H. Rogier van Doorn
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View article: Factors associated with positive blood cultures in children in nine African and Asian countries: the ACORN2 surveillance network
Factors associated with positive blood cultures in children in nine African and Asian countries: the ACORN2 surveillance network Open
Background Blood culture (BC) in children has relatively low diagnostic yield and high contamination rates, limiting cost-effectiveness. We aimed to determine readily available baseline characteristics to identify hospitalised children wit…
View article: The bacterial etiology and antimicrobial susceptibility of lower respiratory tract infections in Vietnam
The bacterial etiology and antimicrobial susceptibility of lower respiratory tract infections in Vietnam Open
View article: Context-specific impact of antimicrobial stewardship on antibiotic use and antibiotic resistance in hospitals in a lower-middle income country - results from an implementation study with a controlled interrupted time series design in Vietnam
Context-specific impact of antimicrobial stewardship on antibiotic use and antibiotic resistance in hospitals in a lower-middle income country - results from an implementation study with a controlled interrupted time series design in Vietnam Open
Introduction High-quality evidence regarding the impact of antimicrobial stewardship (AMS) is limited in Asia. In this study, we aimed to determine the effects of a pharmacist-led prospective audit with feedback intervention, as part of an…
View article: ĐẶC ĐIỂM CỦA NGƯỜI BỆNH VIÊM GAN VI RÚT C MẠN TÍNH TRƯỚC ĐIỀU TRỊ BẰNG PHÁC ĐỒ DAAS TẠI 02 BỆNH VIỆN BỆNH NHIỆT ĐỚI
ĐẶC ĐIỂM CỦA NGƯỜI BỆNH VIÊM GAN VI RÚT C MẠN TÍNH TRƯỚC ĐIỀU TRỊ BẰNG PHÁC ĐỒ DAAS TẠI 02 BỆNH VIỆN BỆNH NHIỆT ĐỚI Open
Mục tiêu: Mô tả đặc điểm cận lâm sàng và các đặc điểm nhân khẩu học của người bệnh viêm gan vi rút C mạn tính điều trị bằng thuốc kháng vi rút trực tiếp (DAAs) tại Bệnh viện Bệnh Nhiệt đới Trung ương (NHTD) và Bệnh viện Bệnh Nhiệt đới TP. …
View article: Treatment options to support the elimination of hepatitis C: an open-label, factorial, randomised controlled non-inferiority trial
Treatment options to support the elimination of hepatitis C: an open-label, factorial, randomised controlled non-inferiority trial Open
Wellcome Trust.
View article: Genomic characterization of blaOXA-48–carrying IncL plasmids in Enterobacterales in Vietnam
Genomic characterization of blaOXA-48–carrying IncL plasmids in Enterobacterales in Vietnam Open
Carbapenem-hydrolyzing β-lactamase (carbapenemase) genes have been disseminated among bacteria worldwide; however, only a few instances of bacterial isolates harboring the carbapenemase gene blaOXA-48have been reported in…
View article: Identifying context-specific determinants to inform improvement of antimicrobial stewardship implementation in healthcare facilities in Asia: results from a scoping review and web-based survey among local experts
Identifying context-specific determinants to inform improvement of antimicrobial stewardship implementation in healthcare facilities in Asia: results from a scoping review and web-based survey among local experts Open
International guidelines are available for the assessment and improvement of antimicrobial stewardship (AMS) programmes: an important strategy to address the escalating global antimicrobial resistance problem. However, existing AMS assessm…
View article: Đặc điểm kháng colistin của các chủng Klebsiella pneumoniae phân lập từ các hộ chăn nuôi khu vực Nam Định năm 2023
Đặc điểm kháng colistin của các chủng Klebsiella pneumoniae phân lập từ các hộ chăn nuôi khu vực Nam Định năm 2023 Open
Klebsiella pneumoniae là một trong các tác nhân hàng đầu gây nhiễm trùng cơ hội trên người, với khả năng đề kháng nhiều loại kháng sinh, được tìm thấy trong môi trường, hệ đường ruột của người, động vật. Gene đề kháng colistin mcr-1 và mcr…
View article: High Prevalence of Ceftriaxone-Resistant <i>Neisseria gonorrhoeae</i> in Hanoi, Vietnam, 2023–2024
High Prevalence of Ceftriaxone-Resistant <i>Neisseria gonorrhoeae</i> in Hanoi, Vietnam, 2023–2024 Open
Ceftriaxone resistance in Neisseria gonorrhoeae is an escalating global health concern, threatening the efficacy of empiric treatment. In the Asia-Pacific region, a rapid surge in ceftriaxone resistance has been observed, primarily associa…
View article: Review of the aetiologies of central nervous system infections in Vietnam
