Gustavo Duarte Ferrari
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View article: Sex‐ and age‐specific respiratory alterations induced by prenatal exposure to the cannabinoid receptor agonist WIN 55,212‐2 in rats
Sex‐ and age‐specific respiratory alterations induced by prenatal exposure to the cannabinoid receptor agonist WIN 55,212‐2 in rats Open
Background and Purpose Cannabis legalization has risen in many countries, and its use during pregnancy has increased. The endocannabinoid system is present in the CNS at early stages of embryonic development, and regulates functional brain…
View article: IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exercise
IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exercise Open
Interleukin 6 (IL-6) acts as a pro and anti-inflammatory cytokine, has an intense correlation with exercise intensity, and activates various pathways such as autophagy and mitochondrial unfolded protein response. Also, IL-6 is interconnect…
View article: A multidisciplinary weight-loss program: the importance of psychological group therapy
A multidisciplinary weight-loss program: the importance of psychological group therapy Open
In addition to dietary factors and sedentary habits, there is a relationship between obesity and psychological variables, even without a clear distinction between cause, effect, and correlation. Despite this relationship, weight-loss progr…
View article: Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response
Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response Open
Oropouche virus (OROV) is an emerging arbovirus in South and Central Americas with high spreading potential. OROV infection has been associated with neurological complications and OROV genomic RNA has been detected in cerebrospinal fluid f…
View article: NOS3 Polymorphisms Can Influence the Effect of Multicomponent Training on Blood Pressure, Nitrite Concentration and Physical Fitness in Prehypertensive and Hypertensive Older Adult Women
NOS3 Polymorphisms Can Influence the Effect of Multicomponent Training on Blood Pressure, Nitrite Concentration and Physical Fitness in Prehypertensive and Hypertensive Older Adult Women Open
Associations of endothelial nitric oxide synthase (NOS3) polymorphisms with hypertension and response to exercise training in prehypertensive and hypertensive older adult women remain unclear. This study used a multicomponent program (vari…
View article: A freeze-and-thaw-induced fragment of the microtubule-associated protein tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity
A freeze-and-thaw-induced fragment of the microtubule-associated protein tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity Open
Tau is a microtubule-associated protein (MAP) responsible for controlling the stabilization of microtubules in neurons. Tau function is regulated by phosphorylation. However, in some neurological diseases Tau becomes aberrantly hyperphosph…
View article: Increased lipopolysaccharide‐induced hypothermia in neurogenic hypertension is caused by reduced hypothalamic PGE<sub>2</sub> production and increased heat loss
Increased lipopolysaccharide‐induced hypothermia in neurogenic hypertension is caused by reduced hypothalamic PGE<sub>2</sub> production and increased heat loss Open
Key points The mechanisms involved in hypothermia and fever during systemic inflammation (SI) remain largely unknown. Our data support the contention that brain‐mediated mechanisms are different in hypertension during SI. Considering that,…
View article: One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State
One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State Open
Evidence suggests that physical exercise has effects on neuronal plasticity as well as overall brain health. This effect has been linked to exercise capacity in modulating the antioxidant status, when the oxidative stress is usually linked…
View article: Moderate Exercise Modulates Tumor Metabolism of Triple-Negative Breast Cancer
Moderate Exercise Modulates Tumor Metabolism of Triple-Negative Breast Cancer Open
Triple-negative breast cancer (TNBC) stands out for its aggressiveness and accelerated rate of proliferation. Evidence shows that exercise may exert antitumorigenic effects, but the biochemical mechanisms underlying them remain unclear. Ou…
View article: Energy Metabolism and Redox State in Brains of Wistar Audiogenic Rats, a Genetic Model of Epilepsy
Energy Metabolism and Redox State in Brains of Wistar Audiogenic Rats, a Genetic Model of Epilepsy Open
The Wistar Audiogenic Rat (WAR) strain is a genetic model of epilepsy, specifically brainstem-dependent tonic-clonic seizures, triggered by acute auditory stimulation. Chronic audiogenic seizures (audiogenic kindling) mimic temporal lobe e…
View article: ASSOCIATION OF ACE AND ACTN3 GENETICS POLYMORPHISMS WITH FUNCTIONAL CAPACITY AND PREVALENCE OF FALLS AMONG WOMEN IN LATE ADULTHOOD AND EARLY OLD AGE
ASSOCIATION OF ACE AND ACTN3 GENETICS POLYMORPHISMS WITH FUNCTIONAL CAPACITY AND PREVALENCE OF FALLS AMONG WOMEN IN LATE ADULTHOOD AND EARLY OLD AGE Open
The objective of this study was to analyze the association of angiotensin-converting enzyme (ACE) I/D and alpha-actinin 3 (ACTN3) R/X genetics polymorphisms with functional capacity and fall prevalence in women in late adulthood and early …
View article: Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults
Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults Open
Obesity is a risk factor able to trigger several inflammatory alterations and the imbalance between pro- and anti-inflammatory cytokine productions. Physical exercise is an important strategy for reduction of inflammatory established proce…
View article: Associação de polimorfismos genéticos com capacidades físicas e composição corporal em idosas
Associação de polimorfismos genéticos com capacidades físicas e composição corporal em idosas Open
DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n1p11 The elderly population has grown substantially, and the decline in physical capacities and increase in the body fat percentage are important characteristics of aging. Genetic factors ma…