp. are important tick-borne pathogens endangering the health of humans and various animals. Although several studies have reported Anaplasma infection in livestock in China, little is known about the impact of production catego…
View article: Molecular Characterization of 18S rDNA, ITS-1, ITS-2, and COI from Eimeria christenseni and E. arloingi in Goats from Shaanxi Province, Northwestern China
Molecular Characterization of 18S rDNA, ITS-1, ITS-2, and COI from Eimeria christenseni and E. arloingi in Goats from Shaanxi Province, Northwestern China Open
Coccidiosis caused by Eimeria is one of the most common and significant diseases in goats, leading to serious economic losses in the development of the goat industry. Although several genetic loci, such as 18S rDNA, ITS-1, ITS-2, and COI, …
View article: Additional file 5 of RNA sequencing reveals dynamic expression of lncRNAs and mRNAs in caprine endometrial epithelial cells induced by Neospora caninum infection
Additional file 5 of RNA sequencing reveals dynamic expression of lncRNAs and mRNAs in caprine endometrial epithelial cells induced by Neospora caninum infection Open
Additional file 5: Data S5. All differentially expressed mRNAs (DEmRNAs).
View article: Molecular Characterization of Blastocystis sp. in Camelus bactrianus in Northwestern China
Molecular Characterization of Blastocystis sp. in Camelus bactrianus in Northwestern China Open
Blastocystis sp. is an important zoonotic protist in humans and various animals with worldwide distribution. However, there have been no data on the occurrence of Blastocystis sp. in C. bactrianus, an important economic animal in northwest…
View article: Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
View article: Orchid mantis ambushes foraging butterflies
Orchid mantis ambushes foraging butterflies Open
The orchid mantis, Hymenopus coronatus, which inhabits Southeast Asia, has a unique flower-like appearance that allows it to ambush unsuspecting floral visitors. After more than a century of conjecture, O'Hanlon et al. provided the first e…
View article: Additional file 9 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 9 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 9: Data S9. The GO and KEGG pathway enrichment analysis of trans-targets for the differentially expressed lncRNAs.
View article: Additional file 7 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 7 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 7: Data S7. The GO and KEGG pathway enrichment analysis of target genes for the differentially expressed lncRNAs.
View article: Additional file 6 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 6 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 6: Data S6. The sponging miRNAs predicted for differentially expressed circRNAs and their potential targets.
View article: Additional file 3 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 3 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 3: Data S3. The length distribution of lncRNAs and circRNAs.
View article: Additional file 5 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 5 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 5: Data S5. The cis- and trans-target genes predicted for differentially expressed lncRNAs.
View article: Additional file 1 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 1 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 1: Data S1. The primers used for verification of differentially expressed mRNAs, lncRNAs and circRNAs by qRT-PCR.
View article: Additional file 11 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 11 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 11: Data S11. The GO and KEGG pathway enrichment analysis of sponging miRNA targets for the differentially expressed circRNAs.
View article: Additional file 8 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 8 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 8: Data S8. The GO and KEGG pathway enrichment analysis of cis-target genes for the differentially expressed lncRNAs.
View article: Additional file 4 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 4 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 4: Data S4. The target genes predicted for differentially expressed lncRNAs.
View article: Additional file 2 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 2 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 2: Data S2. All the expressed mRNAs, lncRNAs and circRNAs in this study.
View article: Additional file 10 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection
Additional file 10 of Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs in chickens during Eimeria necatrix infection Open
Additional file 10: Data S10. The GO and KEGG pathway enrichment analysis of source genes for the differentially expressed circRNAs.
View article: Differential Brain MicroRNA Expression Profiles After Acute and Chronic Infection of Mice With Toxoplasma gondii Oocysts
Differential Brain MicroRNA Expression Profiles After Acute and Chronic Infection of Mice With Toxoplasma gondii Oocysts Open
Brain microRNAs (miRNAs) change in abundance in response to Toxoplasma gondii infection. However, their precise role in the pathogenesis of cerebral infection with T. gondii oocyst remains unclear. We studied the abundance of…