Hummera Rafique
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View article: Recent Advancements and Perspectives of Low-Dimensional Halide Perovskites for Visual Perception and Optoelectronic Applications
Recent Advancements and Perspectives of Low-Dimensional Halide Perovskites for Visual Perception and Optoelectronic Applications Open
Low-dimensional (LD) halide perovskites have attracted considerable attention due to their distinctive structures and exceptional optoelectronic properties, including high absorption coefficients, extended charge carrier diffusion lengths,…
View article: Factors Affecting Return to Sports After Anterior Cruciate Ligament Reconstruction in Young Athletes at A Tertiary Care Hospital in Pakistan
Factors Affecting Return to Sports After Anterior Cruciate Ligament Reconstruction in Young Athletes at A Tertiary Care Hospital in Pakistan Open
Objective: To look for the factors associated with return to sports after anterior cruciate ligament reconstruction in young athletes at a tertiary care hospital in Pakistan. Study Design: Prospective longitudinal study. Place and Duration…
View article: Green synthesized cerium oxide nanorods using <i>Curcuma longa</i> extract for response surface methodology-based photocatalytic degradation application
Green synthesized cerium oxide nanorods using <i>Curcuma longa</i> extract for response surface methodology-based photocatalytic degradation application Open
In this study, green fabrication of cerium oxide (CeO 2 ) nanoparticles (CNRs) was achieved by utilizing Curcuma longa extract.
View article: INNOVATIVE UTILIZATION OF SOIL AMENDMENTS FOR IMPROVING RESISTANCE IN OKRA AGAINST MELOIDOGYNE INCOGNITA
INNOVATIVE UTILIZATION OF SOIL AMENDMENTS FOR IMPROVING RESISTANCE IN OKRA AGAINST MELOIDOGYNE INCOGNITA Open
Okra productivity is significantly hindered by various pests and pathogens, including bacteria, fungi, and nematodes, particularly Meloidogyne incognita, which poses a severe threat to plant growth and yield. This study aimed to evaluate t…
View article: Comparative Study of Post-Operative Functional Outcomes of Open Carpal tunnel Release vs. Arthroscopic Carpal tunnel Release
Comparative Study of Post-Operative Functional Outcomes of Open Carpal tunnel Release vs. Arthroscopic Carpal tunnel Release Open
Objective: This study aimed to compare treatment modalities OCTR and ACTR in treating carpel tunnel syndrome. This study assesses the important key indicators including symptom severity, functional status, pain intensity, time of recovery,…
View article: ASSESSMENT OF WHEAT GENOTYPES FOR THEIR LOW NITROGEN USE EFFICIENCY UNDER SEMI-ARID CONDITIONS OF PUNJAB, PAKISTAN
ASSESSMENT OF WHEAT GENOTYPES FOR THEIR LOW NITROGEN USE EFFICIENCY UNDER SEMI-ARID CONDITIONS OF PUNJAB, PAKISTAN Open
Nitrogen is one of the most important and critical macronutrients needed by plants for their optimal growth and development. The current experimental study was designed to examine the response of wheat variety Akbar-2019 under different ni…
View article: IMPACT OF VARIED AMOUNTS OF NITROGENOUS FERTILIZERS ON GRAIN YIELD AND RELATED AGRO-PHYSIOLOGICAL TRAITS IN SPRING WHEAT (TRITICUM AESTIVUM L.)
IMPACT OF VARIED AMOUNTS OF NITROGENOUS FERTILIZERS ON GRAIN YIELD AND RELATED AGRO-PHYSIOLOGICAL TRAITS IN SPRING WHEAT (TRITICUM AESTIVUM L.) Open
The application of nitrogen (N) is a critical factor influencing grain yield and agro-physiological traits in spring wheat (Triticum aestivum L.). This study aimed to evaluate the impact of varied nitrogen levels on grain yield and associa…
View article: An In‐Depth Review on Recent Progress in Synthetic Approaches and Biological Activities of Thiazol‐2( <i>3H</i> )‐Imine Derivatives
An In‐Depth Review on Recent Progress in Synthetic Approaches and Biological Activities of Thiazol‐2( <i>3H</i> )‐Imine Derivatives Open
This review presents the in‐dept analysis of the synthetic approaches towards thiazol‐2( 3H )‐imine and embarks at its various biological properties published during 2000 to 2023. The most important method of synthesis involves the reactio…
View article: Efficient removal of toxic azo dyes from contaminated water by adsorption on the GO surface
Efficient removal of toxic azo dyes from contaminated water by adsorption on the GO surface Open
The purpose of this study is to examine the possibility of GO to be used as an adsorbent for five novel potentially hazardous azo-dyes for their removal from aqueous solution. Adsorption characteristics of GO for azo-dyes removal were inve…
View article: Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives
Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives Open
The 1,3,4-oxadiazole derivatives Ox-6a-f have been synthesized by incorporating flurbiprofen moiety with the aim to explore the potential of target molecules to decrease the oxidative stress. The title compounds Ox-6a-f were prepared by si…
View article: Biodegradable Polymer Challenges
Biodegradable Polymer Challenges Open
After their intended use, the natural breakdown of synthetic polymeric materials into byproducts has always been regarded as a foremost challenge in recent years from the biodegradation perspective. The current chapter presents a comprehen…
View article: Investigation of multiferroic properties of dysprosium substituted bismuth ferrite (Bi1-xDyxFeO3) prepared by auto combustion technique
Investigation of multiferroic properties of dysprosium substituted bismuth ferrite (Bi1-xDyxFeO3) prepared by auto combustion technique Open
