Explanipedia

Lung cancer screening in people who have never smoked: lessons from East Asia Open

H. Gilbert Welch, Wayne Gao, Fatima G. Wilder, So Yeon Kim, Gerard A. Silvestri · 2025

Wayne Gao and colleagues argue that high detection rates and high survival rates in never smokers are less likely to be evidence of screening benefit and more likely to be evidence of its harm—overdiagnosis

Operative Standards for Cancer Surgery: Will Synoptic Reporting Really Improve Cancer Outcomes? Open

Ton Wang, H. Gilbert Welch, Lesly A. Dossett · 2024

INTRODUCTION For most early-stage solid tumors, high-quality surgery represents the greatest potential for cure. While considerable attention has been given to the quality of diagnostic staging and adjuvant therapy, relatively little atten…

Deceptive measures of progress in the NHS long-term plan for cancer: case-based vs. population-based measures Open

Jason Oke, Sarah Jo Brown, Chris Senger, H. Gilbert Welch · 2023

The NHS Long Term Plan for cancer aims to increase early-stage diagnoses from 50% to 75% and to have 55,000 more people each year survive their cancer for at least 5 years following diagnosis. The targets measures are flawed and could be m…

Industry Payments Unrelated to Research Made to Physicians Across Medical Specialties Open

David Carr, H. Gilbert Welch · 2022

Clarification of Conflict of Interest Disclosures Open

Wayne Gao, Chi Pang Wen, H. Gilbert Welch · 2022

s Cancer Intervention and Surveillance Modeling Network model from the University of Michigan, for example, projects that the proportion of lung cancer deaths occurring in never smokers will rise from approximately 10% to more than 40% in …

Estimating Overdiagnosis of Melanoma Using Trends Among Black and White Patients in the US Open

Adewole S. Adamson, Elizabeth A. Suarez, H. Gilbert Welch · 2022

The discrepancies in incidence and mortality trends found in this cohort study suggest considerable overdiagnosis of melanoma occurring among White patients in the US.

Association of Computed Tomographic Screening Promotion With Lung Cancer Overdiagnosis Among Asian Women Open

Wayne Gao, Chi Pang Wen, Allison J. Wu, H. Gilbert Welch · 2022

This population-based ecological cohort study found that low-dose computed tomographic screening of mostly nonsmoking Asian women was associated with considerable lung cancer overdiagnosis. Five-year survival is biased by the increased LDC…

ASO Visual Abstract: Cancer in the Shadow of COVID: Early-Stage Breast and Prostate Cancer Patient Perspectives on Surgical Delays Due to COVID-19 Open

Claire Sokas, Masami Kelly, Christina Sheu, Julia Song, H. Gilbert Welch , et al. · 2021

Cancer in the Shadow of COVID: Early-Stage Breast and Prostate Cancer Patient Perspectives on Surgical Delays Due to COVID-19 Open

Claire Sokas, Masami Kelly, Christina Sheu, Julia Song, H. Gilbert Welch , et al. · 2021

Addressing overdiagnosis and overtreatment in cancer: a prescription for change Open

Laura J. Esserman, Ian M. Thompson, Brian Holden Reid, Peter S. Nelson, David F. Ransohoff , et al. · 2020

A vast range of disorders—from indolent to fast-growing lesions—are labelled as cancer. Therefore, we believe that several changes should be made to the approach to cancer screening and care, such as use of new terminology for indolent and…

The Effect of Treatment-Related Deaths and "Sticky" Diagnoses on Recorded Prostate Cancer Mortality Open

H. Gilbert Welch, Michael J. Barry, William C. Black, Xue Song, Elliott S. Fisher · 2020

Background: Although recorded cancer mortality should include both deaths from cancer and deaths from cancer treatment, there is evidence suggesting that the measure may be incomplete. To investigate the completeness of recorded prostate c…

Industry Payments to Physician Directors of National Cancer Institute–Designated Cancer Centers, 2015-2017 Open

David Carr, H. Gilbert Welch · 2019

This study examines industry payments made to physician directors of National Cancer Institute–designated cancer centers from 2015 through 2017.

Continuous Physiologic Monitoring: False Alarms and Overdiagnosis Open

Eric R. Coon, H. Gilbert Welch · 2018

Microscopic Screening of Reduction Mammoplasties Risks Overdiagnosis Open

Benjamin L. Mazer, H. Gilbert Welch · 2018

The study by Ambaye et al1 aptly demonstrates what many have known about cancer detection for decades: the more you look, the more you find. The authors' recommendation to extensively sample breast tissue obtained from older women undergoi…

The heterogeneity of cancer Open

H. Gilbert Welch · 2018

New diagnostic tests: more harm than good Open

Bjørn Hofmann, H. Gilbert Welch · 2017

Although new diagnostics may advance the time of diagnoses in selected patients, they will increase the frequency of false alarms, overdiagnosis, and overtreatment in others. Bjorn Hofmann and H. Gilbert Welch explain how to …

South Korea’s Thyroid-Cancer “Epidemic” — Turning the Tide Open

Hyeong Sik Ahn, H. Gilbert Welch · 2015

Since a physician coalition called attention to the extremely high incidence of diagnoses of thyroid cancer in South Korea and proposed that thyroid screening with ultrasonography be discouraged, there has been a marked decrease in the num…

Response to Strong Open

Wylie Burke, H. Gilbert Welch · 2015

H. Gilbert Welch YOU? Author Swipe