Gurjaspreet Singh
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View article: Schiff Base–Tethered Silane as a Trifunctional Probe for Selective Ni <sup>2</sup> ⁺ Sensing, Antioxidant Activity, and Molecular Docking
Schiff Base–Tethered Silane as a Trifunctional Probe for Selective Ni <sup>2</sup> ⁺ Sensing, Antioxidant Activity, and Molecular Docking Open
In this study, a new Schiff base‐functionalized silane, compound 3, derived from 4‐(pyridin‐2‐yl)benzaldehyde, was synthesized and comprehensively characterized using 1 H NMR, 13 C NMR, and mass spectrometry. The optical properties of comp…
View article: Silatrane‐Linked Schiff Base Triazole for Al (III) Detection: Bridging Photophysical Studies with Biological Activity and Molecular Docking Insights
Silatrane‐Linked Schiff Base Triazole for Al (III) Detection: Bridging Photophysical Studies with Biological Activity and Molecular Docking Insights Open
In the current work, modified Schiff base triazole appended silatrane (6) has been synthesized using the copper(I) catalyzed alkyne azide cycloaddition (CuAAC) approach. The organosilatrane (6) has been utilized for the detection of Al (II…
View article: Understanding the working of magnetic COFs in the extraction and determination of target contaminants for food safety
Understanding the working of magnetic COFs in the extraction and determination of target contaminants for food safety Open
Rising food safety concerns necessitate sensitive, rapid, and reliable analytical methods for contaminant detection. Covalent organic frameworks (COFs), especially magnetic COF composites, have emerged as powerful sorbents for sample prepa…
View article: Correction to: Click Chemistry Synthesis of Tetrazole linked Organosilanes and Organosilatranes: A computational Evaluation of Pharmacokinetics, Bioactivity, and Acetylcholinesterase (AChE) Inhibition for Alzheimer’s Treatment
Correction to: Click Chemistry Synthesis of Tetrazole linked Organosilanes and Organosilatranes: A computational Evaluation of Pharmacokinetics, Bioactivity, and Acetylcholinesterase (AChE) Inhibition for Alzheimer’s Treatment Open
View article: Alkyne Allied Schiff‐Base Synthesis for the Tin(II) Detection via UV–Visible and Fluorescence Sensor Along With Their Cytotoxicity Assessment and Antibreast Cancer Activity Against 17Beta‐HSD1 Using Molecular Docking
Alkyne Allied Schiff‐Base Synthesis for the Tin(II) Detection via UV–Visible and Fluorescence Sensor Along With Their Cytotoxicity Assessment and Antibreast Cancer Activity Against 17Beta‐HSD1 Using Molecular Docking Open
Breast cancer continues to be a devastating disease worldwide, highlighting the critical need for new and effective treatments. Schiff bases are increasingly being used as powerful medications for a number of disorders. The current investi…
View article: pH‐Dependent Chromogenic and Smartphone‐Assisted Detection of Fe(III) by Acid‐Sensitive 1,2‐Biphenyl‐Substituted Benzimidazole 1,2,3‐Triazole Hybrids: In Vitro Anticancer Property Evaluation and In Silico Inhibition of Breast Cancer Estrogen Receptor Mutant L536S
pH‐Dependent Chromogenic and Smartphone‐Assisted Detection of Fe(III) by Acid‐Sensitive 1,2‐Biphenyl‐Substituted Benzimidazole 1,2,3‐Triazole Hybrids: In Vitro Anticancer Property Evaluation and In Silico Inhibition of Breast Cancer Estrogen Receptor Mutant L536S Open
The detection of Fe(III) ions and monitoring of pH conditions are vital for safety, efficiency, and sustainability in scientific research, environmental management, and industrial applications. In this study, two 1,2‐biphenyl‐substituted b…
View article: Benzyloxyaniline Derived Schiff Base as an Effective Tool for Colorimetric Al(III) Sensing and Potency Against Aluminium Toxicity
Benzyloxyaniline Derived Schiff Base as an Effective Tool for Colorimetric Al(III) Sensing and Potency Against Aluminium Toxicity Open
Heavy metal pollution poses significant environmental threats due to the non‐biodegradable, persistent, and toxic nature of these metals. They accumulate in various environmental components, leading to contamination of water, soil, and air…
View article: Pyrrolidine‐Derived 1,2,3‐Triazolyl Organosilane as ‘Turn‐On’ Fluorescence Sensor for Zn(II) Ion: Synthesis, Antioxidant, Molecular Docking and DFT Studies
Pyrrolidine‐Derived 1,2,3‐Triazolyl Organosilane as ‘Turn‐On’ Fluorescence Sensor for Zn(II) Ion: Synthesis, Antioxidant, Molecular Docking and DFT Studies Open
The article emphasises the synthesis of pyrrolidine‐derived 1,2,3‐triazolyl organosilane 5 which was well characterised by utilising spectroscopic techniques such as NMR ( 1 H and 13 C), IR, elemental analysis, UV–visible, fluorescence and…
View article: Selective metal ion recognition <i>via</i> positional isomers: fluorescent chalcone-1,2,3-triazole hybrids for Co( <scp>ii</scp> ) and Cu( <scp>ii</scp> ) detection
Selective metal ion recognition <i>via</i> positional isomers: fluorescent chalcone-1,2,3-triazole hybrids for Co( <span>ii</span> ) and Cu( <span>ii</span> ) detection Open
Three new chalcone-based 1,2,3-triazole derivatives (positional isomers) have been synthesised using ‘CuAAC’ for Co( ii ) and Cu( ii ) ion detection.
