Hugo Celso Dutra de Souza
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View article: Gamma oryzanol modulates hepatic lipids expression and regulates integrated pathways in liver disease pathophysiology under a high sugar fat diet
Gamma oryzanol modulates hepatic lipids expression and regulates integrated pathways in liver disease pathophysiology under a high sugar fat diet Open
Diets high in simple carbohydrates and saturated fats increase the risk of liver diseases. Gamma oryzanol (ORY), a compound found in rice bran, shows promise in addressing metabolic liver diseases, though its impact on lipid pathways requi…
View article: Application of the WRF Model for Operational Wind Power Forecasting in Northeast Brazil
Application of the WRF Model for Operational Wind Power Forecasting in Northeast Brazil Open
Northeastern Brazil (NEB) has a high potential for wind energy generation, making it a strategic area for the development of this renewable source. However, the region’s complex wind regime, driven by interactions between large-scale atmos…
View article: Integrative cardiovascular study of adaptations induced by early ovariectomy in the hypertensive heart
Integrative cardiovascular study of adaptations induced by early ovariectomy in the hypertensive heart Open
This study reveals that early ovarian hormone deprivation worsens cardiac morphology and function in both normotensive and hypertensive rats. Using in vivo and ex vivo assessments, we found that the most pronounced effects of ovariectomy—n…
View article: Effect of inspiratory muscle training on respiratory muscle strength in patients undergoing high thoracic and abdominal surgery: An Integrative Review
Effect of inspiratory muscle training on respiratory muscle strength in patients undergoing high thoracic and abdominal surgery: An Integrative Review Open
Respiratory muscle training can mitigate respiratory muscle dysfunction resulting from thoracic and upper abdominal surgeries. This integrative review aimed to describe the effects of inspiratory muscle training (IMT) on respiratory muscle…
View article: Application of a good manufacturing practices checklist in food and nutrition units of a socio-educational foundation in the state of Pará, Brazil
Application of a good manufacturing practices checklist in food and nutrition units of a socio-educational foundation in the state of Pará, Brazil Open
The production and supply of meals must occur in an orderly and categorized manner, as quality in processing can negatively impact consumer health. In this context, evaluating good manufacturing and handling Practices through tools that ca…
View article: Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis
Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis Open
During the climacteric period, the decline in ovarian hormones leads to changes in the lipid profile. Physical exercise is the main non-pharmacological recommendation for controlling lipid levels. However, the effects on the lipid profile …
View article: Chronic acetylcholinesterase inhibition reduces the effects of physical training on ventricular contractility and coronary bed reactivity in hypertensive rats
Chronic acetylcholinesterase inhibition reduces the effects of physical training on ventricular contractility and coronary bed reactivity in hypertensive rats Open
Systemic arterial hypertension is accompanied by autonomic impairments that, if not contained, promotes cardiac functional and morphological damages. Pyridostigmine bromide (PYR) treatment results in positive effects on autonomic control a…
View article: Respiratory system impedance in different decubitus evaluated by impulse oscillometry in individuals with obesity
Respiratory system impedance in different decubitus evaluated by impulse oscillometry in individuals with obesity Open
Background and objective The body posture can influence gas exchange, respiratory mechanics, and mucociliary clearance and different positions can be used as a therapeutic strategy to improve in gas exchange and can also help physiotherapi…
View article: Physical Exercise Effects on Cardiovascular Autonomic Modulation in Postmenopausal Women—A Systematic Review and Meta-Analysis
Physical Exercise Effects on Cardiovascular Autonomic Modulation in Postmenopausal Women—A Systematic Review and Meta-Analysis Open
Background: The cardioprotective effect of physical exercise has been demonstrated in several studies. However, no systematic or updated analysis has described the effects of physical exercise on cardiovascular autonomic modulation in post…
View article: Human papillomavirus vaccination coverage in Brazilian North Region, 2013-2022
Human papillomavirus vaccination coverage in Brazilian North Region, 2013-2022 Open
Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fund…
View article: Combined effect of physical exercise and hormone replacement therapy on cardiovascular and metabolic health in postmenopausal women: A systematic review and meta-analysis
Combined effect of physical exercise and hormone replacement therapy on cardiovascular and metabolic health in postmenopausal women: A systematic review and meta-analysis Open
The cardioprotective effect of postmenopausal hormone replacement therapy (HRT) has been demonstrated in several studies. Similarly, physical exercise has yielded positive results. However, the effects of their combination remain inconclus…
View article: Impairment on Cardiovascular Autonomic Modulation in Women with Migraine
Impairment on Cardiovascular Autonomic Modulation in Women with Migraine Open
Autonomic dysfunction, such as reduced vagally mediated heart rate variability, has been suggested in headache patients but is still uncertain when considering primary headache disorders. This study aims to compare the heart rate and blood…
View article: Cardiovascular autonomic modulation differences between moderate-intensity continuous and high-intensity interval aerobic training in women with PCOS: A randomized trial
Cardiovascular autonomic modulation differences between moderate-intensity continuous and high-intensity interval aerobic training in women with PCOS: A randomized trial Open
Background Moderate-intensity continuous training (MICT) is strongly recommended for polycystic ovarian syndrome (PCOS) treatment. However, recent studies have suggested that high-intensity interval training (HIIT) would promote great bene…
View article: Integrative physiological study of adaptations induced by aerobic physical training in hypertensive hearts
Integrative physiological study of adaptations induced by aerobic physical training in hypertensive hearts Open
Aerobic physical training reduces arterial pressure in patients with hypertension owing to integrative systemic adaptations. One of the key factors is the decrease in cardiac sympathetic influence. Thus, we hypothesized that among other ca…
View article: Correlation among clinical, functional and morphological indexes of the respiratory system in non-cystic fibrosis bronchiectasis patients
Correlation among clinical, functional and morphological indexes of the respiratory system in non-cystic fibrosis bronchiectasis patients Open
Background Non-cystic fibrosis bronchiectasis (NCFB) is a heterogeneous disease, which assessment and severity can’t be defined by one particular instrument but using a multidimensional score. Thus, in additional to traditional methods, al…
View article: Increased airway resistance can be related to the decrease in the functional capacity in obese women
Increased airway resistance can be related to the decrease in the functional capacity in obese women Open
Background and objective Obesity can increase the airways resistance, mainly in the periphery, leading to dyspnea perception that can impair the functional capacity. This study aimed to analyze if airways resistance could be related to the…
View article: Handgrip strength is associated with risk of falls in physically active older women
Handgrip strength is associated with risk of falls in physically active older women Open
The authors of this study inquire about the association between handgrip strength (HGS) and the risk of falls in physically active older women. A cross-sectional study was conducted on 135 women between 50 and 90 years of age who were refe…
View article: Determining factors with regard to physical functional impairment in revascularized patients with acute coronary syndrome
Determining factors with regard to physical functional impairment in revascularized patients with acute coronary syndrome Open
Introduction: Functional physical capacity is indirectly associated with mortality, and may be compromised after a cardiovascular event, hence the importance of considering its prognostic factors during treatment in heart disease patients.…
View article: Effects of physical therapy with neuromuscular electrical stimulation in acute and late septic shock patients: A randomised crossover clinical trial
Effects of physical therapy with neuromuscular electrical stimulation in acute and late septic shock patients: A randomised crossover clinical trial Open
Background Patients with sepsis and immobility in the intensive care unit are associated with muscle weakness, and early mobilisation can counteract it. However, during septic shock, mobilisation is often delayed due to the severity of the…
View article: Examining Facilitators and Barriers to Cardiac Rehabilitation Adherence in a Low-Resource Setting in Latin America from Multiple Perspectives
