Hiroshi Fukuda
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View article: Development of Tumor Microenvironment-Responsive Nanoparticles with Enhanced Tissue Penetration
Development of Tumor Microenvironment-Responsive Nanoparticles with Enhanced Tissue Penetration Open
Liposomes modified with slightly acidic pH-sensitive peptides (SAPSp-lipo) are effectively delivered to tumor tissues, followed by cellular uptake in the tumor microenvironment. Although SAPSp-lipo can penetrate tumor tissues via the inter…
View article: Lifestyle habits associated with elevated depressive symptoms among healthcare workers during the COVID-19 pandemic
Lifestyle habits associated with elevated depressive symptoms among healthcare workers during the COVID-19 pandemic Open
This study sought to explore the relationship between lifestyle changes among healthcare workers during the COVID-19 pandemic and positivity on the Center for Epidemiologic Studies-Depression Scale (CES-D). We also hypothesized that physic…
View article: Statistics of EUV exposed nanopatterns: Photons to molecular dissolutions
Statistics of EUV exposed nanopatterns: Photons to molecular dissolutions Open
For higher computing power of semiconductor integrated circuits, pattern feature sizes below 10 nm are anticipated by introducing extreme ultraviolet (EUV) lithography with high numerical aperture (NA) optics. However, performances of EUV …
View article: Effect and safety of pemafibrate for patients with type 2 diabetes mellitus and hypertriglyceridemia: a retrospective analysis of clinical data
Effect and safety of pemafibrate for patients with type 2 diabetes mellitus and hypertriglyceridemia: a retrospective analysis of clinical data Open
Not applicable.
View article: Efficacy of Oral Semaglutide after Switching from DPP-4 Inhibitors on Glucose Level and Body Weight Control in Japanese Type 2 Diabetes Patients with Obesity
Efficacy of Oral Semaglutide after Switching from DPP-4 Inhibitors on Glucose Level and Body Weight Control in Japanese Type 2 Diabetes Patients with Obesity Open
View article: SARS-CoV-2 seroprevalence among healthcare workers in a highly vaccinated Japanese medical center from 2020–2023
SARS-CoV-2 seroprevalence among healthcare workers in a highly vaccinated Japanese medical center from 2020–2023 Open
Infection-induced SARS-CoV-2 seroprevalence has been studied worldwide. At Juntendo University Hospital (JUH) in Tokyo, Japan, we have consistently conducted serological studies using the blood residue of healthcare workers (HCWs) at annua…
View article: Efficacy of oral semaglutide after switching from DPP-4 inhibitors in Japanese type 2 diabetes patients with obesity
Efficacy of oral semaglutide after switching from DPP-4 inhibitors in Japanese type 2 diabetes patients with obesity Open
Background Although these findings suggest that oral semaglutide may be a suitable treatment option for obese patients with type 2 diabetes mellitus inadequately responsive to dipeptidyl peptidase (DPP)-4 inhibitor–based therapy, evidence …
View article: Stochastic hotspots in extreme ultraviolet exposed nano-patterns as correlated molecular sub-cluster formation probabilities
Stochastic hotspots in extreme ultraviolet exposed nano-patterns as correlated molecular sub-cluster formation probabilities Open
Stochastic pattern anomalies limit the shrinking of the size of nano-patterns in extreme-ultraviolet lithography at around 10 nm due to the discrete/probabilistic nature of photon–electron-reaction systems. We express the patterns and thei…
View article: Association between serum uric acid levels and achievement of target blood pressure among Japanese community residents with hypertension
Association between serum uric acid levels and achievement of target blood pressure among Japanese community residents with hypertension Open
The authors examined the sex‐specific association between serum uric acid (SUA) levels and achievement of target blood pressure among Japanese patients with hypertension. This cross‐sectional study was conducted between January 2012 and De…
View article: Stochasticity in extreme-ultraviolet lithography predicted by principal component analysis of Monte Carlo simulated event distributions in resist films
Stochasticity in extreme-ultraviolet lithography predicted by principal component analysis of Monte Carlo simulated event distributions in resist films Open
Extremely low probability stochastic defects are becoming a major concern in extreme-ultraviolet (EUV) lithography due to the discrete/probabilistic nature of photons, photo- and secondary electrons, reactions, and (macro-) molecular disso…
View article: Localized and cascading secondary electron generation as causes of stochastic defects in extreme ultraviolet projection lithography (Erratum)
Localized and cascading secondary electron generation as causes of stochastic defects in extreme ultraviolet projection lithography (Erratum) Open
The Journal of Micro/Nanopatterning, Materials, and Metrology (JM3) publishes peer-reviewed papers on the core enabling technologies that address the patterning needs of the electronics industry.