View article: Detecting cancer biomarkers using electrochemical composite nanomaterials tools
Detecting cancer biomarkers using electrochemical composite nanomaterials tools Open
Annually, cancer accounts for a large number of mortalities worldwide, underscoring the imperative for early‐stage detection as a public health priority. This article not only offers an in‐depth analysis of the synthesis, fabrication, desi…
View article: Heavy metal ions monitoring using molecular ligands: Optical properties and analytical performances
Heavy metal ions monitoring using molecular ligands: Optical properties and analytical performances Open
Heavy metal ions are resistant to degradation and pollute a wide range of natural resources found in the environment, such as water. Detecting heavy metals is crucial for monitoring environmental safety and preventing the harmful effects o…
View article: Unveiling the ion sensing capabailities of ‘click’ derived chalcone-tailored 1,2,3-triazolic isomers for Pb( <scp>ii</scp> ) and Cu( <scp>ii</scp> ) ions: DFT analysis
Unveiling the ion sensing capabailities of ‘click’ derived chalcone-tailored 1,2,3-triazolic isomers for Pb( <span>ii</span> ) and Cu( <span>ii</span> ) ions: DFT analysis Open
Two new chalcone-based 1,2,3-triazole derivatives have been synthesised using ‘CuAAC’ for Cu( ii ) and Pb( ii ) ion detection.
View article: Ni@Fe3o4/L-Alanine-Acrylamide Nanocomposite Catalyzed Suzuki Transformation Reactions and Estrogen Inhibitory Activity: Experimental and Docking Investigation
Ni@Fe3o4/L-Alanine-Acrylamide Nanocomposite Catalyzed Suzuki Transformation Reactions and Estrogen Inhibitory Activity: Experimental and Docking Investigation Open
View article: ‘Turn On’ Fluorescent Imine Linked 1,2,3-Triazole Based Chemosensor for Detection of Mercuric Ions
‘Turn On’ Fluorescent Imine Linked 1,2,3-Triazole Based Chemosensor for Detection of Mercuric Ions Open
View article: Metal oxide nanoparticles as efficient catalysts for biodiesel production
Metal oxide nanoparticles as efficient catalysts for biodiesel production Open
Currently, a lot of effort has been carried for the development of an alternate fuel to meet with the energy requirement and transportation vehicle system of the World. In this regard, one of the most promising alternates, that have been u…
View article: Harnessing Nature: Silver Nanoparticles from Uraria Picta as an Alternative Cryptosporidiosis Therapy
Harnessing Nature: Silver Nanoparticles from Uraria Picta as an Alternative Cryptosporidiosis Therapy Open
View article: Harnessing Nature: Silver Nanoparticles from <i>Uraria Picta</i> as an Alternative Cryptosporidiosis Therapy
Harnessing Nature: Silver Nanoparticles from <i>Uraria Picta</i> as an Alternative Cryptosporidiosis Therapy Open
View article: Clicking in harmony: exploring the bio-orthogonal overlap in click chemistry
Clicking in harmony: exploring the bio-orthogonal overlap in click chemistry Open
The fundamentals of bio-orthogonal click chemistry are investigated, while exploring mechanistic intricacies, demonstrating the adaptability and promise of this methodology.
