Habibollah Mahmoodzadeh
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View article: Investigating Germ Cell Transition Genes in Breast Cancer: Exploring the Genesis of Cancer Testis-Associated Markers
Investigating Germ Cell Transition Genes in Breast Cancer: Exploring the Genesis of Cancer Testis-Associated Markers Open
Transition is an essential mechanism that drives the development of distinct cellular phenotypes and tumorigenesis. The expression of various types of testis cancer antigens (TCAs) in breast carcinomas suggests a potential transition to ma…
View article: “Colorectal Cancer Care Quality in a Developing Country: Insights from a Comparison of Teaching and Non-teaching Hospitals in Iran”
“Colorectal Cancer Care Quality in a Developing Country: Insights from a Comparison of Teaching and Non-teaching Hospitals in Iran” Open
Background Our study represents the first effort in the Eastern Mediterranean Region to identify disparities in the quality of colorectal cancer (CRC) care in Iran. Methods We established a collaborative registry program for non-metastatic…
View article: Identifying and Preserving Parathyroid Glands During Thyroid Surgery Using Indocyanine Green and a Review of the Literature
Identifying and Preserving Parathyroid Glands During Thyroid Surgery Using Indocyanine Green and a Review of the Literature Open
Background The research aims to investigate the potential use of near‐infrared fluorescence imaging with Indocyanine green (ICG) to detect the parathyroid glands (PGs) during surgery and to evaluate their blood supply. Additionally, a revi…
View article: Clinicopathological Factors Predisposing to No. 12a Lymph Node Metastasis in Gastric Cancer: A Prospective Cohort Analysis
Clinicopathological Factors Predisposing to No. 12a Lymph Node Metastasis in Gastric Cancer: A Prospective Cohort Analysis Open
Background The current standard surgical procedure for gastric cancer (GC) is gastrectomy and D2 lymphadenectomy, which includes harvesting No. 12a lymph node (LN) station. Aim The purpose of this study was to identify the clinicopathologi…
View article: Study of CDH1 germline mutation in hereditary diffuse gastric cancer and lobular breast cancer: a multicenter study in Iran
Study of CDH1 germline mutation in hereditary diffuse gastric cancer and lobular breast cancer: a multicenter study in Iran Open
Introduction: Mutations occurring in the CDH1 gene elevate the susceptibility to the development of hereditary diffuse gastric cancer (HDGC) as well as lobular breast cancer (LBC). LBCs with CDH1 germline mutations are classified as hered-…
View article: Electrochemotherapy for Recurrence and/or Metastatic Skin Cancers: A Prospective Case Series in Iran
Electrochemotherapy for Recurrence and/or Metastatic Skin Cancers: A Prospective Case Series in Iran Open
Purpose This study aimed to investigate the efficacy of electrochemotherapy on the three common types of skin cancer, including basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and melanoma. Methods 26 patients with sk…
View article: Probability of Tumor Lysis Syndrome in Electrochemotherapy of Large Solid Tumors: A Pilot Study
Probability of Tumor Lysis Syndrome in Electrochemotherapy of Large Solid Tumors: A Pilot Study Open
Background: Electrochemotherapy (ECT) has emerged as a promising targeted therapy to enhance drug delivery and minimize systemic side effects in cancer patients. However, concerns about tumor lysis syndrome (TLS) and other complications pe…
View article: Electrical Tumor Detection Probe Calibrated to Diagnose Gastrointestinal Cancer Mass in Real-Time
Electrical Tumor Detection Probe Calibrated to Diagnose Gastrointestinal Cancer Mass in Real-Time Open
Background: The primary objective of this research is to propose an intra-operative tumor detection probe calibrated on human models of gastrointestinal (G.I.) cancers, enabling real-time scanning of dissected masses. Methods: Electrical G…
View article: Is there any difference between <scp>Eastern</scp> and <scp>Western</scp> clinical practice guidelines in management of gastric cancer?