View article: Cascade and cluster of correlated reactions as causes of stochastic defects in extreme ultraviolet lithography (Erratum)
Cascade and cluster of correlated reactions as causes of stochastic defects in extreme ultraviolet lithography (Erratum) Open
The Journal of Micro/Nanopatterning, Materials, and Metrology (JM3) publishes peer-reviewed papers on the core enabling technologies that address the patterning needs of the electronics industry.
View article: Heterogeneously integrated widely tunable laser using lattice filter and ring resonator on Si photonics platform
Heterogeneously integrated widely tunable laser using lattice filter and ring resonator on Si photonics platform Open
We fabricated a tunable laser consisting of a Si lattice filter, a Si ring resonator, and a III-V gain region. The lattice filter, a cascade of interferometers with the same delay length, has periodic transmission peaks with a wide free sp…
View article: Anomaly detection in random circuit patterns using autoencoder
Anomaly detection in random circuit patterns using autoencoder Open
Background: Systematic/stochastic pattern defects affect the production yield of integrated circuits (IC) containing trillions of 10-nm level features. Aim: We detect pattern anomalies/defects from images obtained from scanning electron mi…
View article: Response of Normal Tissues to Boron Neutron Capture Therapy (BNCT) with 10B-Borocaptate Sodium (BSH) and 10B-Paraboronophenylalanine (BPA)
Response of Normal Tissues to Boron Neutron Capture Therapy (BNCT) with 10B-Borocaptate Sodium (BSH) and 10B-Paraboronophenylalanine (BPA) Open
Boron neutron capture therapy (BNCT) is a cancer-selective radiotherapy that utilizes the cancer targeting 10B-compound. Cancer cells that take up the compound are substantially damaged by the high liner energy transfer (LET) particles emi…
View article: Efficacy and safety of semaglutide in glycemic control, body weight management, lipid profiles and other biomarkers among obese type 2 diabetes patients initiated or switched to semaglutide from other GLP-1 receptor agonists
Efficacy and safety of semaglutide in glycemic control, body weight management, lipid profiles and other biomarkers among obese type 2 diabetes patients initiated or switched to semaglutide from other GLP-1 receptor agonists Open
Purpose Evidence of the efficacy and safety of semaglutide among patients with type 2 diabetes who were initiated on or were switched to semaglutide from other GLP-1 RAs remains limited. The objective of this study was to investigate the s…
View article: Author Correction: SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo
Author Correction: SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo Open
View article: Efficacy and Safety of Semaglutide in Glycemic Control and Body Weight Management Among Obese Type 2 Diabetes Patients Initiated or Switched to Semaglutide From Other GLP-1 Receptor Agonists
Efficacy and Safety of Semaglutide in Glycemic Control and Body Weight Management Among Obese Type 2 Diabetes Patients Initiated or Switched to Semaglutide From Other GLP-1 Receptor Agonists Open
Background: Evidence of the efficacy and safety of semaglutide among patients with type 2 diabetes who were initiated on or were switched to semaglutide from other GLP-1 RAs remains limited. The objective of this study was to investigate t…
View article: An association between visceral or subcutaneous fat accumulation and diabetes mellitus among Japanese subjects
An association between visceral or subcutaneous fat accumulation and diabetes mellitus among Japanese subjects Open
View article: Association between Visceral or Subcutaneous Fat Accumulation and B-Type Natriuretic Peptide among Japanese Subjects: A Cross-Sectional Study
Association between Visceral or Subcutaneous Fat Accumulation and B-Type Natriuretic Peptide among Japanese Subjects: A Cross-Sectional Study Open
Background: Some previous studies have shown reduced levels of plasma B-type natriuretic peptide (BNP) in individuals with obesity. We aimed to estimate the relationship between BNP and abdominal fat distribution, adjusted for confounding …
View article: An association between subcutaneous fat mass accumulation and hypertension
An association between subcutaneous fat mass accumulation and hypertension Open
