Hadis Jafarian
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View article: The prevalence of pediatric nosocomial fungal infections
The prevalence of pediatric nosocomial fungal infections Open
Background and Objectives: The aim of this study was to identify the incidence of nosocomial fungal infections in pediat- ric patients and evaluate the etiological agents, risk factors, and sites of infections. Materials and Methods: Clini…
View article: The frequency distribution of Aspergillus section Nigri from clinical and environmental samples in Iran
The frequency distribution of Aspergillus section Nigri from clinical and environmental samples in Iran Open
Background Aspergillus section Nigri is widely distributed in decaying plant materials in our environment. Although most of these species are known for food spoilage and some have industrial applications, some of these species, including A…
View article: Candida species in nephrology patients: biofilm formation, enzymatic activity, and genotyping
Candida species in nephrology patients: biofilm formation, enzymatic activity, and genotyping Open
Background Candiduria is a common form of candidiasis and can be asymptomatic in critically ill patients. Kidney illness patients may experience nosocomial infections, including candiduria. Detection of virulence factors in this species pl…
View article: A Perspective Study on Therapeutic Drug Monitoring of Voriconazole in Pediatric Patients with Hematologic Disorders
A Perspective Study on Therapeutic Drug Monitoring of Voriconazole in Pediatric Patients with Hematologic Disorders Open
Background: The incidence of invasive aspergillosis and the administration of voriconazole have risen among immunocompromised patients. Objectives: This study aimed to evaluate serum voriconazole concentration and its corresponding influen…
View article: Environmental surveillance of fungi and susceptibility to antifungal agents in tertiary care hospitals
Environmental surveillance of fungi and susceptibility to antifungal agents in tertiary care hospitals Open
This study aimed to evaluate the epidemiology of fungi in environment of tertiary care hospitals and their susceptibility patterns to seven antifungal agents for controlling and preventing fungal infections in patients. Environmental sampl…
View article: Comparison of in vitro activities of newer triazoles and classic antifungal agents against dermatophyte species isolated from Iranian University Hospitals: a multi-central study
Comparison of in vitro activities of newer triazoles and classic antifungal agents against dermatophyte species isolated from Iranian University Hospitals: a multi-central study Open
Background Dermatophytes have the ability to invade the keratin layer of humans and cause infections. The aims of this study were the accurate identification of dermatophytes by Polymerase Chain Reaction-Restriction Fragment Length Polymor…
View article: Epidemiology and Antifungal Susceptibility of<i>Candida</i>Species Isolated from 10 Tertiary Care Hospitals in Iran
Epidemiology and Antifungal Susceptibility of<i>Candida</i>Species Isolated from 10 Tertiary Care Hospitals in Iran Open
Candida species cause severe invasive infections of the heart, brain, eyes, bones, and other parts of the body. Knowledge of regional distributions of causative Candida agents and their antifungal susceptibility patterns can help to monito…
View article: Phenotype, genotype, and mating type determination in oral <i>Candida albicans</i> isolates from pediatric patients with neutropenia
Phenotype, genotype, and mating type determination in oral <i>Candida albicans</i> isolates from pediatric patients with neutropenia Open
Background The most frequent species of Candida to infect and colonize patients with neutropenia is still Candida albicans . This study aimed to provide detailed information on the phenotype, genotype, and mating type of oral C. albicans i…
View article: Significance of biomarkers in stewardship program in pediatric patients infected with Aspergillus species
Significance of biomarkers in stewardship program in pediatric patients infected with Aspergillus species Open
Background The potential use of biomarkers in the diagnosis of fungal infections is a challenge. The aim of this study was to evaluate the role of a biomarker-guided antifungal stewardship program for hospitalized pediatrics suffering from…
View article: Multicenter Study of Susceptibility of Aspergillus Species Isolated from Iranian University Hospitals to Seven Antifungal Agents
Multicenter Study of Susceptibility of Aspergillus Species Isolated from Iranian University Hospitals to Seven Antifungal Agents Open
Aspergillus species are the leading cause of invasive aspergillosis in immunocompromised hosts. The susceptibility of Aspergillus species to antifungal agents might be different.
