Sachin Gupta
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View article: Risk of Cardiovascular Events Using the SMART Polyvascular Disease Risk Score
Risk of Cardiovascular Events Using the SMART Polyvascular Disease Risk Score Open
Background Secondary Manifestations of Arterial Disease (SMART) risk score based projection of risk for cardiovascular (CV) events can help devise risk mitigation strategies. Objective Use of the SMART polyvascular disease score to compute…
View article: Author Response: Bridging Gaps in Fluid Choices and Management in Critically Ill Patients
Author Response: Bridging Gaps in Fluid Choices and Management in Critically Ill Patients Open
View article: F-76 | C-Reactive Protein and Clinical Outcomes of Endovascular Intervention in Patients with Symptomatic Peripheral Artery Disease From The XLPAD Registry
F-76 | C-Reactive Protein and Clinical Outcomes of Endovascular Intervention in Patients with Symptomatic Peripheral Artery Disease From The XLPAD Registry Open
View article: F-72 | Duration of Dual Anti-Platelet Therapy and Major Adverse Limb Outcomes of Endovascular Intervention for Symptomatic Peripheral Artery Disease from The XLPAD Registry
F-72 | Duration of Dual Anti-Platelet Therapy and Major Adverse Limb Outcomes of Endovascular Intervention for Symptomatic Peripheral Artery Disease from The XLPAD Registry Open
View article: Management of Newborn Respiratory Distress Using CPAP: Capacity and Readiness of Public Health Facilities in High-Focus Aspirational Districts of India
Management of Newborn Respiratory Distress Using CPAP: Capacity and Readiness of Public Health Facilities in High-Focus Aspirational Districts of India Open
Background and Objective Adequate respiratory support is crucial for managing respiratory distress in hypoxic newborns. Continuous positive airway pressure (CPAP) devices are widely recommended for this purpose, but their availability and …
View article: Cannabis abuse and spinal Anesthesia-A case series
Cannabis abuse and spinal Anesthesia-A case series Open
View article: Salt Based or BaLanced SolUtion–Trends Existing in Indian Intensive Care Units: A Multicenter Prospective Observational Cohort Study (SOLUTE Study)
Salt Based or BaLanced SolUtion–Trends Existing in Indian Intensive Care Units: A Multicenter Prospective Observational Cohort Study (SOLUTE Study) Open
Gupta S, Dixit S, Tomar DS, Zirpe K, Govil D, Choudhry D, et al. Salt Based or BaLanced SolUtion-Trends Existing in Indian Intensive Care Units: A Multicenter Prospective Observational Cohort Study (SOLUTE Study). Indian J Crit Care…
View article: ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit
ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit Open
Bhattacharya PK, Chakrabarti A, Sinha S, Pande R, Gupta S, Kumar AAK, et al. ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit. Indian J Crit Care Med 2024;28(S2):S20-S41.
View article: TRICHOBEZOAR-A RARE CAUSE OF ABDOMINAL MASS AND GASTRIC OUTLET OBSTRUCTION
TRICHOBEZOAR-A RARE CAUSE OF ABDOMINAL MASS AND GASTRIC OUTLET OBSTRUCTION Open
The authors present the clinical case of a 18 -year old girl with weight loss,anorexia,epigastric abdominal pain and post prandial vomiting with 4 months duration.There was a background of trichophagia for 5-6 years without evidence of alo…
View article: Am I Sedated or in Pain? Please Monitor by Brain
Am I Sedated or in Pain? Please Monitor by Brain Open
How to cite this article: Gupta A, Tomar DS. Am I Sedated or in Pain? Please Monitor by Brain. Indian J Crit Care Med 2024;28(6):531-532.
View article: Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry Open
Introduction Pulmonary fibrosis is a characteristic of various interstitial lung diseases (ILDs) with differing etiologies. Clinical trials in progressive pulmonary fibrosis (PPF) enroll patients based on previously described clinical crit…
View article: VENT-AVOID Trial: Avoiding Acute Hypercapnic Respiratory Failure!
