Bhavik Anil Patel
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View article: Investigating illicit dog health supplements using various analytical techniques
Investigating illicit dog health supplements using various analytical techniques Open
View article: Embodied carbon assessment of RCC residential buildings: Impact of varying seismic zones and floor area ratio in India
Embodied carbon assessment of RCC residential buildings: Impact of varying seismic zones and floor area ratio in India Open
India’s residential construction sector is a major emitter of greenhouse gases, with embodied carbon (EC) increasingly critical as operational emissions decline. This study quantifies EC in reinforced cement concrete (RCC) residential buil…
View article: A Comparative Study of Conductive 3D Printing Filaments for Electrochemical Sensing Applications Pretreated by Alumina Polishing, Electrochemical Activation, and Electrodeposition of Au Nanoparticles
A Comparative Study of Conductive 3D Printing Filaments for Electrochemical Sensing Applications Pretreated by Alumina Polishing, Electrochemical Activation, and Electrodeposition of Au Nanoparticles Open
3D-printed electrochemical devices have gained tremendous attention recently because they are highly customizable platforms for analysis and energy storage that can be produced using simple, inexpensive components in a wide variety of sett…
View article: Green 3D-printed electrochemical sensors: From construction to use
Green 3D-printed electrochemical sensors: From construction to use Open
The use of 3D printing for making electrochemical sensors has grown exponentially; however, most of these sensors are designed for single use. This contributes to significant plastic and chemical waste, which can be toxic and harmful to th…
View article: OS13.6.A A SINGLE-CELL AND SPATIAL ATLAS OF MENINGIOMA HETEROGENEITY ACROSS TUMOR CLASSES
OS13.6.A A SINGLE-CELL AND SPATIAL ATLAS OF MENINGIOMA HETEROGENEITY ACROSS TUMOR CLASSES Open
BACKGROUND Most meningiomas are benign, slow-growing tumors. However, CNS WHO grades 2 and 3 meningiomas display significantly higher aggressiveness and poorer prognosis. Recent investigations into the molecular biology of meningiomas have…
View article: PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites
PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites Open
PBK/TOPK is a mitotic kinase implicated in haematological and non-haematological cancers. Here we show that the key haemopoietic regulators Ikaros and Aiolos require PBK-mediated phosphorylation to dissociate from chromosomes in mitosis. E…
View article: Impurity Profiling of Some Anti - Cancer Drugs With Special Reference to Lazertinib
Impurity Profiling of Some Anti - Cancer Drugs With Special Reference to Lazertinib Open
A simple, specific, accurate and precise stability-indicating reversed-phase liquid chromatographic method had been developed and validated as per ICH guideline for Estimation of Lazertinib in its pharmaceutical dosage form (Tablet). Also,…
View article: Impurity Profiling Of Some Anti - Cancer Drugs With Special Reference To Repotrectinib
Impurity Profiling Of Some Anti - Cancer Drugs With Special Reference To Repotrectinib Open
A simple, specific, accurate and precise stability-indicating reversed-phase liquid chromatographic method had been developed and validated as per ICH guideline for Estimation of Repotrectinib in its pharmaceutical dosage form. Also, a for…
View article: Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis
Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis Open
In mammals, chromosome-wide regulatory mechanisms ensure a balance of X-linked gene dosage between males (XY) and females (XX). In female cells, expression of genes from one of the two X chromosomes is curtailed, with selective accumulatio…