View article: Antifungal activity of Taurolidine against Mucorales: an in-vitro study on clinical isolates
Antifungal activity of Taurolidine against Mucorales: an in-vitro study on clinical isolates Open
Background and Purpose: Taurolidine is active against a wide variety of microorganisms, including bacteria and fungi. Mucormycosis is one of the life-threatening opportunistic fungal infections, especially in immunocompromised patients. Cu…
View article: Evaluation of catalase activity of clinical and environmental isolates of Aspergillus species
Evaluation of catalase activity of clinical and environmental isolates of Aspergillus species Open
Background and Objectives: Catalases are a good scavenger of H2 O2 which degrades hydrogen peroxide into water and 2 2 oxygen. They are considered as a virulence factor that are present in both spores and hypha of fungi. There is limited d…
View article: Antifungal effect of sesame medicinal herb on Candida Species: original study and mini-review
Antifungal effect of sesame medicinal herb on Candida Species: original study and mini-review Open
The aim of this study was to evaluate the antifungal susceptibility patterns of three antifungals, methanolic extracts and N-hexane oil of sesame seeds on C. albicans and C. glabrata, isolated from oral cavity of liver transplant recipient…
View article: ABC typing and extracellular enzyme production of <i>Candida albicans</i> isolated from <i>Candida</i> vulvovaginitis
ABC typing and extracellular enzyme production of <i>Candida albicans</i> isolated from <i>Candida</i> vulvovaginitis Open
Background Candida albicans is the most common and virulent genus Candida . Detection of virulence factors in this species plays an important role in the better understanding of pathogenesis and antifungal treatment. Molecular typing inves…
View article: Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy
Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy Open
There is a worldwide concern regarding the antimicrobial resistance and the inappropriate use of antifungal agents, which had led to an ever-increasing antifungal resistance. This study aimed to identify the antifungal susceptibility of co…
View article: Genotyping, antifungal susceptibility, enzymatic activity, and phenotypic variation in <i>Candida albicans</i> from esophageal candidiasis
Genotyping, antifungal susceptibility, enzymatic activity, and phenotypic variation in <i>Candida albicans</i> from esophageal candidiasis Open
Background Esophageal candidiasis is the most frequent form of esophagitis. The pathogenicity of Candida spp. is related to a combination of microbial factors, hydrolytic enzyme secretion and phenotypic switching. This study was designed t…
View article: Molecular epidemiology of zygomycosis and their related factors in tertiary referral centers in southern Iran
Molecular epidemiology of zygomycosis and their related factors in tertiary referral centers in southern Iran Open
Introduction: For the best management of the zygomycosis in immunocompromised patients, the present study aims to detect and identify the etiologic agents by DNA sequencing method and their related factors in clinical samples of patients.
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View article: Development a hydrolysis probe-based quantitative PCR assay for the specific detection and quantification of Candida auris
Development a hydrolysis probe-based quantitative PCR assay for the specific detection and quantification of Candida auris Open
Background and Purpose: Candida auris is an emerging multidrug-resistant pathogen. The identification of this species with the conventional phenotypic or biochemical mycological methods may lead to misidentification. Molecular-based specie…
View article: Impact of antifungal stewardship interventions on the susceptibility of Candida species in pediatric patients with malignancy
Impact of antifungal stewardship interventions on the susceptibility of Candida species in pediatric patients with malignancy Open
Background There is a worldwide concern with respect to the antimicrobial resistance and the inappropriate use of antifungal agents, which had led to an ever-increasing antifungal resistance. This study aimed to identify the antifungal sus…
View article: Cerebral and pulmonary aspergillosis, treatment and diagnostic challenges of mixed breakthrough invasive fungal infections: case report study
Cerebral and pulmonary aspergillosis, treatment and diagnostic challenges of mixed breakthrough invasive fungal infections: case report study Open
Background Breakthrough invasive fungal infections (bIFIs) are an area of concern in the scarcity of new antifungals. The mixed form of bIFIs is a rare phenomenon but could be potentially a troublesome challenge when caused by azole-resist…
View article: Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016-2017) in Shiraz, Iran
Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016-2017) in Shiraz, Iran Open
Background: Surveillance of current changes in the epidemiology of Invasive Fungal Diseases (IFDs) as an important component of the antifungal stewardship programs (ASP), requires careful regular monitoring, especially in high-risk setting…
View article: Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016-2017) in Shiraz, Iran
Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016-2017) in Shiraz, Iran Open
Background: Surveillance of current changes in the epidemiology of Invasive Fungal Diseases (IFDs) as an important component of the antifungal stewardship programs (ASP), requires careful regular monitoring, especially in high-risk setting…
View article: Investigation of the Physical, Chemical Characteristics and Microbial Contamination of the Indoor Swimming Pools
Investigation of the Physical, Chemical Characteristics and Microbial Contamination of the Indoor Swimming Pools Open
In this study, some microorganisms were identified from the water pools. Effective management of swimming pools and proper control of the physical, chemical and microbiological property of water pools can produce the healthy recreational a…