Is there any difference between <span>Eastern</span> and <span>Western</span> clinical practice guidelines in management of gastric cancer? Open
Background and Recent findings Gastric cancer (GC) has been known as one of the most common causes of cancer mortality both in Western and Eastern countries. However, there might be differences between how it is managed in different countr…
View article: Thoracic duct identification with indocyanine green fluorescence to prevent chyle leaks during minimally invasive esophagectomy
Thoracic duct identification with indocyanine green fluorescence to prevent chyle leaks during minimally invasive esophagectomy Open
Introduction Chylothorax (CT) is a rare yet serious complication after esophagectomy. Identification of the thoracic duct (TD) during esophagectomy is challenging due to its anatomical variation. Real‐time identification of TD may help to …
View article: Promotion of cardiac microtissue assembly within G-CSF-enriched collagen I-cardiogel hybrid hydrogel
Promotion of cardiac microtissue assembly within G-CSF-enriched collagen I-cardiogel hybrid hydrogel Open
Tissue engineering as an interdisciplinary field of biomedical sciences has raised many hopes in the treatment of cardiovascular diseases as well as development of in vitro three-dimensional (3D) cardiac models. This study aimed to enginee…
View article: Expression and Clinical Significance of IRE1-XBP1s, p62, and Caspase-3 in Colorectal Cancer Patients.
Expression and Clinical Significance of IRE1-XBP1s, p62, and Caspase-3 in Colorectal Cancer Patients. Open
Our findings indicated that XBP1s could be considered as a target for therapy in personalized medicine.
View article: The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer
The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer Open
Circular RNAs (circRNA) are known to function as competing endogenous RNA (ceRNA) in various cancers by regulating microRNAs (miRNA). However, in colorectal cancer (CRC), the precise pathological role of circ000240/miRNA/mRNA remains indet…
View article: Single-Cell Transcriptomics for Unlocking Personalized Cancer Immunotherapy: Toward Targeting the Origin of Tumor Development Immunogenicity
Single-Cell Transcriptomics for Unlocking Personalized Cancer Immunotherapy: Toward Targeting the Origin of Tumor Development Immunogenicity Open
Cancer immunotherapy is a promising approach for treating malignancies through the activation of anti-tumor immunity. However, the effectiveness and safety of immunotherapy can be limited by tumor complexity and heterogeneity, caused by th…
View article: Evaluation of miRNA-derived Extracellular Vesicles as Biomarkers in Ovarian Cancer Stem Cells
Evaluation of miRNA-derived Extracellular Vesicles as Biomarkers in Ovarian Cancer Stem Cells Open
Background and objectives: Ovarian cancer (OvCa) is the most deadly gynecological cancer.This study aimed to determine which genes and miRNAs play an important role in OvCa. Methods:We accessed the Gene Expression Omnibus database and down…
View article: Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions Open
Background: The surgery for a breast imaging-reporting and data system (BIRADS) IV lesions needs imaging or pathology supporting data. The roll of breast scintigraphy for this purpose is unclear. Materials and Methods: In a prospective des…
View article: The Expression Levels of Circulating miR-129 and miR-203a in Association with Breast Cancer and Related Metastasis
The Expression Levels of Circulating miR-129 and miR-203a in Association with Breast Cancer and Related Metastasis Open
Background: A significant part of deaths related to breast cancer is the result of invasion to other organs. It is essential to discover new non-invasive biomarkers to improve anticipation of recurrence risk in breast cancer patients. In t…
View article: Protocol for Dealing with Upper Gastrointestinal Cancers in the COVID-19 Outbreak in Cancer Institute of Tehran University of Medical Sciences
Protocol for Dealing with Upper Gastrointestinal Cancers in the COVID-19 Outbreak in Cancer Institute of Tehran University of Medical Sciences Open
Background: In March 2020, the World Health Organization (WHO) declared the novel COVID-19 infection a pandemic. Among high-risk patients infected by the virus, upper gastrointestinal cancer patients, similar to other immunosuppressed pati…