Examining Facilitators and Barriers to Cardiac Rehabilitation Adherence in a Low-Resource Setting in Latin America from Multiple Perspectives Open
Cardiac rehabilitation (CR) is under-used, particularly in low-resource settings. There are few studies of barriers and facilitators to CR adherence in these settings, particularly considering multiple perspectives. In this multiple-method…
View article: Physical exercise is essential for cardiac autonomic regulation in hypertensive patients treated with losartan or enalapril
Physical exercise is essential for cardiac autonomic regulation in hypertensive patients treated with losartan or enalapril Open
Background Hypertension treatment with renin-angiotensin system inhibitors (RASi) presents contradictions in relation to the recovery of damage in cardiovascular autonomic control. Conversely, the association of RASi with aerobic physical …
View article: Role of aerobic physical training on cardiac autonomic and morphophysiological dysfunction in hypertensive rats subjected to ovarian hormone deprivation
Role of aerobic physical training on cardiac autonomic and morphophysiological dysfunction in hypertensive rats subjected to ovarian hormone deprivation Open
Here we investigated the effects of physical training on cardiovascular autonomic control and cardiac morphofunctional parameters in spontaneously hypertensive rats (SHRs) subjected to ovarian hormone deprivation. Forty-eight 10-week-old S…
View article: Effects of respiratory muscle training on parasympathetic activity in diabetes mellitus
Effects of respiratory muscle training on parasympathetic activity in diabetes mellitus Open
This study verified the effects of respiratory muscle training (RMT) on hemodynamics, heart rate (HR) variability, and muscle morphology in rats with streptozotocin-induced diabetes mellitus (DM). Thirty-six male Wistar rats were randomize…
View article: Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage
Aerobic physical training impact on adipokines in women with polycystic ovary syndrome – Effects of body fat percentage Open
The body fat potentiates metabolic impairments that may be harmful to women with PCOS. Aerobic training appears to promote an important beneficial effect on the metabolic regulation of adipokines, except TNF-α.
View article: Heart Rate Variability and Cardiovascular Fitness: What We Know so Far
Heart Rate Variability and Cardiovascular Fitness: What We Know so Far Open
Fluctuation analysis in intervals between heartbeats provides important indices related to autonomic modulation of heart rate variability (HRV). These indices are considered predictors of morbidity and mortality as they are frequently alte…
View article: Short-Term Aerobic Exercise Did Not Change Telomere Length While It Reduced Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study
Short-Term Aerobic Exercise Did Not Change Telomere Length While It Reduced Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study Open
Metabolic and hormonal outcomes of polycystic ovary syndrome (PCOS) have implications on telomere biology and physical activity may prevent telomere erosion. We sought to observe the effects of continuous (CAT) and intermittent (IAT) aerob…
View article: Short-term Aerobic Exercise did Not Change Telomere Length while it Reduces Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study.
Short-term Aerobic Exercise did Not Change Telomere Length while it Reduces Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study. Open
Background: Physical activity is an effective non-pharmacological treatment for polycystic ovary syndrome (PCOS) and the reproductive outcomes which may have implications on telomere biology. Objective: To observe the effects of continuous…
View article: Post-stenting chronic saphenous graft perforation: a seldom-reported condition
Post-stenting chronic saphenous graft perforation: a seldom-reported condition Open
A 69-year-old male with hypertension, dyslipidemia, and coronary artery disease (CAD) was admitted to the emergency room in December 2020 reporting chronic angina, with slight limitation to ordinary activities (Canadian Cardiovascular Soci…
View article: Effects of chronic cholinergic stimulation associated with aerobic physical training on cardiac morphofunctional and autonomic parameters in spontaneously hypertensive rats
Effects of chronic cholinergic stimulation associated with aerobic physical training on cardiac morphofunctional and autonomic parameters in spontaneously hypertensive rats Open
We investigated hemodynamic, cardiac morphofunctional, and cardiovascular autonomic adaptations in spontaneously hypertensive rats (SHRs) after aerobic physical training associated with chronic cholinergic stimulation. Fifty-four SHRs were…