Evidence to assess relationships between subcutaneous fat area (SFA) and lifestyle‐related diseases, including hypertension, remains limited. The aim of this study was to investigate the relationship between SFA and hypertension. This stud…
View article: An association between visceral or subcutaneous fat accumulation and diabetes mellitus among Japanese subjects
An association between visceral or subcutaneous fat accumulation and diabetes mellitus among Japanese subjects Open
Background : The impact of subcutaneous fat accumulation remains controversial. This study assessed the association between visceral or subcutaneous fat area (VFA and SFA, respectively) and diabetes mellitus (DM) among Japanese subjects. M…
View article: An Association Between Visceral or Subcutaneous Fat Accumulation and Diabetes Mellitus Among Japanese Subjects
An Association Between Visceral or Subcutaneous Fat Accumulation and Diabetes Mellitus Among Japanese Subjects Open
Background : The impact of subcutaneous fat accumulation remains controversial. This study assessed the association between visceral or subcutaneous fat area (VFA and SFA, respectively) and diabetes mellitus (DM) among Japanese subjects. M…
View article: An impact of dietary intervention on blood pressures among diabetic and/or hypertensive patients with high cardiovascular disorders risk in northern Thailand by cluster randomized trial
An impact of dietary intervention on blood pressures among diabetic and/or hypertensive patients with high cardiovascular disorders risk in northern Thailand by cluster randomized trial Open
Background Global sodium intake remains above the recommended levels to control blood pressure (BP). We aimed to evaluate the efficacy of a dietary intervention on BP through salt reduction among community‐dwelling participants with high r…
View article: Serum zinc concentrations and characteristics of zinc deficiency/marginal deficiency among Japanese subjects
Serum zinc concentrations and characteristics of zinc deficiency/marginal deficiency among Japanese subjects Open
Background Studies that have examined serum zinc deficiency/marginal deficiency in developed countries, including Japan, are still limited. The aim of this study was to assess serum zinc concentrations and associated characteristics among …
View article: Cascade and cluster of correlated reactions as causes of stochastic defects in extreme ultraviolet lithography
Cascade and cluster of correlated reactions as causes of stochastic defects in extreme ultraviolet lithography Open
Background: Stochastic defects are becoming major concern in the future extreme ultraviolet (EUV) lithography as their probability Pd exponentially increases with decreasing feature size and is highly sensitive to variations in process/mas…
View article: Assessing lifestyle-related diseases with body and muscle mass using bioelectrical impedance analysis
Assessing lifestyle-related diseases with body and muscle mass using bioelectrical impedance analysis Open
View article: Cardiac Resynchronization Therapy for Improving Non-Uniform Thickening of Left Ventricular Wall: Assessment by Quantitative Gated Myocardial Perfusion SPECT
Cardiac Resynchronization Therapy for Improving Non-Uniform Thickening of Left Ventricular Wall: Assessment by Quantitative Gated Myocardial Perfusion SPECT Open
Cardiac resynchronization therapy (CRT) improves cardiac dyssynchrony in heart failure patients with a wide QRS electrocardiogram (ECG). Assessment of left ventricular (LV) dyssynchrony using echocardiography or other imaging modalities is…
View article: Membrane InGaAsP Mach-Zehnder modulator with SiN:D waveguides on Si platform
Membrane InGaAsP Mach-Zehnder modulator with SiN:D waveguides on Si platform Open
A high-efficiency InGaAsP Mach-Zehnder modulator is integrated with hydrogen-free deuterated silicon nitride (SiN:D) waveguide circuits on a Si substrate. A thin InP-based layer provides a high optical confinement factor of around 50% and …
View article: Estimating extremely low probability of stochastic defect in extreme ultraviolet lithography from critical dimension distribution measurement
Estimating extremely low probability of stochastic defect in extreme ultraviolet lithography from critical dimension distribution measurement Open
Projection lithography using extreme ultraviolet (EUV) light at 13.5-nm wavelength will be applied to the production of integrated circuits below 7-nm design rules. In pursuit of further miniaturization, however, stochastic pattern defect …