Aya Mousa
YOU?
Author Swipe
View article: Gestational weight gain and risk of adverse maternal and neonatal outcomes in observational data from 1.6 million women: systematic review and meta-analysis
Gestational weight gain and risk of adverse maternal and neonatal outcomes in observational data from 1.6 million women: systematic review and meta-analysis Open
Objective To synthesise evidence from contemporary populations (2009-24) across diverse world regions and income settings on associations between gestational weight gain (GWG) and broad clinical outcomes, to inform updated, globally releva…
View article: Diet and female fertility: a population-based study re-evaluating the need for prescriptive dietary patterns
Diet and female fertility: a population-based study re-evaluating the need for prescriptive dietary patterns Open
Introduction Diet may impact female fertility via inflammatory pathways, but the value of specific anti-inflammatory dietary indices compared with general healthy eating guidelines is unclear. We examined associations between different mea…
View article: Social Determinants of Smoking Among Young Adults in Jordanian Universities
Social Determinants of Smoking Among Young Adults in Jordanian Universities Open
The study demonstrates essential factors that contribute to smoking behaviors; one of them is friends who are smokers. Additionally, the lack of public health campaigns is a concern. Therefore, public health interventions targeting smoking…
View article: Trends in cardiometabolic conditions and pregnancy outcomes: a retrospective cohort study in South-Eastern Melbourne
Trends in cardiometabolic conditions and pregnancy outcomes: a retrospective cohort study in South-Eastern Melbourne Open
Objectives To examine trends in preconception and pregnancy cardiometabolic risk factors and conditions, pregnancy and birth complications, obstetric interventions, and the impact of COVID-19, and to forecast future disease burden. Design …
View article: Periodontitis and Metabolic Dysfunction-Associated Steatotic Liver Disease: emphasizing the clinical interplay between hepatologists and dentists
Periodontitis and Metabolic Dysfunction-Associated Steatotic Liver Disease: emphasizing the clinical interplay between hepatologists and dentists Open
This narrative review aims to elucidate the connection between periodontitis and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), which is currently the most prevalent liver disease. By raising awareness of this link, heal…
View article: Evaluation of machine learning and logistic regression-based gestational diabetes prognostic models
Evaluation of machine learning and logistic regression-based gestational diabetes prognostic models Open
Despite significant changes in the background characteristics of the population, we have demonstrated that all models remained robust, especially after recalibration. However, the performance of the original ML model decreased significantl…
View article: Metabolic associations of human placental lactogen in pregnancies at high metabolic risk: An observational cohort study
Metabolic associations of human placental lactogen in pregnancies at high metabolic risk: An observational cohort study Open
Introduction Human placental lactogen (hPL) is a placental hormone which, according to preclinical research, appears to have key metabolic roles in pregnancy. We aimed to examine pregnancy hPL levels in relation to maternal metabolic param…
View article: Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review
Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review Open
Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and…
View article: Metformin use in women with polycystic ovary syndrome ( <scp>PCOS</scp> ): Opportunities, benefits, and clinical challenges
Metformin use in women with polycystic ovary syndrome ( <span>PCOS</span> ): Opportunities, benefits, and clinical challenges Open
Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is charac…
View article: Long‐term effects of metformin on offspring health: A review of current evidence and future directions
Long‐term effects of metformin on offspring health: A review of current evidence and future directions Open
Metformin is widely prescribed for the management of type 2 diabetes mellitus, polycystic ovary syndrome, and gestational diabetes mellitus in pregnancy. Its use is driven by factors including oral administration, lower patient and health …
View article: Cost-Effectiveness of Interventions Related to the Treatment of Women With Polycystic Ovary Syndrome: A Scoping Review
Cost-Effectiveness of Interventions Related to the Treatment of Women With Polycystic Ovary Syndrome: A Scoping Review Open
The high proportion of fertility-related treatment studies reflects reproductive features often being the best-recognised feature of PCOS. However, limited evidence is available from LMICs. Further economic evidence is needed regarding PCO…
View article: Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial
Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial Open
Background: Trends in global ageing underscore the rising burden of age-related cognitive decline and concomitant cardiometabolic diseases, including type 2 diabetes mellitus (T2DM). Carnosine, a naturally occurring dipeptide with anti-inf…
View article: The effectiveness and safety of integrative medicine for chronic heart failure: An umbrella review
The effectiveness and safety of integrative medicine for chronic heart failure: An umbrella review Open
The evidence for most integrative medicine modalities for adjunctive management of HF remains limited. Well-designed and rigorous RCTs are needed, particularly with long-term follow up and evaluation of clinically meaningful outcomes.