Review of the aetiologies of central nervous system infections in Vietnam Open
Central nervous system (CNS) infections are an important cause of morbidity and mortality in Vietnam, with many studies conducted to determine the aetiology. However, the cause remains unknown in a large proportion of cases. Although a sys…
View article: Klebsiella pneumoniae with capsule type K64 is overrepresented among invasive disease in Vietnam
Klebsiella pneumoniae with capsule type K64 is overrepresented among invasive disease in Vietnam Open
Introduction Recent reports indicate the emergence of community-acquired pneumonia associated with K64- Klebsiella pneumoniae (K. pneumoniae). Here, we identify the capsular types and sequence type of invasive and commensal K. pneumoniae i…
View article: Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium
Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium Open
The increasing threat from infection with drug-resistant pathogens is among the most serious public health challenges of our time. Formed by Wellcome in 2018, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium (SEDRI…
View article: Prevalence and determinants of nasal carriage of penicillin non-susceptible Streptococcus pneumoniae: a cross-sectional household survey in northern Vietnam
Prevalence and determinants of nasal carriage of penicillin non-susceptible Streptococcus pneumoniae: a cross-sectional household survey in northern Vietnam Open
View article: Prevalence and determinants of faecal carriage of carbapenem- and third-generation cephalosporin-resistant Enterobacterales: a cross-sectional household survey in northern Vietnam
Prevalence and determinants of faecal carriage of carbapenem- and third-generation cephalosporin-resistant Enterobacterales: a cross-sectional household survey in northern Vietnam Open
View article: Diagnostic Challenges and Gram-Negative Pathogen Dominance in Early- and Late-Onset Neonatal Sepsis in Manila, Philippines: A Prospective Observational Study
Diagnostic Challenges and Gram-Negative Pathogen Dominance in Early- and Late-Onset Neonatal Sepsis in Manila, Philippines: A Prospective Observational Study Open
View article: Context-Specific Impact Of Antimicrobial Stewardship On Antibiotic Use And Antibiotic Resistance In Hospitals In A Lower-Middle Income Country - Results From Implementation Study With A Controlled Interrupted Time Series Design In Vietnam
Context-Specific Impact Of Antimicrobial Stewardship On Antibiotic Use And Antibiotic Resistance In Hospitals In A Lower-Middle Income Country - Results From Implementation Study With A Controlled Interrupted Time Series Design In Vietnam Open
AIM: We aim to identify the impact of an antimicrobial stewardship (AMS) intervention, which includes pharmacist-led prospective audit with feedback, on hospital antibiotic use and resistance in two provincial-level general hospitals in Vi…
View article: Dilemmas of care: Healthcare seeking behaviours and antibiotic use among women in rural communities in Nam Dinh Province, Vietnam
Dilemmas of care: Healthcare seeking behaviours and antibiotic use among women in rural communities in Nam Dinh Province, Vietnam Open
Antimicrobial resistance is a silent pandemic to cause an estimated ten million deaths by 2050. Self-medication with antibiotics in low- and middle-income countries has been identified as a driver of antibiotic resistance. Interventions ta…
View article: C-reactive protein testing in primary care for acute respiratory infections: a cost-effective strategy to mitigate antimicrobial resistance across different income settings
C-reactive protein testing in primary care for acute respiratory infections: a cost-effective strategy to mitigate antimicrobial resistance across different income settings Open
Contains fulltext : 315004.pdf (Publisher’s version ) (Open Access)
View article: Hypothetical acceptability of minimally invasive tissue sampling and considerations for practice: A qualitative study in Vietnam
Hypothetical acceptability of minimally invasive tissue sampling and considerations for practice: A qualitative study in Vietnam Open
The exact aetiology of the cause of death (COD) remains unknown for a high proportion of deaths caused by infectious diseases. Complete diagnostic autopsy (CDA) is considered the gold standard to determine COD, but it is often not used in …
View article: Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in Laos
Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in Laos Open
