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View article: Limb biomechanics in combat sports: insights from wearable sensor technology
Limb biomechanics in combat sports: insights from wearable sensor technology Open
The application of wearable sensor technology in combat sports has created unprecedented opportunities for the objective, in-field analysis of limb biomechanics. This review synthesizes the current state of academic research on the use of …
View article: Global, regional, and national burden of Alzheimer’s disease and other dementias from 1990 to 2021: findings from the Global Burden of Disease Study 2021
Global, regional, and national burden of Alzheimer’s disease and other dementias from 1990 to 2021: findings from the Global Burden of Disease Study 2021 Open
Background As the global population continues to age, the growing number of elderly individuals has contributed to an increase in age-related conditions and illnesses, such as dementia, which places considerable financial and emotional pre…
View article: Oneta: Multi-Style Image Enhancement Using Eigentransformation Functions
Oneta: Multi-Style Image Enhancement Using Eigentransformation Functions Open
The first algorithm, called Oneta, for a novel task of multi-style image enhancement is proposed in this work. Oneta uses two point operators sequentially: intensity enhancement with a transformation function (TF) and color correction with…
View article: IUPHAR review: Microbiota-gut-brain axis and its role in neuropsychiatric disorders
IUPHAR review: Microbiota-gut-brain axis and its role in neuropsychiatric disorders Open
The human gut microbiome, composed of a vast array of microorganisms that have co-evolved with humans, is crucial for the development and function of brain systems. Research has consistently shown bidirectional communication between the gu…
View article: ANTIDEPRESSANT EFFECTS OF SILEXAN IN PATIENTS WITH PRIMARY ANXIETY SYNDROMES
ANTIDEPRESSANT EFFECTS OF SILEXAN IN PATIENTS WITH PRIMARY ANXIETY SYNDROMES Open
Background Anxiety and depressive diseases represent leading causes of burden worldwide with a globally increasing prevalence and suffering [1]. Although the heterogeneous clinical presentations do not always fully meet the criteria requir…
View article: Identification of the Highly Polymorphic Prion Protein Gene (PRNP) in Frogs (Rana dybowskii)
Identification of the Highly Polymorphic Prion Protein Gene (PRNP) in Frogs (Rana dybowskii) Open
Prion diseases are fatal neurodegenerative diseases that can be transmitted by infectious protein particles, PrPScs, encoded by the endogenous prion protein gene (PRNP). The origin of prion seeds is unclear, especially in non-human hosts, …
View article: The Real-world Effect of Long-acting Injectable Antipsychotics on Annual Medical Costs of Korean Schizophrenia Patients
The Real-world Effect of Long-acting Injectable Antipsychotics on Annual Medical Costs of Korean Schizophrenia Patients Open
Although the use of LAIs did not significantly lower the first-year medical costs of schizophrenia patients, they offer beneficial economic impacts over time by reducing hospitalization-associated costs. Future research should focus on lon…
View article: A Multi-Center, Open-Label, Single-Arm Study to Investigate the Early Effectiveness of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression Using a Mobile Self-Monitoring Application
A Multi-Center, Open-Label, Single-Arm Study to Investigate the Early Effectiveness of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression Using a Mobile Self-Monitoring Application Open
This study assesses the early effectiveness of esketamine nasal spray (ESK) in adults with treatment-resistant depression (TRD) 1 day after the first administration, as monitored through self-assessment via the mobile application, Esketami…
View article: Trends in Electroconvulsive Therapy Utilization in South Korea: Health Insurance Review Data From 2008 to 2018
Trends in Electroconvulsive Therapy Utilization in South Korea: Health Insurance Review Data From 2008 to 2018 Open
Objective The study aimed to analyze and clinically correlate 10-year trends in the demographic characteristics of patients receiving electroconvulsive therapy (ECT) to provide an overview of ECT utilization in South Korea.Methods Using he…
View article: The Risk of Dementia after Anesthesia Differs according to the Mode of Anesthesia and Individual Anesthetic Agent
The Risk of Dementia after Anesthesia Differs according to the Mode of Anesthesia and Individual Anesthetic Agent Open
: This study provides unique insights into the nuanced relationship between anesthesia, individual anesthetic agents, and the incidence of dementia. While confirming a general association between anesthesia exposure and dementia risk, this…
View article: Low Psychological Resilience Predict the Risk for Alcohol Use Disorder in General Population: National Mental Health Survey of Korea 2021
Low Psychological Resilience Predict the Risk for Alcohol Use Disorder in General Population: National Mental Health Survey of Korea 2021 Open
Diminished resilience is a prognostic indicator of increased likelihood of both lifetime and current alcoholism in the general population.
View article: Embitterment in Vietnam War Veterans Predicted by Symptoms of Posttraumatic Stress Disorder
Embitterment in Vietnam War Veterans Predicted by Symptoms of Posttraumatic Stress Disorder Open
Objective Research on the association between posttraumatic embitterment disorder (PTED) and other psychopathologies in veterans and adults aged ≥65 years is lacking. This study aimed to assess embitterment among elderly war veterans and i…
View article: The Potential Role of Aripiprazole Augmentation for Major Depressive Disorder with Anxious Distress in Naturalistic Treatment Setting
The Potential Role of Aripiprazole Augmentation for Major Depressive Disorder with Anxious Distress in Naturalistic Treatment Setting Open
: This study has shown additional benefit of ARPA treatment for MDDA patients in routine practice. However, adequately-powered and well-controlled studies are necessary for generalization of the present findings.
