Guruprasad Krishnamoorthy
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View article: Variable density and anisotropic field-of-view for 3D Stack-of-Stars radial imaging
Variable density and anisotropic field-of-view for 3D Stack-of-Stars radial imaging Open
Objective To develop a non-iterative method for applying elliptical field-of-view (FOV) to radial imaging and evaluate it for Stack-Of-Stars (SOS) with variable radial density in the $${k}_{z}$$ direction. Materials and methods New ana…
View article: Exact, time‐dependent analytical equations for spiral trajectories and matching gradient and density‐correction waveforms
Exact, time‐dependent analytical equations for spiral trajectories and matching gradient and density‐correction waveforms Open
Purpose To analytically define a spiral waveform and trajectory that match the constraints of gradient frequency, slew rate, and amplitude. Theory and Methods Piecewise analytical solutions for gradient waveforms under the desired constrai…
View article: High‐quality <scp>FLORET UTE</scp> imaging for clinical translation
High‐quality <span>FLORET UTE</span> imaging for clinical translation Open
Purpose To develop a robust 3D ultrashort‐TE (UTE) protocol that can reproducibly provide high‐quality images, assessed by the ability to yield clinically diagnostic images, and is suitable for clinical translation. Theory and Methods Buil…
View article: Simultaneous brain and neck time‐of‐flight MRA using spiral multiband with localized quadratic encoding
Simultaneous brain and neck time‐of‐flight MRA using spiral multiband with localized quadratic encoding Open
Purpose To develop a method that achieves simultaneous brain and neck time‐of‐flight (ToF) magnetic resonance angiography (MRA) within feasible scan timeframes. Methods Localized quadratic (LQ) encoding is efficient for both signal‐to‐nois…
View article: 4D lung MRI with high-isotropic-resolution using half-spoke (UTE) and full-spoke 3D radial acquisition and temporal compressed sensing reconstruction
4D lung MRI with high-isotropic-resolution using half-spoke (UTE) and full-spoke 3D radial acquisition and temporal compressed sensing reconstruction Open
Objective . To develop a respiratory motion-resolved four-dimensional (4D) magnetic resonance imaging (MRI) technique with high-isotropic-resolution (1.1 mm) using 3D radial sampling, camera-based respiratory motion sensing, and temporal c…
View article: Free‐breathing <scp>2D</scp> radial cine <scp>MRI</scp> with respiratory auto‐calibrated motion <scp>correction</scp> (<scp>RAMCO</scp>)
Free‐breathing <span>2D</span> radial cine <span>MRI</span> with respiratory auto‐calibrated motion <span>correction</span> (<span>RAMCO</span>) Open
Purpose To develop a free‐breathing (FB) 2D radial balanced steady‐state free precession cine cardiac MRI method with 100% respiratory gating efficiency using respiratory auto‐calibrated motion correction (RAMCO) based on a motion‐sensing …
View article: Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry
Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry Open
Computational fluid dynamics (CFD) simulations of respiratory airflow have the potential to change the clinical assessment of regional airway function in health and disease, in pulmonary medicine and otolaryngology. For example, in disease…
View article: Variable anisotropic FOV for 3D radial imaging with spiral phyllotaxis (VASP)
Variable anisotropic FOV for 3D radial imaging with spiral phyllotaxis (VASP) Open
Purpose To develop a new 3D radial trajectory based on the natural spiral phyllotaxis (SP), with variable anisotropic FOV. Theory & Methods A 3D radial trajectory based on the SP with favorable interleaving properties for cardiac imaging h…
View article: Cover Image, Volume 27, Issue 3
Cover Image, Volume 27, Issue 3 Open
Cover legend: This cover image, by Rachelle Crescenzi et al., is based on the Research Article Dissociable Longitudinal imaging reveals sub-hippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of…
View article: Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice
Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice Open
Tauopathies are neurodegenerative disorders characterized by abnormal intracellular aggregates of tau protein, and include Alzheimer's disease, corticobasal degeneration, frontotemporal dementia, and traumatic brain injury. Glutamate metab…
View article: Mapping the alterations in glutamate with Glu<scp>CEST MRI</scp> in a mouse model of dopamine deficiency
Mapping the alterations in glutamate with Glu<span>CEST MRI</span> in a mouse model of dopamine deficiency Open
Glutamate chemical exchange saturation transfer (Glu CEST ) MRI was used to measure metabolic changes in mice treated with 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine ( MPTP ) by mapping regional cerebral glutamate. The Glu CEST contrast …
View article: T1ρ Magnetic Resonance Imaging to Assess Cartilage Damage After Primary Shoulder Dislocation
T1ρ Magnetic Resonance Imaging to Assess Cartilage Damage After Primary Shoulder Dislocation Open
Background: Patients who suffer anterior shoulder dislocations are at higher risk of developing glenohumeral arthropathy, but little is known about the initial cartilage damage after a primary shoulder dislocation. T1ρ is a magnetic resona…
View article: High quality three‐dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla
High quality three‐dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla Open
Purpose To develop a new faster and higher quality three‐dimensional (3D) gagCEST MRI technique for reliable quantification of glycosaminoglycan (GAG) present in the human knee cartilages. Methods A new magnetization‐prepared 3D gradient e…