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View article: Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum
Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum Open
Background Mixed connective tissue disease (MCTD) has long been debated as an early nonspecific phase/symptom of differentiated connective tissue diseases (dCTD), similarly to interstitial pneumonia with autoimmune features (IPAF) and very…
View article: OP0288 PREGNANCY OUTCOMES IN AUTOINFLAMMATORY DISEASES: A PROSPECTIVE STUDY OF 117 CASES, INCLUDING 79 WITH FAMILIAL MEDITERRANEAN FEVER
OP0288 PREGNANCY OUTCOMES IN AUTOINFLAMMATORY DISEASES: A PROSPECTIVE STUDY OF 117 CASES, INCLUDING 79 WITH FAMILIAL MEDITERRANEAN FEVER Open
View article: Treatment of mixed connective tissue disease: A multicenter retrospective study
Treatment of mixed connective tissue disease: A multicenter retrospective study Open
View article: French protocol for the diagnosis and management of systemic lupus erythematosus
French protocol for the diagnosis and management of systemic lupus erythematosus Open
View article: Cyclophosphamide vs rituximab for eradicating inhibitors in acquired hemophilia A: A randomized trial in 108 patients
Cyclophosphamide vs rituximab for eradicating inhibitors in acquired hemophilia A: A randomized trial in 108 patients Open
View article: POS0166 OUTCOME OF PREGNANCY IN WOMEN WITH PRIMARY SJÖGREN’S SYNDROME COMPARED TO THE GENERAL POPULATION: THE FRENCH MULTICENTER PROSPECTIVE GR2 STUDY
POS0166 OUTCOME OF PREGNANCY IN WOMEN WITH PRIMARY SJÖGREN’S SYNDROME COMPARED TO THE GENERAL POPULATION: THE FRENCH MULTICENTER PROSPECTIVE GR2 STUDY Open
Background In the context of primary Sjögren's syndrome (pSS), only retrospective studies have investigated pregnancy outcomes with heterogeneous methods and contradictory results. An increased adverse pregnancy outcome (APO) frequency was…
View article: In-depth characterization of pulmonary arterial hypertension in mixed connective tissue disease: a French national multicentre study
In-depth characterization of pulmonary arterial hypertension in mixed connective tissue disease: a French national multicentre study Open
Objective Pulmonary arterial hypertension (PAH) is a leading cause of death in MCTD. We aimed to describe PAH in well-characterized MCTD patients. Methods MCTD patients enrolled in the French Pulmonary Hypertension Registry with a PAH diag…
View article: The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice
The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice Open
Neutralizing anti-factor VIII (FVIII) antibodies, known as FVIII inhibitors, represent a major drawback of replacement therapy in persons with congenital hemophilia A (PwHA), rendering further infusions of FVIII ineffective. FVIII inhibito…
View article: Cyclophosphamide vs Rituximab for Eradicating Inhibitors in Acquired Hemophilia A: A Randomized Trial in 108 Patients
Cyclophosphamide vs Rituximab for Eradicating Inhibitors in Acquired Hemophilia A: A Randomized Trial in 108 Patients Open
View article: Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients
Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients Open
Importance Catastrophic antiphospholipid syndrome (CAPS) is a severe, rare complication of antiphospholipid syndrome (APS), but cutaneous involvement has not yet been adequately described. Objective To describe cutaneous involvement during…
View article: Iloprost Duration for Digital Ulcers in Systemic Sclerosis: French Retrospective Study at Two Centers and Literature Review
Iloprost Duration for Digital Ulcers in Systemic Sclerosis: French Retrospective Study at Two Centers and Literature Review Open
Objective Ischemic digital ulcers (DUs) are frequent and severe complications of systemic sclerosis (SSc). Treatment options for SSc-related digital vasculopathy are based on aggressive vasodilation, with the objective to improve blood flo…
View article: The consequences of COVID-19 pandemic on patients with monoclonal gammopathy–associated systemic capillary leak syndrome (Clarkson disease)
The consequences of COVID-19 pandemic on patients with monoclonal gammopathy–associated systemic capillary leak syndrome (Clarkson disease) Open
View article: Hemorrhagic disseminated intravascular coagulation after 177Lu-Dotatate in metastatic midgut neuroendocrine tumor
Hemorrhagic disseminated intravascular coagulation after 177Lu-Dotatate in metastatic midgut neuroendocrine tumor Open
Rationale: Peptide receptor radionuclide therapy with 177 Lu-Dotatate represents a major breakthrough in the treatment of metastatic well differentiated neuroendocrine tumors. This treatment is generally well tolerated. Reported severe lon…
View article: Characterizing hospital pathways for the care of acquired hemophilia in France using comprehensive national health data
Characterizing hospital pathways for the care of acquired hemophilia in France using comprehensive national health data Open
View article: Hypercoagulability Evaluation in Antiphospholipid Syndrome without Anticoagulation Treatment with Thrombin Generation Assay: A Preliminary Study
