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View article: Correction: Kalisvaart et al. Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study. Cancers 2024, 16, 1954
Correction: Kalisvaart et al. Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study. Cancers 2024, 16, 1954 Open
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View article: Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties
Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties Open
View article: Biological Sample Collection to Advance Research and Treatment: A Fight Osteosarcoma Through European Research and Euro Ewing Consortium Statement
Biological Sample Collection to Advance Research and Treatment: A Fight Osteosarcoma Through European Research and Euro Ewing Consortium Statement Open
Osteosarcoma and Ewing sarcoma are bone tumors mostly diagnosed in children, adolescents, and young adults. Despite multimodal therapy, morbidity is high and survival rates remain low, especially in the metastatic disease setting. Trials i…
View article: Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study
Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study Open
Background: The decreased perfusion of osteosarcoma in dynamic contrast-enhanced (DCE) MRI, reflecting a good histological response to neoadjuvant chemotherapy, has been described. Purpose: In this study, we aim to explore the potential of…
View article: Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data
Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data Open
Extracellular vesicles (EVs) contain a plethora of biomolecules, including nucleic acids, with diverse diagnostic and therapeutic application potential. Although reverse transcription‐quantitative PCR (RT‐qPCR) is the most widely applied l…
View article: Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts
Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts Open
View article: Playing the infinite in sarcoma care and research
Playing the infinite in sarcoma care and research Open
View article: Evaluation of response to neoadjuvant chemotherapy in osteosarcoma using dynamic contrast-enhanced MRI: development and external validation of a model
Evaluation of response to neoadjuvant chemotherapy in osteosarcoma using dynamic contrast-enhanced MRI: development and external validation of a model Open
View article: Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts Open
Soft-tissue sarcomas (STS) are rare, heterogeneous cancers comprising 1% of adult and 15% of paediatric malignancies. Despite optimal treatment, 50%−80% of patients metastasize, even when they attain a status of minimal residual disease (M…
View article: 2022-RA-465-ESGO Pelvic exenteration with neurovascular and bony resections for gynaecological tumours: a systematic review
2022-RA-465-ESGO Pelvic exenteration with neurovascular and bony resections for gynaecological tumours: a systematic review Open
View article: Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?
Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up? Open
Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy…
View article: MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity
MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity Open
View article: Undifferentiated sarcoma of bone with a round to epithelioid cell phenotype harboring a novel <scp><i>EWSR1</i>‐<i>SSX2</i></scp> fusion identified by <scp>RNA</scp>‐based next‐generation sequencing
Undifferentiated sarcoma of bone with a round to epithelioid cell phenotype harboring a novel <span><i>EWSR1</i>‐<i>SSX2</i></span> fusion identified by <span>RNA</span>‐based next‐generation sequencing Open
Due to the increased application of RNA‐based next‐generation sequencing techniques on bone and soft tissue round cell sarcomas new fusions are frequently found, thereby expanding the molecular landscape of these tumors. In this report, we…
View article: Spindle cell/sclerosing rhabdomyosarcoma with a novel YAP1-MAML2 fusion in a 1-year-old: not all strongly TRK-expressing spindle cell sarcomas in infants are infantile fibrosarcomas!
Spindle cell/sclerosing rhabdomyosarcoma with a novel YAP1-MAML2 fusion in a 1-year-old: not all strongly TRK-expressing spindle cell sarcomas in infants are infantile fibrosarcomas! Open
View article: A challenging case of a poorly differentiated small cell variant of synovial sarcoma with unusual immunophenotype
A challenging case of a poorly differentiated small cell variant of synovial sarcoma with unusual immunophenotype Open
View article: Surgical Outcome and Oncological Survival of Osteofibrous Dysplasia-Like and Classic Adamantinomas
Surgical Outcome and Oncological Survival of Osteofibrous Dysplasia-Like and Classic Adamantinomas Open
Background: Osteofibrous dysplasia-like adamantinoma (OFD-AD) and classic adamantinoma (AD) are rare, neoplastic diseases with only limited data supporting current treatment protocols. We believe that our retrospective multicenter cohort s…
View article: Expandable distal femur megaprosthesis: A European Musculoskeletal Oncology Society study on 299 cases
Expandable distal femur megaprosthesis: A European Musculoskeletal Oncology Society study on 299 cases Open
Background and Objectives Expandable distal femur prostheses have become more popular over the last decades, but scientific data is limited. Methods A retrospective study was performed, including cases treated between 1986 and 2019 in 15 E…
View article: Enhancing rotational placement of reconstruction prostheses of the distal femur after sarcoma resection
Enhancing rotational placement of reconstruction prostheses of the distal femur after sarcoma resection Open
View article: NGS-analysis to the rescue: dual checkpoint inhibition in metastatic osteosarcoma – a case report and review of the literature
NGS-analysis to the rescue: dual checkpoint inhibition in metastatic osteosarcoma – a case report and review of the literature Open
Background: The prognosis and treatment of metastatic osteosarcoma have not changed in the last decades and the responses to chemotherapy in this setting are disappointing. In the past years, immunotherapy has found its place in the…
View article: Spindle cell haemangioma of the foot
Spindle cell haemangioma of the foot Open
View article: Aggressive Giant Cell tumour of the Metacarpal
Aggressive Giant Cell tumour of the Metacarpal Open
View article: Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection
Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection Open
Objective . In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was cre…