View article: The Role of Nutrient Supplements in Female Infertility: An Umbrella Review and Hierarchical Evidence Synthesis
The Role of Nutrient Supplements in Female Infertility: An Umbrella Review and Hierarchical Evidence Synthesis Open
Background and Objectives: Nutrient supplements are commonly used to improve fertility outcomes by women with infertility trying to conceive spontaneously or utilising medically assisted reproduction (MAR). However, despite their widesprea…
View article: The Effect of Carnosine Supplementation on Musculoskeletal Health in Adults with Prediabetes and Type 2 Diabetes: A Secondary Analysis of a Randomized Controlled Trial
The Effect of Carnosine Supplementation on Musculoskeletal Health in Adults with Prediabetes and Type 2 Diabetes: A Secondary Analysis of a Randomized Controlled Trial Open
Background/Objectives: Type 2 diabetes (T2D) is associated with an increased risk of adverse musculoskeletal outcomes likely due to heightened chronic inflammation, oxidative stress, and advanced glycation end-products (AGE). Carnosine has…
View article: Exploring Causal Associations Between Serum Inflammatory Markers and Female Reproductive Disorders: A Mendelian Randomisation Study
Exploring Causal Associations Between Serum Inflammatory Markers and Female Reproductive Disorders: A Mendelian Randomisation Study Open
Although inflammation may disrupt immunoendocrine crosstalk essential for female reproductive function, causal links to disorders like polycystic ovary syndrome (PCOS) and endometriosis remain unestablished. This study aimed to utilise Men…
View article: Analyzing electronic medical records to extract prepregnancy morbidities and pregnancy complications: Toward a learning health system
Analyzing electronic medical records to extract prepregnancy morbidities and pregnancy complications: Toward a learning health system Open
Introduction Preexisting and pregnancy‐related medical conditions frequently co‐occur, leading to multimorbidity (≥2 morbidities) in pregnant women, and much of this information is in semi‐structured format in electronic medical records (E…
View article: International PCOS guideline clinical research priorities roadmap: a co-designed approach aligned with end-user priorities in a neglected women’s health condition
International PCOS guideline clinical research priorities roadmap: a co-designed approach aligned with end-user priorities in a neglected women’s health condition Open
The survey, International PCOS Guideline Network and 2018 and 2023 International PCOS Guidelines were funded by the Australian National Health and Medical Research Council (NHMRC) Centres of Research excellence in PCOS (APP1078444) and in …
View article: Carnosine Supplementation Has No Effect on Inflammatory Markers in Adults with Prediabetes and Type 2 Diabetes: A Randomised Controlled Trial
Carnosine Supplementation Has No Effect on Inflammatory Markers in Adults with Prediabetes and Type 2 Diabetes: A Randomised Controlled Trial Open
Background/Objectives: In vitro studies suggest that carnosine reduces inflammation by upregulating anti-inflammatory mediators and downregulating pro-inflammatory cytokines. However, human clinical trials examining the effects of carnosin…
View article: Blood-based inflammatory markers in female infertility: evidence from Mendelian randomization analysis
Blood-based inflammatory markers in female infertility: evidence from Mendelian randomization analysis Open
This is the first study to examine causal relationships between inflammation and female infertility using MR. Monocyte chemoattractant protein-1 and interleukin-8 are implicated in anovulatory infertility; however, only the relationship wi…
View article: Evidence-based guideline: premature ovarian insufficiency <sup>†</sup> <sup>‡</sup>
Evidence-based guideline: premature ovarian insufficiency <sup>†</sup> <sup>‡</sup> Open
The guideline provides healthcare professionals with clear advice on best practice in POI care, based on the best evidence currently available. In addition, a list of research recommendations is provided to guide further studies in POI.
View article: Prevalence and accurate diagnosis of polycystic ovary syndrome in adolescents across world regions: a systematic review and meta-analysis
Prevalence and accurate diagnosis of polycystic ovary syndrome in adolescents across world regions: a systematic review and meta-analysis Open
Objectives To examine the global prevalence of polycystic ovary syndrome (PCOS) among adolescents across world regions, comparing the 2003 Rotterdam consensus criteria with the current International Evidence-based PCOS Guideline criteria w…
View article: The Use of Multiple Medications During Pregnancy Among an Ethnically Diverse Population in South-Eastern Melbourne: A Retrospective Analysis to Explore Potential Risks and Complications
The Use of Multiple Medications During Pregnancy Among an Ethnically Diverse Population in South-Eastern Melbourne: A Retrospective Analysis to Explore Potential Risks and Complications Open
Medication use during pregnancy is prevalent, with many pregnant mothers taking multiple medications. Given the rising maternal age, body mass index, and morbidities in pregnancy, the use of medications during pregnancy is increasing. Such…
View article: Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines
Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines Open
BACKGROUND Biochemical hyperandrogenism is a hallmark and diagnostic feature of polycystic ovary syndrome (PCOS). However, the most accurate androgen measurement for assessing biochemical hyperandrogenism in PCOS diagnosis remains uncertai…
View article: Recommendations from the 2024 Australian evidence‐based guideline for unexplained infertility: <scp>ADAPTE</scp> process from the <scp>ESHRE</scp> evidence‐based guideline on unexplained infertility
Recommendations from the 2024 Australian evidence‐based guideline for unexplained infertility: <span>ADAPTE</span> process from the <span>ESHRE</span> evidence‐based guideline on unexplained infertility Open
Introduction The 2024 Australian evidence‐based guideline for unexplained infertility provides clinicians with evidence‐based recommendations for the optimal diagnostic workup for infertile couples to establish the diagnosis of unexplained…
View article: Summary of the 2023 international evidence‐based guideline for the assessment and management of polycystic ovary syndrome: an Australian perspective
Summary of the 2023 international evidence‐based guideline for the assessment and management of polycystic ovary syndrome: an Australian perspective Open
Introduction The Australian‐led 2023 International evidence‐based guideline for the assessment and management of polycystic ovary syndrome was based on best available evidence, clinical expertise and consumer preference. It followed best p…
View article: 2023 International Evidence‐Based Polycystic Ovary Syndrome Guideline Update: Insights From a Systematic Review and Meta‐Analysis on Elevated Clinical Cardiovascular Disease in Polycystic Ovary Syndrome
2023 International Evidence‐Based Polycystic Ovary Syndrome Guideline Update: Insights From a Systematic Review and Meta‐Analysis on Elevated Clinical Cardiovascular Disease in Polycystic Ovary Syndrome Open
Background Polycystic ovary syndrome (PCOS) is the most prevalent female endocrinopathy. Although increased cardiovascular risk factors are well established for the syndrome, PCOS remains overlooked within the realm of cardiology. We condu…