Hadi Javan
YOU?
Author Swipe
View article: Intravenous acellular human amniotic fluid prevents ischemic cardiac remodeling
Intravenous acellular human amniotic fluid prevents ischemic cardiac remodeling Open
Amniotic products are potent immunomodulators used clinically to repair tissue injury. This study sought to determine the impact of acellular human amniotic fluid (hAF) on cardiac remodeling. Amniotic fluid was obtained from volunteer dono…
View article: Cardiovascular Therapeutic Applications of the Human Amnion: Membrane, Cells, and Beyond
Cardiovascular Therapeutic Applications of the Human Amnion: Membrane, Cells, and Beyond Open
Background The therapeutic potential of the human amnion has been known since the early twentieth century. Subsequent study has revealed the further therapeutic potential of all elements of the amnion—membrane, cells, fluid—in the treatmen…
View article: Proteomic Characterization of Cardioprotective Human Acellular Amniotic Fluid
Proteomic Characterization of Cardioprotective Human Acellular Amniotic Fluid Open
Amniotic fluid-derived products are a promising resource for cell therapy and tissue engineering due to their anti-inflammatory, angiogenic, and antifibrotic properties. Human amniotic fluid (hAF) has been used in medical applications such…
View article: Circulating and Myocardial Cytokines Predict Cardiac Structural and Functional Improvement in Patients With Heart Failure Undergoing Mechanical Circulatory Support
Circulating and Myocardial Cytokines Predict Cardiac Structural and Functional Improvement in Patients With Heart Failure Undergoing Mechanical Circulatory Support Open
Background Recent prospective multicenter data from patients with advanced heart failure demonstrated that left ventricular assist device (LVAD) support combined with standard heart failure medications, induced significant cardiac structur…
View article: IKK-β inhibition prevents adaptive left ventricular hypertrophy
IKK-β inhibition prevents adaptive left ventricular hypertrophy Open
Most cardiovascular studies have implicated the central transcription factor nuclear factor kappa B (NF-κB) as contributing to the detrimental effects of cardiac injury. This ostensibly negative view of NF-κB competes with its important ro…
View article: Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading
Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading Open
Patients with heart failure (HF) and left ventricular assist devices (LVAD) have dysregulated thrombo-inflammatory responses, mediated in part by platelets. While studies of platelet activation have been undertaken in HF, changes in the pl…
View article: Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading
Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading Open
Patients with heart failure (HF) and left ventricular assist devices (LVAD) have dysregulated thrombo-inflammatory responses, mediated in part by platelets. While studies of platelet activation have been undertaken in HF, changes in the pl…