Hypercoagulability Evaluation in Antiphospholipid Syndrome without Anticoagulation Treatment with Thrombin Generation Assay: A Preliminary Study Open
Antiphospholipid syndrome (APS) is associated with thrombotic events (tAPS) and/or obstetrical morbidity (oAPS), with persisting antiphospholipid antibodies (aPL). Despite an update of aPL in 2006, several patients had typical clinical eve…
View article: Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study
Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study Open
View article: Adaptation of recombinant activated factor VII in the treatment of acquired haemophilia A: Results from a prospective study (ACQUI-7) in France
Adaptation of recombinant activated factor VII in the treatment of acquired haemophilia A: Results from a prospective study (ACQUI-7) in France Open
Background: The efficacy and safety of recombinant activated factor VII (rFVIIa; NovoSeven®) in patients with acquired haemophilia A (AHA) are established; however, data on daily use in clinical practice for bleeding episodes are limited. …
View article: Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence
Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence Open
View article: Cardiac involvement in adult-onset Still's disease: Manifestations, treatments and outcomes in a retrospective study of 28 patients
Cardiac involvement in adult-onset Still's disease: Manifestations, treatments and outcomes in a retrospective study of 28 patients Open
View article: Vers le recours en première intention aux anticoagulants oraux directs dans le traitement de la maladie thromboembolique associée aux cancers
Vers le recours en première intention aux anticoagulants oraux directs dans le traitement de la maladie thromboembolique associée aux cancers Open
View article: Comparison of conventional immunosuppressive drugs versus anti-TNF-α agents in non-infectious non-anterior uveitis
Comparison of conventional immunosuppressive drugs versus anti-TNF-α agents in non-infectious non-anterior uveitis Open
DMARDs could still be used as first-line therapy for non-infectious non-anterior uveitis after corticosteroid therapy. However, anti-TNF-α agents could be proposed as an alternative in cases of severe inflammation or initial high level of …
View article: Risk factors for hydroxychloroquine retinopathy in systemic lupus erythematosus: a case–control study with hydroxychloroquine blood-level analysis
Risk factors for hydroxychloroquine retinopathy in systemic lupus erythematosus: a case–control study with hydroxychloroquine blood-level analysis Open
Objective HCQ is an essential medication in SLE, proven to lengthen survival and reduce flares. Its use, however, is limited by its rare but severe ophthalmological complications. Here, we aimed to analyse factors associated with HCQ retin…
View article: Artérite gigantocellulaire : apport de l’écho-doppler
Artérite gigantocellulaire : apport de l’écho-doppler Open
View article: Workload, well-being and career satisfaction among French internal medicine physicians and residents in 2018
Workload, well-being and career satisfaction among French internal medicine physicians and residents in 2018 Open
Objectives This work aimed to study the prevalence and risk factors associated with well-being and career satisfaction among French internal medicine physicians and residents. Methods A total of 1689 French internal medicine physicians or …
View article: Quelle place pour la recherche des anticorps antiphosphatidyléthanolamine dans la suspicion du syndrome des antiphospholipides séronégatif ?
Quelle place pour la recherche des anticorps antiphosphatidyléthanolamine dans la suspicion du syndrome des antiphospholipides séronégatif ? Open
View article: Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature
Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature Open
The association of granulomatosis with polyangiitis and pregnancy is rare and therapeutic options are limited by the risk of teratogenicity and fetotoxicity. There is a paucity of published literature to guide clinical decision-making in t…
View article: Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction
Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction Open
Antiphospholipid antibodies (aPL) promote endothelial dysfunction, inflammation and procoagulant state. We investigated the effect of hydroxychloroquine (HCQ) on prothrombotic state and endothelial function in mice and in human aortic endo…
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View article: Intravenous Immunoglobulins Improve Survival in Monoclonal Gammopathy-Associated Systemic Capillary-Leak Syndrome
Intravenous Immunoglobulins Improve Survival in Monoclonal Gammopathy-Associated Systemic Capillary-Leak Syndrome Open
View article: Lactose malabsorption in systemic sclerosis
Lactose malabsorption in systemic sclerosis Open
Summary Background There are no studies on systemic sclerosis ( SS c) assessing the relationship between food intake, especially lactose, and gastrointestinal dysfunction. Aim To determine the prevalence of lactose malabsorption, using lac…