Background Antimicrobial use in Laos is among the highest in Southeast Asia. The first Lao comprehensive antimicrobial prescribing guidelines have been available since 2021. This study explored the determinants of antibiotic prescribing de…
View article: Anti-SARS-CoV-2 antibody dynamics after primary vaccination with two-dose inactivated whole-virus vaccine, heterologous mRNA-1273 vaccine booster, and Omicron breakthrough infection in Indonesian health care workers
Anti-SARS-CoV-2 antibody dynamics after primary vaccination with two-dose inactivated whole-virus vaccine, heterologous mRNA-1273 vaccine booster, and Omicron breakthrough infection in Indonesian health care workers Open
Background Data on the dynamics and persistence of humoral immunity against SARS-CoV-2 after primary vaccination with two-dose inactivated vaccine (CoronaVac) are limited. This study evaluated the sequential effects of prior infection, het…
View article: OUCRU Outbreak Advisory Board in the COVID-19 Pandemic in Viet Nam
OUCRU Outbreak Advisory Board in the COVID-19 Pandemic in Viet Nam Open
Background Engagement between researchers and policy stakeholders plays a key role in facilitating collaboration and using research to inform health policies in Vietnam. As a leading health research institute in the region, the Oxford Univ…
View article: Understanding Acceptability and Willingness-to-pay for a C-reactive Protein Point-of-care Testing Service to Improve Antibiotic Dispensing for Respiratory Infections in Vietnamese Pharmacies: A Mixed-methods Study
Understanding Acceptability and Willingness-to-pay for a C-reactive Protein Point-of-care Testing Service to Improve Antibiotic Dispensing for Respiratory Infections in Vietnamese Pharmacies: A Mixed-methods Study Open
Background Pharmacies are popular first points of contact for mild infections in the community. Pharmacy services in many countries have expanded to include vaccines and point-of-care tests. In low- and middle-income countries such as Viet…
View article: Detection of co-infection and recombination cases with Omicron and local Delta variants of SARS-CoV-2 in Vietnam
Detection of co-infection and recombination cases with Omicron and local Delta variants of SARS-CoV-2 in Vietnam Open
View article: Molnupiravir or nirmatrelvir-ritonavir versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Molnupiravir or nirmatrelvir-ritonavir versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial Open
SUMMARY Background Molnupiravir and nirmatrelvir-ritonavir (Paxlovid) are oral antivirals that have been proposed as treatments for patients admitted to hospital with COVID-19. Methods In this randomised, controlled, open-label, adaptive p…
View article: Clinical presentation and treatment of 2 patients with infection caused by Chromobacterium violaceum in Vietnam
Clinical presentation and treatment of 2 patients with infection caused by Chromobacterium violaceum in Vietnam Open
View article: Antimicrobial resistance among common bacterial pathogens in Indonesia: a systematic review
Antimicrobial resistance among common bacterial pathogens in Indonesia: a systematic review Open
Wellcome Africa Asia Programme Vietnam.
View article: Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in the Laos
Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in the Laos Open
Background Antimicrobial use in the Laos is among the highest in the Southeast Asia region. The first Lao comprehensive antimicrobial prescribing guidelines have been available since 2021. This study explored the determinants of antibiotic…
View article: Antibiotic prescribing practices of medical doctors in a resource-limited setting and the influence of individual perceptions and stewardship support: a survey in three tertiary hospitals in Vietnam
Antibiotic prescribing practices of medical doctors in a resource-limited setting and the influence of individual perceptions and stewardship support: a survey in three tertiary hospitals in Vietnam Open
Objectives To understand antibiotic prescribing and influencing factors to inform antimicrobial stewardship (AMS) interventions to reduce unwanted consequences of antibiotic use in hospitals in Vietnam, a lower-middle-income country in Asi…
View article: Age-time-specific transmission of hand-foot-and-mouth disease enterovirus serotypes in Vietnam: A catalytic model with maternal immunity
Age-time-specific transmission of hand-foot-and-mouth disease enterovirus serotypes in Vietnam: A catalytic model with maternal immunity Open