View article: A comparative study of conductive 3D printing filaments for electrochemical sensing applications pretreated by alumina polishing, electrochemical activa-tion, and electrodeposition of Au nanoparticles
A comparative study of conductive 3D printing filaments for electrochemical sensing applications pretreated by alumina polishing, electrochemical activa-tion, and electrodeposition of Au nanoparticles Open
3D-printed electrochemical devices have gained tremendous attention recently because they are highly customizable platforms for analysis and energy storage that can be produced using simple, inexpensive components in a wide variety of sett…
View article: Detecting age-related changes in faecal vasoactive intestinal polypeptide using a 3D-printed electrochemical immunosensor
Detecting age-related changes in faecal vasoactive intestinal polypeptide using a 3D-printed electrochemical immunosensor Open
View article: Biomarkers of psychological stress are associated with increased susceptibility to the development of breast and prostate cancer in BRCA1/2 mutation carriers
Biomarkers of psychological stress are associated with increased susceptibility to the development of breast and prostate cancer in BRCA1/2 mutation carriers Open
View article: Exploring a new electrochemical treatment to significantly improve the electrochemical performance of 3D-printed polylactic acid/carbon fibre electrodes
Exploring a new electrochemical treatment to significantly improve the electrochemical performance of 3D-printed polylactic acid/carbon fibre electrodes Open
It is quite well-known that the differential pulse voltammetric technique (DPV) and a reversible redox probe of ruthenium hexamine (RuHex, [Ru(NH₃)₆]²⁺/3+) are commonly used in sensitively characterising the electrochemical performances of…
View article: 3D printed carbon and copper electrochemical sensors for the determination of reducing sugars to diagnose intestinal malabsorption
3D printed carbon and copper electrochemical sensors for the determination of reducing sugars to diagnose intestinal malabsorption Open
Malabsorption occurs when there is difficulty in digesting or absorbing key nutrients such as sugars from food. This often occurs in younger children or those with bowel disorders but is more prevalent in the elderly. Early diagnosis of su…
View article: Exploring a new electrochemical treatment to significantly improve the electrochemical performance of 3D-printed polylactic acid/carbon fibre electrodes
Exploring a new electrochemical treatment to significantly improve the electrochemical performance of 3D-printed polylactic acid/carbon fibre electrodes Open
It is quite well-known that the differential pulse voltammetric technique (DPV) and a reversible redox probe of ruthenium hexamine (RuHex, [Ru(NH₃)₆]²⁺/3+) are commonly used in sensitively characterising the electrochemical performances of…
View article: Deposition of gold nanoparticles is varied by different scales of various surface patterns on 3D printed electrodes
Deposition of gold nanoparticles is varied by different scales of various surface patterns on 3D printed electrodes Open
Fused Filament Fabrication (FFF) has provided the unique ability make electrochemical sensors with creative design. When commercial conductive filaments are 3D printed, the resultant electrodes often possess high contact resistance, and th…
View article: 3D printed electrode-microwell system: a novel electrochemical platform for miRNA detection
3D printed electrode-microwell system: a novel electrochemical platform for miRNA detection Open
3D printing has enabled the ability to make creative electrochemical well designs suitable for a wide field of electrochemical sensing. The demand for robust electrochemical systems is particularly high in diagnostics, where the rapid dete…
View article: Opportunistic Screening for Pancreatic Cancer using Computed Tomography Imaging and Radiology Reports.