A simple and inexpensive auto combustion procedure was used to create the Bi1-xDyxFeO3 (x=0.0, 0.015, 0.03, 0.045, 0.060) multiferroics samples. In bismuth ferrite, the average crystallite size increased with growing Dy3+ concentration in …
View article: Synthesis, Carbonic Anhydrase II/IX/XII Inhibition, DFT, and Molecular Docking Studies of Hydrazide‐Sulfonamide Hybrids of 4‐Methylsalicyl‐ and Acyl‐Substituted Hydrazide
Synthesis, Carbonic Anhydrase II/IX/XII Inhibition, DFT, and Molecular Docking Studies of Hydrazide‐Sulfonamide Hybrids of 4‐Methylsalicyl‐ and Acyl‐Substituted Hydrazide Open
Carbonic anhydrases (CAs and EC 4.2.1.1) are the Zn 2+ containing enzymes which catalyze the reversible hydration of CO 2 to carbonate and proton. If they are not functioning properly, it would lead towards many diseases including tumor. S…
View article: Biodegradable Polymers Challenges
Biodegradable Polymers Challenges Open
After their intended use, the natural breakdown of synthetic polymeric materials into byproducts has always been regarded as a foremost challenge in recent years from the biodegradation perspective. The current chapter presents a comprehen…
View article: Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis
Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis Open
Tyrosinase and its related proteins are responsible for pigmentation disorders, and inhibiting tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can be effective inhibitors of tyrosinase activity, and…
View article: Methoxy-Substituted Tyramine Derivatives Synthesis, Computational Studies and Tyrosinase Inhibitory Kinetics
Methoxy-Substituted Tyramine Derivatives Synthesis, Computational Studies and Tyrosinase Inhibitory Kinetics Open
Targeting tyrosinase for melanogenesis disorders is an established strategy. Hydroxyl-substituted benzoic and cinnamic acid scaffolds were incorporated into new chemotypes that displayed in vitro inhibitory effects against mushroom and hum…
View article: CCDC 1988077: Experimental Crystal Structure Determination
CCDC 1988077: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1988078: Experimental Crystal Structure Determination
CCDC 1988078: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Sulfonamide‐Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics
Sulfonamide‐Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics Open
A series of sulfonamide‐bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N 2 H 4 to get aromatic sulfonyl hydrazid…
View article: Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo‐Substituted Mixed Ester/Amide‐Based Derivatives as Jack Bean Urease Inhibitors
Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo‐Substituted Mixed Ester/Amide‐Based Derivatives as Jack Bean Urease Inhibitors Open
A series of halo‐substituted mixed ester/amide‐based analogues 4a-l have been prepared as jack bean urease inhibitor, which showed good to excellent inhibition of enzyme activity. The role of halo‐substituted benzoyl moieties and alkyl sub…
View article: <p>Dexibuprofen amide derivatives as potential anticancer agents: synthesis, in silico docking, bioevaluation, and molecular dynamic simulation</p>
Dexibuprofen amide derivatives as potential anticancer agents: synthesis, in silico docking, bioevaluation, and molecular dynamic simulation Open
Based upon our wet lab and dry lab findings we propose that dexibuprofen analogue 4e may serve as a lead structure for the design of more potent anticancer drugs.
View article: Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives
Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives Open
The over expression of melanogenic enzymes like tyrosinase caused many hyperpigmentaion disorders. The present work describes the synthesis of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives 3a–e and 5a–e as antimelano…
View article: CCDC 1866050: Experimental Crystal Structure Determination
CCDC 1866050: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Electrochemical, spectroscopic and theoretical monitoring of anthracyclines’ interactions with DNA and ascorbic acid by adopting two routes: Cancer cell line studies
Electrochemical, spectroscopic and theoretical monitoring of anthracyclines’ interactions with DNA and ascorbic acid by adopting two routes: Cancer cell line studies Open
Pharmacodynamic interactions of three anthracycline antibiotics namely doxorubicin (DXH), epirubicin (EpiDXH) and daunorubicin (DNR) with DNA in the absence and presence of ascorbic acid (AA) as natural additive were monitored under physio…
View article: DENGUE FEVER
DENGUE FEVER Open
Background: Dengue fever (DF) is a mosquito-transmitted disease caused bythe dengue virus, an enveloped, single stranded RNA virus of flaviridae family. DF is widelydistributed in many countries of southeast and southern Asia, Central and …
View article: DENGUE FEVER
DENGUE FEVER Open
Background: Dengue fever (DF) is a mosquito-transmitted disease caused bythe dengue virus, an enveloped, single stranded RNA virus of flaviridae family. DF is widelydistributed in many countries of southeast and southern Asia, Central and …
View article: Antihyperlipidemic studies of newly synthesized phenolic derivatives: in silico and in vivo approaches
Antihyperlipidemic studies of newly synthesized phenolic derivatives: in silico and in vivo approaches Open
Based on our pharmacological evaluation, we may propose that compound 4a may act as a lead structure for the design and development of more potent antihyperlipidemic drugs.