View article: Extractive spectrophotometric detection of Sn(II) using 6-bromo-3-hydroxy-2- (5-methylfuran-2-yl)-4H-chromen-4-one
Extractive spectrophotometric detection of Sn(II) using 6-bromo-3-hydroxy-2- (5-methylfuran-2-yl)-4H-chromen-4-one Open
For the determination of tin(II) traces, an extractive spectrophotometric approach is devised. The applied method serves a powerful tool for determination of tin(II), involves the formation of yellow colored complex among the 6-bromo-3-hyd…
View article: Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate
Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate Open
Over the years, ground and surface water has been reported to be contaminated with phosphates. These phosphates are known to cause various diseases and if present in excess can lead to eutrophication. The known silane chemistry has not bee…
View article: Covalent organic frameworks (COFs) and metal–organic frameworks (MOFs) as electrochemical sensors for the efficient detection of pharmaceutical residues
Covalent organic frameworks (COFs) and metal–organic frameworks (MOFs) as electrochemical sensors for the efficient detection of pharmaceutical residues Open
Pharmaceutical residues are the undecomposed remains from drugs used in the medical and food industries. Due to their potential adverse effects on human health and natural ecosystems, they are of increasing worldwide concern. The acute det…
View article: Copper-Based Metal–Organic Frameworks (MOFs) as an Emerging Catalytic Framework for Click Chemistry
Copper-Based Metal–Organic Frameworks (MOFs) as an Emerging Catalytic Framework for Click Chemistry Open
In the extensive terrain of catalytic procedures for the synthesis of organic molecules, metal–organic frameworks (MOFs) as heterogenous catalysts have been investigated in a variety of chemical processes, including Friedel–Crafts reaction…
View article: CuAAC ensembled 1,2,3-triazole linked nanogels for targeted drug delivery: a review
CuAAC ensembled 1,2,3-triazole linked nanogels for targeted drug delivery: a review Open
Copper( i ) catalyzed alkyne azide cycloaddition is the quintessential example of ‘Click Chemistry’, provides an adaptable platform for the synthesis of nanogels for sustained drug release at targeted sites owing to their better biocompati…
View article: ‘Click’-Synthesized Pet Based Fluorescent Sensor for Hg(Ii), Pb(Ii) and Cr(Iii) Recognition: Dft and Docking Studies
‘Click’-Synthesized Pet Based Fluorescent Sensor for Hg(Ii), Pb(Ii) and Cr(Iii) Recognition: Dft and Docking Studies Open
View article: Correction: Heterocycle-derived organosilatranes as naked eye sensors for Sn<sup>2+</sup> ions and their potential inhibiting activity against HIV-1 protease <i>via</i> a computational approach
Correction: Heterocycle-derived organosilatranes as naked eye sensors for Sn<sup>2+</sup> ions and their potential inhibiting activity against HIV-1 protease <i>via</i> a computational approach Open
Correction for ‘Heterocycle-derived organosilatranes as naked eye sensors for Sn 2+ ions and their potential inhibiting activity against HIV-1 protease via a computational approach’ by Gurjaspreet Singh et al. , New J. Chem. , 2023, 47 , 1…
View article: Cu( <scp>i</scp> )-catalysed 1,2,3-triazole stitched chalcomer assembly as Pb( <scp>ii</scp> ) and Cu( <scp>ii</scp> ) ion sensor: DFT and docking scrutiny
Cu( <span>i</span> )-catalysed 1,2,3-triazole stitched chalcomer assembly as Pb( <span>ii</span> ) and Cu( <span>ii</span> ) ion sensor: DFT and docking scrutiny Open
1,2,3-triazole derivative (CBT) was synthesized using the CuAAC procedure, with chalcone skeleton and was implemented as an effective sensor for Pb( ii ) and Cu( ii ) ions.
View article: CuAAC-Derived Selective Fluorescent Probe as a Recognition Agent for Pb(II) and Hg(II): DFT and Docking Studies
CuAAC-Derived Selective Fluorescent Probe as a Recognition Agent for Pb(II) and Hg(II): DFT and Docking Studies Open
Copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) is a resourceful and stereospecific methodology that has considerably yielded promising 1,2,3-triazole-appended "click" scaffolds with the potential for selective metal ion recognition…
View article: CCDC 2000473: Experimental Crystal Structure Determination
CCDC 2000473: Experimental Crystal Structure Determination Open
View article: Design, Synthesis, Drug-Likeness And In Silico Prediction of Polycyclic Aromatic Schiff Base Tethered Organosilatranes
Design, Synthesis, Drug-Likeness And In Silico Prediction of Polycyclic Aromatic Schiff Base Tethered Organosilatranes Open
The present article includes the generation of aromatic Schiff base tethered organosilatranes via two step synthetic pathways starting from anthracene-10-carbaldehyde and 1H-indole-3-carbaldehyde. The synthesis was achieved by employing co…
View article: Design of new bis-triazolyl structure for identification of inhibitory activity on COVID-19 main protease by molecular docking approach
Design of new bis-triazolyl structure for identification of inhibitory activity on COVID-19 main protease by molecular docking approach Open