View article: Baseline symptom severity and efficacy of Silexan in patients with anxiety disorders: A symptom-based, patient-level analysis of randomized, placebo-controlled trials
Baseline symptom severity and efficacy of Silexan in patients with anxiety disorders: A symptom-based, patient-level analysis of randomized, placebo-controlled trials Open
The influence of baseline severity on the efficacy of Silexan, a proprietary essential oil from Lavandula angustifolia , in anxiety disorders has not been investigated in a pooled dataset. We report on an individual patient data analysis o…
View article: Circadian Rhythms and Depression in Adolescents: A Comparative Analysis of First Episode and Recurrent-Episode Groups
Circadian Rhythms and Depression in Adolescents: A Comparative Analysis of First Episode and Recurrent-Episode Groups Open
Circadian rhythm disruptions are a hallmark feature of mood disorders. Patients experiencing acute depressive episodes report noticeable changes in their sleep–wake cycles. This research explains the association between depression and vari…
View article: Circadian Rhythms and Depression in Adolescents: A Comparative Analysis of First Episode and Recurrent-Episode Groups
Circadian Rhythms and Depression in Adolescents: A Comparative Analysis of First Episode and Recurrent-Episode Groups Open
Circadian rhythm disruptions are a hallmark feature of mood disorders. Patients experiencing acute depressive episodes report noticeable changes in their sleep-wake cycles. This research explains the association between depression and vari…
View article: Exploring the Feasibility of Big Data Analytics in Disaster Psychiatry: Seoul Itaewon Tragedy’s Impact on Sentiment Distribution on Twitter (Preprint)
Exploring the Feasibility of Big Data Analytics in Disaster Psychiatry: Seoul Itaewon Tragedy’s Impact on Sentiment Distribution on Twitter (Preprint) Open
BACKGROUND Numerous studies have demonstrated the remarkable impact of disasters on mental health, with a substantial proportion of affected individuals developing psychiatric disorders. The timely identification of disaster-related menta…
View article: Development of a Korean Version of the Child Mania Rating Scale: Korean Validity and Reliability Study
Development of a Korean Version of the Child Mania Rating Scale: Korean Validity and Reliability Study Open
Objective Clinical rating scales are essential in psychiatry. The Young Mania Rating Scale is the gold standard for assessing mania. However, increased attention to pediatric bipolar disorder has led to the development of the Child Mania R…
View article: Effect of Frailty on Depression among Patients with Late-life Depression: A Test of Anger, Anxiety, and Resilience as Mediators
Effect of Frailty on Depression among Patients with Late-life Depression: A Test of Anger, Anxiety, and Resilience as Mediators Open
Given that anger, resilience, and anxiety influence the link between self-rated health and depression, interventions that lead to increased resilience and decreased anger and anxiety may be promising to reduce depressive symptoms in older …
View article: Additional Clinical Benefit of Agomelatine Treatment for Major Depressive Disorder in Naturalistic Treatment Setting
Additional Clinical Benefit of Agomelatine Treatment for Major Depressive Disorder in Naturalistic Treatment Setting Open
This study has shown additional benefit of AGO treatment as combination or switching agent for MDD patients without full remission in routine practice. However, adequately-powered and well-controlled studies are necessary for generalizatio…
View article: Antidepressant-induced mania in panic disorder: a single-case study of clinical and functional connectivity characteristics
Antidepressant-induced mania in panic disorder: a single-case study of clinical and functional connectivity characteristics Open
Background Mental health issues, including panic disorder (PD), are prevalent and often co-occur with anxiety and bipolar disorders. While panic disorder is characterized by unexpected panic attacks, and its treatment often involves antide…
View article: Cytokine Levels Reflect Tic Symptoms more Prominently During Mild Phases
Cytokine Levels Reflect Tic Symptoms more Prominently During Mild Phases Open
Various cytokines are involved in the neuroinflammatory circuitry of tic disorders. We aimed to identify the cytokines involved in the pathogenesis of tic disorders. We enrolled 44 patients with tic disorder and 38 healthy controls. Blood …
View article: Reliability and Validity of the Korean Version of the Brief Resilience Scale
Reliability and Validity of the Korean Version of the Brief Resilience Scale Open
: The Korean version of the Brief Resilience Scale is a valid and reliable instrument for evaluating resilience as the capacity to recover from adversity and endure obstacles or stress. This study also provides important evidence regarding…
View article: Associations between Pharmacological Treatment Patterns during the Initial Treatment Period and the Relapse or Recurrence of Anxiety Disorders: A Nationwide Retrospective Cohort Study
Associations between Pharmacological Treatment Patterns during the Initial Treatment Period and the Relapse or Recurrence of Anxiety Disorders: A Nationwide Retrospective Cohort Study Open
Although the importance of proper pharmacological treatment for preventing the relapse/recurrence of anxiety disorders is well known, a real-world data-based study has not been conducted. We aimed to investigate the effect of the initial p…
View article: Psychiatric manifestations of post-COVID-19 syndrome: the potential benefit of Silexan
Psychiatric manifestations of post-COVID-19 syndrome: the potential benefit of Silexan Open
Objective: Psychiatric symptoms are common and bothersome in individuals with post-COVID-19 syndrome. Because they are often mixed and subthreshold, established treatment regimens cannot be applied. There is an urgent need to identify ther…
View article: Impact of the Coronavirus Disease Pandemic on Mental Health Among School Students in Korea During the COVID-19 Pandemic
Impact of the Coronavirus Disease Pandemic on Mental Health Among School Students in Korea During the COVID-19 Pandemic Open
Prolonged COVID-19 might have had a significant impact on the mental health of adolescents who spent a lot of time at school. When comparing the years 2020 and 2021, middle and high school students were more affected by COVID-19 than eleme…