VENT-AVOID Trial: Avoiding Acute Hypercapnic Respiratory Failure! Open
"VENT-AVOID Trial – Avoiding Acute Hypercapnic Respiratory Failure!." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
View article: Peripheral nerve‐derived <scp>Sema3A</scp> promotes osteogenic differentiation of mesenchymal stem cells through the Wnt/β‐catenin/Nrp1 positive feedback loop
Peripheral nerve‐derived <span>Sema3A</span> promotes osteogenic differentiation of mesenchymal stem cells through the Wnt/β‐catenin/Nrp1 positive feedback loop Open
Sensory nerves play a crucial role in maintaining bone homeostasis by releasing Semaphorin 3A (Sema3A). However, the specific mechanism of Sema3A in regulation of bone marrow mesenchymal stem cells (BMMSCs) during bone remodelling remains …
View article: Systematic review with expert consensus on use of extracorporeal hemoadsorption in septic shock: An Indian perspective
Systematic review with expert consensus on use of extracorporeal hemoadsorption in septic shock: An Indian perspective Open
BACKGROUND Septic shock is a severe form of sepsis characterised by deterioration in circulatory and cellular-metabolic parameters. Despite standard therapy, the outcomes are poor. Newer adjuvant therapy, such as CytoSorb® extracorporeal h…
View article: Acute Kidney Injury and ECMO: Two Sides of the Same Coin
Acute Kidney Injury and ECMO: Two Sides of the Same Coin Open
How to cite this article: Gupta S, Tomar DS. Acute Kidney Injury and ECMO: Two Sides of the Same Coin. Indian J Crit Care Med 2024;28(1):3-4.
View article: A randomised prospective study to assess the analgesic efficacy of peripheral nerve block using ropivacaine with dexamethasone vs. dexmedetomidine for postoperative analgesia in lower limb surgeries
A randomised prospective study to assess the analgesic efficacy of peripheral nerve block using ropivacaine with dexamethasone vs. dexmedetomidine for postoperative analgesia in lower limb surgeries Open
The use of peripheral nerve blocks using local anaesthesia along with adjuvant helps in pain relief for longer duration. It is the key to enhance clinical rehabilitation as an important part of the multimodal analgesia scheme. Aim and obje…
View article: Ceftazidime-avibactam alone or in combination with Aztreonam versus Polymyxins in the management of carbapenem-Resistant Klebsiella pneumoniae nosocomial Infections (CAPRI study): a retrospective cohort study from South India
Ceftazidime-avibactam alone or in combination with Aztreonam versus Polymyxins in the management of carbapenem-Resistant Klebsiella pneumoniae nosocomial Infections (CAPRI study): a retrospective cohort study from South India Open
Introduction Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections commonly cause hospital-acquired infections. The study aimed to compare the outcomes of CRKP infections between patients receiving ceftazidime avibactam +/− aztreona…
View article: Evaluation of the safety and efficacy of extracorporeal carbon dioxide removal in the critically ill using the PrismaLung+ device
Evaluation of the safety and efficacy of extracorporeal carbon dioxide removal in the critically ill using the PrismaLung+ device Open
View article: Identification of Functional Modules and Key Pathways Associated with Innervation in Graft Bone—CGRP Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via p38 MAPK and Wnt6/β-Catenin
Identification of Functional Modules and Key Pathways Associated with Innervation in Graft Bone—CGRP Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via p38 MAPK and Wnt6/β-Catenin Open
Bone resorption occurs after bone grafting, however, contemporaneous reconstruction of the innervation of the bone graft is a potential treatment to maintain the bone mass of the graft. The innervation of bone is an emerging research topic…
View article: Diagnostic Shift from Gall Bladder Carcinoma to Periampullary Tumor Owing to Xanthogranulomatous Cholecystitis: A Narrow Escape
Diagnostic Shift from Gall Bladder Carcinoma to Periampullary Tumor Owing to Xanthogranulomatous Cholecystitis: A Narrow Escape Open
Xanthogranulomatous cholecystitis (XGC) is an inflammatory disease and uncommon variant of chronic cholecystitis [1].Focal or diffuse destructive inflammatory process followed by marked proliferative fibrosis along with infiltration of mac…
View article: Influenza A (H1N1): Now is it a Thing of the Past?
