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View article: One Step Closer to a Molecular Level Understanding of the Tear Film Lipid Layer by Surface X-ray Scattering
One Step Closer to a Molecular Level Understanding of the Tear Film Lipid Layer by Surface X-ray Scattering Open
The tear film lipid layer (TFLL) is the outermost layer of the tear film and forms a barrier between the eye and the environment. While the TFLL is important in maintaining ocular surface health, there remains a curtain of mystery surround…
View article: Decipher ‘Em All: A Profiling Study on the Effects of Acyl Groups in <i>O</i>-Acyl-ω-hydroxy Fatty Acids
Decipher ‘Em All: A Profiling Study on the Effects of Acyl Groups in <i>O</i>-Acyl-ω-hydroxy Fatty Acids Open
The O-acyl-ω-hydroxy fatty acids (OAHFAs) are an intriguing class of surface-active lipids which can be found in the human tear film lipid layer (TFLL). Recent studies have suggested that OAHFAs exist in the polar lipid layer and play a ce…
View article: Another Brick in the Wall of Tear Film Insights Added Through the Total Synthesis and Biophysical Profiling of <i>anteiso</i>-Branched Wax and Cholesteryl Esters
Another Brick in the Wall of Tear Film Insights Added Through the Total Synthesis and Biophysical Profiling of <i>anteiso</i>-Branched Wax and Cholesteryl Esters Open
The tear film lipid layer (TFLL) plays a vital part in maintenance of ocular health and represents a unique biological barrier comprising unusual and specialized lipid classes and species. The wax and cholesteryl esters (WEs and CEs) const…
View article: New Insights into the Molecular Structure of Tear Film Lipids Revealed by Surface X-ray Scattering
New Insights into the Molecular Structure of Tear Film Lipids Revealed by Surface X-ray Scattering Open
The tear film lipid layer (TFLL) is a unique biological membrane that serves a pivotal role in the maintenance of ocular surface health. Reaching an overarching understanding of the functional principle of the TFLL has been hampered by a l…