Opportunistic Screening for Pancreatic Cancer using Computed Tomography Imaging and Radiology Reports. Open
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer, with most cases diagnosed at stage IV and a five-year overall survival rate below 5%. Early detection and prognosis modeling are crucial for improving patient outcomes …
View article: A comparative study of conductive 3D printing filaments for electrochemical sensing applications pretreated by alumina polishing, electrochemical activa-tion, and electrodeposition of Au nanoparticles
A comparative study of conductive 3D printing filaments for electrochemical sensing applications pretreated by alumina polishing, electrochemical activa-tion, and electrodeposition of Au nanoparticles Open
3D printed electrochemical devices have gained tremendous attention recently because they are highly customizable platforms for analysis and energy storage that can be produced using simple, inexpensive components in a wide variety of sett…
View article: Architectural design and dual nozzle 3D printing creates carbon thermoplastic multi-materials with enhanced conductivity
Architectural design and dual nozzle 3D printing creates carbon thermoplastic multi-materials with enhanced conductivity Open
View article: Monotherapy with tolterodine or mirabegron is insufficient for ameliorating cyclophosphamide-induced bladder overactivity in rats
Monotherapy with tolterodine or mirabegron is insufficient for ameliorating cyclophosphamide-induced bladder overactivity in rats Open
Monotherapy continues to be the most common pharmacological treatment option for patients with overactive bladder (OAB), despite evidence indicating that it may have inferior efficacy compared to combination therapy. This seems to be espec…
View article: Impurity Profiling of Some Anti-Cancer Drugs/Capivasertib
Impurity Profiling of Some Anti-Cancer Drugs/Capivasertib Open
A simple, specific, accurate and precise stability-indicating reversed-phase liquid chromatographic method had been developed and validated as per ICH guideline for Estimation of Capivasertib in its pharmaceutical dosage form. Also, a forc…
View article: Characterizing Behavioral Effects of Early-Life Stress in an Animal Model of Auditory Processing
Characterizing Behavioral Effects of Early-Life Stress in an Animal Model of Auditory Processing Open
Animal models provide significant insight into the development of typical and disordered sensory processing. Such models have been established to take advantage of physical and behavioral characteristics of specific species. For example, t…
View article: Two-phase Framework Clinical Question-Answering – Autocorrection for Guideline-concordance
Two-phase Framework Clinical Question-Answering – Autocorrection for Guideline-concordance Open
Use of large language models for generative tasks in critical domains like medicine is fraught with challenges like hallucination. In the domain of medicine, hallucination may take a unique shape where the LLM-generated language is not ina…
View article: A compliant mechanism actuated bistable hybrid mode triboelectric nanogenerator
A compliant mechanism actuated bistable hybrid mode triboelectric nanogenerator Open
Traditional contact-separation mode triboelectric nanogenerators (CS-TENGs) and lateral sliding mode TENGs exhibit distinct strengths and weaknesses in terms of their charge generation capability and durability. In this study, by leveragin…
View article: Decreases in mucosally‐evoked tachykinin signaling pathways can explain age‐related reductions in murine colonic motility patterns
Decreases in mucosally‐evoked tachykinin signaling pathways can explain age‐related reductions in murine colonic motility patterns Open
Background Increasing age increases the incidence of chronic constipation and fecal impaction. The contribution of the natural aging process to this phenotype is unclear. This study explored the effects of age on key motility patterns in t…
View article: Soft, Multifunctional MXene-Coated Fiber Microelectrodes for Biointerfacing
Soft, Multifunctional MXene-Coated Fiber Microelectrodes for Biointerfacing Open
Flexible fiber-based microelectrodes allow safe and chronic investigation and modulation of electrically active cells and tissues. Compared to planar electrodes, they enhance targeting precision while minimizing side effects from the devic…
View article: Subsets of Nanometer Vesicles in the Fly Release Differential Fractions of Vesicular Serotonin Content during Exocytosis
Subsets of Nanometer Vesicles in the Fly Release Differential Fractions of Vesicular Serotonin Content during Exocytosis Open
Serotonin, a monoamine neurotransmitter, is important in both the central nervous system (CNS) and the peripheral nervous system. Malfunction of serotonin signaling leads to various disorders. We studied serotonin signaling from serotonerg…
View article: Subsets of Nanometer Vesicles in the Fly Release Differential Fractions of Vesicular Serotonin Content during Exocytosis
Subsets of Nanometer Vesicles in the Fly Release Differential Fractions of Vesicular Serotonin Content during Exocytosis Open
Serotonin, a monoamine neurotransmitter, is important in both the central nervous system (CNS) and the peripheral nervous system. Malfunction of serotonin signaling leads to various disorders. We studied serotonin signaling from serotonerg…
View article: 3D-Printed Microelectrodes for Biological Measurement
3D-Printed Microelectrodes for Biological Measurement Open
Microelectrodes are useful electrochemical sensors that can provide spatial biological monitoring. Carbon fiber has been by far the most widely used microelectrode; however, a vast number of different materials and modification strategies …