Influenza A (H1N1): Now is it a Thing of the Past? Open
How to cite this article: Gupta S, Tomar DS. Influenza A (H1N1): Now is it a Thing of the Past? Indian J Crit Care Med 2023;27(7):461-462.
View article: <scp>CSF</scp> neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in <scp>FIRES</scp> and other infection‐triggered encephalopathy syndromes
<span>CSF</span> neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in <span>FIRES</span> and other infection‐triggered encephalopathy syndromes Open
Objective Infection‐triggered encephalopathy syndromes (ITES) are potentially devastating neuroinflammatory conditions. Although some ITES syndromes have recognisable MRI neuroimaging phenotypes, there are otherwise few biomarkers of disea…
View article: Successful Use of Cefepime-Zidebactam (WCK 5222) as a Salvage Therapy for the Treatment of Disseminated Extensively Drug-Resistant New Delhi Metallo-β-Lactamase-Producing Pseudomonas aeruginosa Infection in an Adult Patient with Acute T-Cell Leukemia
Successful Use of Cefepime-Zidebactam (WCK 5222) as a Salvage Therapy for the Treatment of Disseminated Extensively Drug-Resistant New Delhi Metallo-β-Lactamase-Producing Pseudomonas aeruginosa Infection in an Adult Patient with Acute T-Cell Leukemia Open
With limited and often toxic treatment options, carbapenem-resistant Gram-negative infections are associated with significant mortality. Cefepime-zidebactam is a promising antibiotic option undergoing a phase 3 trial that has activity agai…
View article: Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study
Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study Open
Approximately one in six IHCA patients fulfilled E-CPR selection criteria during IHCA, half of whom had a poor outcome. Non-shockable rhythm and longer duration of CPR were associated with poor outcome. Patients who had CPR for >15 minutes…
View article: CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation
CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation Open
View article: Frontiers of Hydroxyapatite Composites in Bionic Bone Tissue Engineering
Frontiers of Hydroxyapatite Composites in Bionic Bone Tissue Engineering Open
Bone defects caused by various factors may cause morphological and functional disorders that can seriously affect patient’s quality of life. Autologous bone grafting is morbid, involves numerous complications, and provides limited volume a…
View article: Indian Journal of Critical Care Medicine
Indian Journal of Critical Care Medicine Open
How to cite this article: Srinivasan S, Kumar PG, Govil D, Gupta S, Kumar V, Pichamuthu K, et al. Competencies for Point-of-care Ultrasonography in ICU: An ISCCM Expert Panel Practice Recommendation. Indian J Crit Care Med 20…
View article: Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids
Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids Open
View article: P11.38.A Case reports on aggressive Pilocytic astrocytoma in TYA and adults: patient tailored approach or standard of care?
P11.38.A Case reports on aggressive Pilocytic astrocytoma in TYA and adults: patient tailored approach or standard of care? Open
Background Pilocytic astrocytoma (piloA) is a low grade brain tumour and most of the literature is based on paediatric patients with limited data on adults. Surgical resection followed by adjuvant treatment for recurrent lesions is standar…
View article: Operative Technique: Angiomatoid Fibrous Histiocytoma—Unique Case and Management
Operative Technique: Angiomatoid Fibrous Histiocytoma—Unique Case and Management Open
Objective We describe the first jugular foramen angiomatoid fibrous histiocytoma (AFH) case and the first treatment with preoperative endovascular embolization. AFH is a rare intracranial neoplasm, primarily found in pediatric patient extr…