View article: MicroRNAs 7/17/155 As A Potential Breast Tumor Stemness miRNA Cluster: Detection of Breast Cancer Grade Specific miRNA-mRNA Interaction Network Inspiration from Mammary Gland Development
MicroRNAs 7/17/155 As A Potential Breast Tumor Stemness miRNA Cluster: Detection of Breast Cancer Grade Specific miRNA-mRNA Interaction Network Inspiration from Mammary Gland Development Open
Background The process of breast tumor dedifferentiation is complex and unclear. The mechanism represents the origin of the genesis and development of high-grade breast stem cells. It seems that microRNAs have crucial regulatory functions …
View article: A Panel of Circulating microRNAs as a Potential Biomarker for the Early Detection of Gastric Cancer
A Panel of Circulating microRNAs as a Potential Biomarker for the Early Detection of Gastric Cancer Open
Background: The high mortality rate of Gastric Cancer (GC) is a consequence of delayed diagnosis. The early diagnosis of GC could increase the five-year survival rate among patients. We aimed to find a panel of microRNAs (miRNA) for the de…
View article: Investigation of key signaling pathways and appropriate diagnostic biomarkers selection between non-invasive to invasive stages in pancreatic cancer: a computational observation
Investigation of key signaling pathways and appropriate diagnostic biomarkers selection between non-invasive to invasive stages in pancreatic cancer: a computational observation Open
Pancreatic cancer is the seventh most lethal cancer in the world. Despite its moderate prevalence, the 5-year survival rate of patients with pancreatic cancer is about 10%. Despite different therapeutic and diagnostic strategies for pancre…
View article: Transhiatal versus transthoracic esophagectomy for esophageal SCC: outcomes and complications
Transhiatal versus transthoracic esophagectomy for esophageal SCC: outcomes and complications Open
Background Transhiatal esophagectomy (THE) and transthoracic esophagectomy (TTE) are both accepted procedures for esophageal cancer but still the most effective surgical approach continues to be controversial. This study aimed to determine…
View article: A solitary precaval right renal artery: A case report
A solitary precaval right renal artery: A case report Open
Knowledge of aberrant renal vasculature is critical for preoperative planning of either open or minimally invasive renal surgery. A precaval right renal artery is a rare anatomical variant in which the artery passes anterior to the inferio…
View article: Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells
Stem Cell Therapy in Limb Ischemia: State-of-Art, Perspective, and Possible Impacts of Endometrial-Derived Stem Cells Open
As an evidence-based performance, the rising incidence of various ischemic disorders has been observed across many nations. As a result, there is a growing need for the development of more effective regenerative approaches that could serve…
View article: Protocol for dealing with Upper Gastrointestinal Cancers in the COVID-19 Outbreak in Cancer Surgery Centers
Protocol for dealing with Upper Gastrointestinal Cancers in the COVID-19 Outbreak in Cancer Surgery Centers Open
\nBackground:\n
\n\nIn March 2020, the World Health Organization declared the novel COVID-19 infection a pandemic. Among high-risk patients infected by the virus, upper gastrointestinal cancer patients similar to other immunosuppressed pat…
View article: Fever of unknown origin as the first presentation of candida vertebral osteomyelitis: A case report
Fever of unknown origin as the first presentation of candida vertebral osteomyelitis: A case report Open
Candida osteomyelitis is a rare disorder; however, its incidence has drastically risen especially during the last 3 decades. Diagnosis is usually delayed due to nonspecific symptoms. Thus, its management would not be performed at the prope…
View article: Evaluation of Sentinel Lymph Node Status and its Association with Clinicopathological Factors in Patients with Cutaneous Melanoma: A Retrospective Study
Evaluation of Sentinel Lymph Node Status and its Association with Clinicopathological Factors in Patients with Cutaneous Melanoma: A Retrospective Study Open
Background: Cutaneous Melanoma (CM) is cancer with rising prevalence worldwide. The most significant predictor of CM is regional lymph node metastasis. Sentinel Lymph Node (SLN) biopsy has been used to stage CM and to identify lymphatic me…